Peter J Park
@peter_j_park
professor of biomedical informatics, bioinformatics/genomics with applications to cancer and neuroscience
Park Lab is hiring! After a pause during the pandemic, we are recruiting postdoctoral fellows, scientific programmers, software engineers, and data curators. Join us to do exciting science in a fun and collaborative environment in Boston! Please see compbio.hms.harvard.edu/position
Reminder: We're hiring! Join a team of faculty @harvardmed committed to developing AI systems that reduce rather than amplify healthcare disparities and augment rather than automate the essential human relationships in medicine. dbmi.hms.harvard.edu/careers/facult…
A Perspective piece on "The Somatic Mosaicism across Human Tissues Network", now published. Here is the description of the project from @TimCoorens
The cells in our bodies constantly acquire mutations. But what are the patterns of mutations across tissues? How do mutations in normal cells lead to disease? These and other questions we will tackle within the SMaHT Network, now described in @Nature nature.com/articles/s4158…
Happy to have been part of the 4D Nucleome program. So much data for understanding the 3D organization of the DNA in the nucleus--all freely available, on the portal that my lab has developed: data.4dnucleome.org
“Just the idea that 2-meter-long DNA can be wrapped up in a tiny cell is just mind-boggling” – Dr. Peter Park on how NIH-supported research led to key discoveries about DNA organization’s impact on health & disease. Watch the full video: youtu.be/2EQZg6Z-4S4
I am deeply saddened to hear of Atul's passing. I got to know him when he was finishing up his PhD in the HST program at MIT. What energy he had then, and how much he has accomplished at Stanford and then at UCSF!
Celebration of the life of Atul Butte. Join colleagues from three universities to celebrate him at 10 am PST on Saturday.
Thank you @CancerGrand for your support of the tissue specificity project over the last 5 years! It was a privilege to be collaborating with many wonderful colleagues on the question of tissue specificty of cancer driver mutations, as well summarized in this magazine.
The latest edition of our annual progress magazine Discover is now live! ⤵️ Read about: ➡️ key advances from our funded teams ➡️ the biggest themes in cancer research from early-onset cancers to AI and cancer as a systemic disease ➡️ our 7 new challenges features.cancerresearchuk.org/cancergrandcha…
To find a comprehensive set of somatic variants accurately, an individual-specific genome assembly is needed. Glad to be collaborating with @ChengChhy and @lh3lh3 for this new version of hifiasm; Flora Qu in the lab did extensive benchmarking.
New preprint on hifiasm (ONT)! We can now achieve near T2T human genome assembly using only ONT Simplex reads—in just half a day, with or without ultra-long sequencing. biorxiv.org/content/10.110…
Delighted to see my MIT graduate student Yifan @yifnzhao give a terrific thesis defense. She developed an algorithm for identifying CNVs in single cells (coming out in Nat Comm) and applied it to brain development (under review at Nat).
It takes a village: my advisor @peter_j_park, collaborators @ChrisAWalsh1, @_dianes_ & Mark Johnson, and DAC (@shaleklab & Po-Ru Loh). I'm beyond grateful for their incredible support.
Interactive circos plots now on cBioportal! Superb work from @dominikglodzik and @sehi_lyi.
Chromoscope now adds whole genome interpretation features to cBioportal! Interactively explore 2,583 cancer genomes from the PCAWG study, including structural variants with clinical relevance. Example genome analysis in the thread.
This Monday (10/28) at 5pm (Eastern Daylight Time): Info session about our bioinformatics/genomics PhD program! I will describe the basics and take your questions.
PhD in Biomedical Informatics applications accepted now through December 1. Join our virtual info sessions to learn more! - AI in Medicine (AIM) track 10/30 5pm ET harvard.zoom.us/webinar/regist… - Bioinformatics and Integrative Genomics (BIG) track 10/28 5pm ET harvard.zoom.us/meeting/regist…
How wonderful to see a South Korean win the big prize! I was incredibly lucky to have had some time to speak to her throughout the Ho-Am ceremony day in Seoul this past June - she was unassuming and pensive, and gave me some tips about the Korean language!
BREAKING NEWS The 2024 #NobelPrize in Literature is awarded to the South Korean author Han Kang “for her intense poetic prose that confronts historical traumas and exposes the fragility of human life.”
Had a wonderful time in Barcelona. It's been a privilege to be part of a Cancer Grand Challenge team for the last five years to think about the tissue specificity of cancer drivers!
We've been in Barcelona for @CancerGrand SPECIFICANCER'S final retreat. Led by @elledge_stephen (@BrighamWomens), funded by @CRUKresearch and @MarkFdn. They've uncovered key rules of cancer tissue specificity (why TSGs and Oncogenes cause cancer in some tissues but not in others)