Jun Wu Lab
@leo_jwu
Stem Cells, Embryo Models, and Interspecies Chimeras. Weird is the new normal!
Thank you Yuta for inviting and hosting me! It was a fun visit and I had the chance to meet several pioneers of developmental and stem cell biology! Truly inspired!
Dr. Jun Wu from University of Texas Southwestern Medical Center visited IRCMS and gave us a lecture for 124th IRCMS Seminar, with about 45 participants exchanging ideas and opinions. ✨🧬
Have you ever wondered how your back formed? The human embryo makes a neural tube (future spinal cord) and somites (trunk muscle/bone) from ~d20. They’re formed at the same time and place, so we used human Trunk-like Structures (hTLS) to investigate their ‘co-development’… (1/7)
Ridding cells of mitochondria sheds light on their function: Newsroom - UT Southwestern, Dallas, Texas utsouthwestern.edu/newsroom/artic… Thank you @UTSWScience for highlighting our study!
Now online! Unraveling mitochondrial influence on mammalian pluripotency via enforced mitophagy dlvr.it/TLH6Gr
Excited to share our new study in Cell—congrats to Daniel, co-authors, and our collaborators in the @PeterLyLab What began as pure curiosity led to a tool for modulating mitochondrial abundance in vitro and in vivo. A new direction for the Wu lab begins! cell.com/cell/fulltext/…
Stem cell-based models of early human development Read this Development at a Glance Article by Lizhong Liu @LLizhong and Jun Wu @leo_jwu: journals.biologists.com/dev/article/15…
Stem cell-based models of early human development journals.biologists.com/dev/article-ab…
Pluripotent cell states and fates in human embryo models pubmed.ncbi.nlm.nih.gov/40171916/ Thanks to Berna and Patrick for a great effort
Step inside a day in the life of @TheDouglasLab, as he studies the long-term effects of brain injuries. Explore his lab and see how scientists like him are driving progress - just in time for the @UTSWMolBiol 30th anniversary celebration: bit.ly/4bAh20V
Today #NIH is terminating more than $250 million in funding—including more than 400 grants—to Columbia University following directives from the Trump Administration’s Joint Task Force to Combat Anti-Semitism. The cancellations are due to Columbia University’s continued inaction…
Mouse created using embryonic #stemcell engineering from two male parents lives until adulthood. Learn more in @CellStemCell cell.com/cell-stem-cell… #ChineseAcademyofSciences Guan-zheng Luo, Qi Zhou, & Wei Li
With pleasure we share our preprint reporting robust and cost-effective expansion of naive human Pluripotent Stem Cells without feeder cells. A fantastic collaborative effort with @leeboratory @JZylicz @vincentpasque @Nrivron tinyurl.com/5n6z9rt9
Next Generation Stem Cell Researchers: Join us and take your chance to present by submitting an abstract!
The deadline to submit an abstract for a talk in the 2025 SY-Stem symposium ends today! SY-Stem - a symposium focusing on the next generation of stem cell researchers - is organized by IMBA and the @IMPvienna. Register here: bit.ly/SYstem2025
An interesting study from Mia Yang's lab suggesting that chromosomal instability may be an intrinsic characteristic of placental development! biorxiv.org/content/10.110…
This is wild! Congrats @pdhsu
Today we report Evo, a generalist foundation model for biology, on the cover of @ScienceMagazine. Trained on billions of DNA nucleotides, Evo was designed to capture two key aspects of biology: the multi-modality of the central dogma and the multi-scale nature of evolution.
Happy to share our latest paper, a reference atlas of human development from zygote to gastrulation. Further developed an online reference tool to call cell lineages in an easy and automated manner. Fantastic work by @ChengZh71215605 and authors nature.com/articles/s4159…
Thank you! Had a great time in Adelaide! One of my favorite places :-)
What a privilege to see @leo_jwu present all of his latest implantation and gastrulation models in person! Incredible work 🤯💥 #ASSCR2024
Thank you for the invitation and too bad I had to leave before the photoshoot. Really enjoyed my time there and discussions with faculty members and trainees!
A huge thank you to our guest speakers and all attendees for making this year's Greenwald Symposium a huge success! @chavezs27 @dmonsi312 @leo_jwu @DukeCellBiology @WSUvetmed @OMRF @HKowash @bmichellej87 @MikiSimon_ @ArturoM_V
Interesting work! 👉 Shifts in embryonic oxygen levels cue heterochrony in limb initiation | bioRxiv biorxiv.org/content/10.110…