Victoria Aranda
@mvicaracal
Senior Editor, Clinical and Translational Medicine, @nature-all views my own
I'm happy to share that our article, published in @Nature (nature.com/articles/s4158…), highlighting the mutations occurring in our colon due to "L1 jumping genes". Genomic mosaicism by L1 jumping begins during early development and continues throughout an individual's lifetime!
Looking for something to read on the ✈️ home from #AACR23? Our April @NatureMedicine issue is now live! The cover by Niamh Mundy & @Marina_C_Spence highlights two of the #TRACERx #lungcancer studies. PLUS we have lots more #oncology #cancer research in this issue!
⚡️Our April issue is out!⚡️With two papers from the TRACERx #LungCancer study, clinical trials in #Diabetes and #ProstateCancer, studies on salt substitution for lowering #BloodPressure and on #AI for #BrainCancer diagnosis, news, opinions, and much more! nature.com/nm/volumes/29/…
I’m delighted that our paper on the Multicellularity Long Term Evolution Experiment (MuLTEE) has, at long last, been published. This paper establishes the foundations of what I’d like to work on for the rest of my career. 1/25 Free, full access link: rdcu.be/dbPA9
30. Nice summaries of today’s paper -> here from @NeehaZaidi nature.com/articles/d4158… -> here from @MSKCancerCenter mskcc.org/news/can-mrna-… And shareable link -> rdcu.be/dbPBq
Online at @nature: “Personalized RNA neoantigen vaccines stimulate T cells in pancreatic cancer” by @TheVinodLab nature.com/articles/s4158… #cancer #clinicaltrials
Excited to see several @NatureMedicine #neoadjuvant #immunotherapy trials in #melanoma highlighted in the ongoing #AACR23 clinical trials plenary session! Check out our new collection & call for papers in this research area with @Nature and @NatureComms: nature.com/collections/eb…
Amazing! Octopus and squid use cephalopod-specific chemotactile receptors (CRs). The octopus CRs are more recently evolved and expressed on its arms, which allows it to 'taste by touch' nature.com/articles/s4158…
Out in @Nature today, we describe a new method "PACER" to estimate clonal expansion rate and use it to identify that aberrant TCL1A activation as a cause of #CHIP expansion and potential therapeutic target @J__Stock @Jk_Gopakumar @jaiswalmdphd nature.com/articles/s4158…
So when does ecDNA arise, exactly? Our study on #ecDNA and the transformation of pre-cancerous Barrett’s esophagus into cancer is out today. This collaboration brought together @Team_eDyNAmiC, @RFitzgerald_lab and the @FredHutch Seattle Barrett’s Study.🧵 nature.com/articles/s4158…
Online at @nature: “Extrachromosomal DNA in the cancerous transformation of Barrett’s oesophagus” by @mischellab and colleagues #ecDNA #cancer nature.com/articles/s4158…