Martin-Villalba Lab
@molneurolab
Division of Molecular #Neurobiology @DKFZ German #CancerResearch Center. Tweets by lab members. Follow @amartinvill for tweets directly by Dr. Martin-Villalba
We're so excited to share our latest work “Identification of astrocyte-driven pseudolineages reveals clinical stratification and therapeutic targets in #Glioblastoma” spearheaded by @OghuzhanKaya on the wet & @LCForst on the dry lab as a preprint @Biorxiv biorxiv.org/content/10.110…
Faszinierende Studie! Wird hoffentlich neue Wege für die regenerative Medizin im ZNS ermöglichen
Forschende vom DKFZ & @UniHeidelberg haben gezeigt, dass Astrocyten, die im Gehirn Nervenzellen unterstützen, durch epigenetische Veränderungen zu Hirnstammzellen umprogrammiert werden. Diese Erkenntnis könnte für die regenerative Medizin genutzt werden. t1p.de/z3bvg
Check us out in the @KCStar! President and Chief Scientific Officer, @Planaria1, sat down with @katie_reports to discuss the exciting #regeneration #research happening at the Institute with #zebrafish, apple snails, #planarians & more! 🐌🧬 Read here: kansascity.com/news/local/art…
Nature research paper: DNA methylation controls stemness of astrocytes in health and ischaemia go.nature.com/4cO6j2d
🎉 Excited to share our latest study in @nature, showing that DNA🧬 #methylation is key to stemness in the adult #brain: nature.com/articles/s4158… A collaboration with @s_anders_m, driven by @LPMKremer and @SCerrizuela. #epigenetics #neuroscience #singlecell. Pre-print summary 🧵👇
We're excited to share our latest preprint where we use #singlecell #multiomics to show that stemness is encoded in the methylome of neural #stemcells (NSC) in the adult #brain 🐁🧠 #epigenetics #neuroscience #biorxiv_neursci 👉doi.org/10.1101/2022.0… 🧵1/9
An important finding that may lead to new ways of preserving brain health in the future "Astrocytes acquire stem cell function through changes in DNA methylation" nature.com/articles/s4158… @Nature @molneurolab @amartinvill and colleagues @justsaysinmice open-access
Scientists from DKFZ @molneurolab & @UniHeidelberg showed that epigenetic changes reprogram astrocytes into brain stem cells. This discovery shows that astrocytes could potentially be used in regenerative medicine to replace damaged nerve cells. @Nature ➡️ t1p.de/bctp1
And read the Research Briefing here: nature.com/articles/s4159…
.@LPMKremer, @molneurolab, @s_anders_m and colleagues introduce a data processing approach along with an easy-to-use software tool MethSCAn for scBS-seq data analysis. nature.com/articles/s4159…
I am excited to share my @TEDTalks at #TED2022 on how lab-grown neural cells and circuits can contribute to reverse engineering human brain development & uncover the biology of neuropsychiatric disorders ted.com/talks/sergiu_p… #assembloids #organoids #brain #Mentalhealth
Single nucleus RNA sequencing reveals glial cell type-specific responses to ischemic stroke biorxiv.org/content/10.110…
EMBO meeting on aging! Super exciting program: meetings.embo.org/event/24-aging And the meeting will take place in the gorgeous city of Nice, "baie des anges" (bay of angels) 🤩
Next on the #SRCKC23 stage is @amartinvill (@molneurolab) joined by graduate student @AlenaLaier from @DKFZ! #stemcells
Congratulations to @molneurolab on their latest @biorxivpreprint. Some great @ResolveBioSci #singlecell #spatialtranscriptomics data too...
We're so excited to share our latest work “Identification of astrocyte-driven pseudolineages reveals clinical stratification and therapeutic targets in #Glioblastoma” spearheaded by @OghuzhanKaya on the wet & @LCForst on the dry lab as a preprint @Biorxiv biorxiv.org/content/10.110…
I'm incredibly excited and proud to finally share the main results of my #PhD where together w/ @lcforst and @amartinvill we attempted to reveal organizational princples of #Glioblastoma through the lens of adult neural #StemCell biology @molneurolab @DKFZ #PrePrint #Tweetorial🧵
We're so excited to share our latest work “Identification of astrocyte-driven pseudolineages reveals clinical stratification and therapeutic targets in #Glioblastoma” spearheaded by @OghuzhanKaya on the wet & @LCForst on the dry lab as a preprint @Biorxiv biorxiv.org/content/10.110…