Maria Osmala
@mariaosmala
Bioinformatician and computational biologist
One step closer to unlocking the mystery of the genome:✅ Our researchers have uncovered more about the complex ‘language’ of the genome, providing interesting insights into gene regulation and human development 🧬 Read more here⬇️ bit.ly/3YqDzYK
Cracking the gene regulatory code! 🧬 DNA binding specificities for co-operative transcription factors and their analysis are now out. It was awesome to be a part of this work!
Nature research paper: DNA-guided transcription factor interactions extend human gene regulatory code go.nature.com/3Rahjyp
Exciting news from our latest collaboration between Prof. Jussi Taipale's Lab Group (taipalelabs.org) and Prof. Yimeng Yin's Lab: our comprehensive screen of 58,000+ transcription factor pairs is now published in @Nature: nature.com/articles/s4158… 1/10
Position in Taipale lab! 👩🔬👩💻🧬🧪🧫🔬academicpositions.co.uk/ad/wellcome-sa…
Teknologian kehittyminen avaa uusia näkökulmia tutkimukselle. Tuoreessa blogikirjoituksessa post-doc tutkija Siwei Zou Taipale-ryhmästä kertoo, kuinka edistykset kromatiinisekvensoinnissa mahdollistavat geenien säätelyn kattavamman tutkimisen.tumorgenetics.blog/2024/11/08/tra… @helsinkiuni
🧬 Prof. Jussi Taipale from @Cambridge_Uni dives into the advances in #genetranscription, driven by computational methods, and addresses the ethical challenges of sensitive health data in research. 🎥 Watch the interview from #ECCB2024 in Turku 👇 #Bioinformatics
#ECCB2024 continues with the keynote talk ”Towards predicting gene expression from sequence” by Prof. Jussi Taipale @Cambridge_Uni.
Oriented nucleosome binding by the pioneer factor ELF2 biorxiv.org/cgi/content/sh… #biorxiv_biochem
In our latest blog post, Petros Papadopoulos (Taipale Lab) stresses the importance of social interactions in the life and success of a scientist. tumorgenetics.blog/2024/02/29/the…
New blog out: "What Can The Genomes of 240 Placental Mammal Species Tell Us About Gene Regulation in Cancer?" by @mariaosmala in the Taipale Lab tumorgenetics.blog/2023/08/15/pla…
#ismbeccb2023 in Lyon is bigger than ever! Looking forward to talks and posters in @ISCB_RegSys COSI starting today. I present a poster (B-337) about computational analysis of transcription factor motifs produced in #JussiTaipale Lab. @HelsinkiUniMed @CoEinTG


📚Currently in the middle of our exciting #Tutorial session!💻 We're diving deep into the world of containerization and learning how to build containers. 🐳 It's fantastic to see so many enthusiastic participants joining us! 🌟 #Containerization #LearningTogether #ISMBECCB2023
Great meeting and fruitful discussions with @CoEinTG partners and the scientific advisory board at Majvik! Also researchers from the @CancerRegFi presented their studies.
@CoEinTG Fascinating updates and important discussions at the SAB (Scientific Advisory Board) meeting of the Centre of Excellence in Tumor Genetics today. Tomorrow we will continue with workshops to discuss further and deepen our collaborations. #cancerresearch
1/3 Excited to share our novel #CRISPR method out in @NatureBiotech! Thanks to #JussiTaipale, Otto, @Sahu_B, Teemu for help and contributions and @HelsinkiUniMed @SuomenAkatemia @CoEinTG @Syopasaatio @SigridJuselius #JAES @The_MRC @CR_UK for support! nature.com/articles/s4158…
ChromDMM: A Dirichlet-Multinomial Mixture Model For Clustering Heterogeneous Epigenetic Data academic.oup.com/bioinformatics…
ChromDMM: A Dirichlet-Multinomial Mixture Model For Clustering Heterogeneous Epigenetic Data biorxiv.org/cgi/content/sh… #bioRxiv
My 10 min of fame this morning on Finnish TV: on AI, research funding and something even on AI basic research: areena.yle.fi/1-50908758 . #ylenaamu #TuringAIFellows @OfficialUoM @FCAI_fi @AaltoUniversity
An updated model on transcriptional regulatory elements and a review of recent insights into the determinants of enhancer and promoter activities. Joint work with @albin_san nature.com/articles/s4157… (corrected link)
Enhancer prediction in the human genome by probabilistic modeling of the chromatin feature patterns biorxiv.org/cgi/content/sh… #biorxiv_bioinfo