Patrycja Kozik

Our work on perforin-2, a pore-forming protein expressed by #DendriticCells to deliver antigens into the cytosol during #CrossPresentation is now out in @ScienceMagazine science.org/doi/10.1126/sc…… Huge amount of work from Pablo, in collaboration with @laub_marco & @Pati_Krawczyk

#ScienceSaturday Dendritic cells (DCs) play a critical role in activating CD4 and CD8 positive T cells to mediate the immune response against cancers. ❓But which DCs are the most important in triggering cancer-specific T cells? ➡️ In a recent report published in…

Postdoc position in dendritic cell and cross-presentation biology - four days left to apply: mrc.tal.net/vx/mobile-0/ap… Join our team to work on these coolest cells ever! 🥰

Early-career researchers - One month left to apply for a funded place at our Immune Cell Interactions in Development, Homeostasis and Immunity Workshop, organised @BoussoLab, @griffiths_lab, @SarrisLab & Michael Sixt @ISTAustria biologists.com/workshops/febr… Deadline: 23 August

Thrilled to share our newest study in @ScienceMagazine. We created Boolean mice and CRISPR screened the heck outta ILC2s 🧵 1/ @MRC_LMB @wellcometrust @croucherFDN

Early-career researchers can now apply for a funded place at our Workshop "Immune Cell Interactions in Development, Homeostasis and Immunity" organised by @BoussoLab, @griffiths_lab, @SarrisLab & Michael Sixt @ISTAustria Find out more and apply at bit.ly/4dNRIW1

⏰ Closing date to apply for a postdoc position in our lab is on Apr 14th - Join us @MRC_LMB to work on the molecular mechanisms involved in antigen presentation in dendritic cells! mrc.tal.net/vx/mobile-0/ap… #PostdocJobs #AcademicTwitter

Izzy will move to the LMB for a postdoc with @patrycja_kozik . While we’re sad to see Izzy go, we’re also excited to see where her career takes her. 🧫🧬🥼🧪👩‍🔬

Delighted to share our latest work, out in @NatImmunol, tackling the seemingly inordinate complexity of #cDC2s. @ReiseSousaLab @TheCrick, we found that distinct ontogenetic lineages dictate cDC2 heterogeneity, rather than cell states imposed by the tissue microenvironment 🧵(1/x)

Many congratulations to @ekchilds_ who defended her PhD thesis today. Well done Dr. Childs! Thank you very much to @ActonLab and @patrycja_kozik for acting as examiners!

How can lysosomes, when ruptured, maintain stability allowing for repair? Glad to share @Nature nature.com/articles/s4158… the function of stress granules (SG) as molecular plugs that stabilise damaged membranes @TheCrick @maxgabgut #condensates #lysosomes #TB👇Thread

Elections time in Poland - fingers crossed 🤞 #wybory

Join us to work on dendritic cells, cross-presentation, and T cell priming @MRC_LMB - we have two postdoc positions available, deadline on Monday Sept 25th #CellBiology + #Immunology = 🥳 #PostdocJobs #AcademicTwitter

Perspective on a remarkable study by @patrycja_kozik exploring how Perforin-2 facilitates cell-associated Ag translocation from phagosome-to-cytosol in cDC1 cells. @RawatKSM Channeling antigens to CD8+ T cells | Science science.org/doi/10.1126/sc…

Perforin-2 is a pore-forming effector of endocytic escape in cross-presenting dendritic cells | Science science.org/doi/10.1126/sc…

Channeling antigens to CD8+ T cells | Science science.org/doi/10.1126/sc…