Liang-Bo Wang
@lbwang2
Scientist, Oncology Bioinformatics at @moderna_tx. PhD in Computational and Systems Biology from @WUSTLdbbs. Genomics 🤘.
Finally sharing this collaborative work with my amazing labmates Avi and Siqi! We asked how chromosome position and cellular environments impact gene expression noise by developing a new single-cell method (with a genomicsy name just because) 😉 biorxiv.org/content/10.110…
Today Cell, Cancer Cell and Cell Reports Medicine are pleased to publish the 1st wave of Pan-#Cancer multiomics papers looking at over 1000 patients across 10 #tumor types from @theNCI Clinical Proteomic Tumor Analysis Consortium #CPTAC (1/n) @Cancer_Cell @CellRepMed #openaccess
We are excited to announce a collection of new human reference genome sequences that reflect much more global diversity! nature.com/articles/s4158…
webR v0.1.0 has just been released! I'm super excited to see what people create by using webR in their own projects 😃. The docs are at docs.r-wasm.org and I've written an introductory blog post talking more about the kind of things webR can do at tidyverse.org/blog/2023/03/w….
english.cw.com.tw/article/articl… Thanks to Commonwealth Magazine @CWM_en for publishing a summary version of my article detailing my experience of becoming a Taiwanese citizen as a Taiwan Gold Card holder. Please share it forward to those who may benefit from it. Thank you
Our single-cell MPRA paper is finally out! Super excited about the potential of this technology to study cell-type specific gene regulation 🥰
Out today in @NatureGenet, our group’s single-cell MPRA technology for testing activities of gene regulatory elements in whole tissues. Congrats to Siqi Zhao and the rest of the crew for their great work! nature.com/articles/s4158…
We are delighted to share our work, now available in @Nature: nature.com/articles/s4158… Our scoring system can be accessed here: kinase-library.phosphosite.org Coming soon --> the tyrosine kinome and an improved system with many new functionalities & features! #TheKinaseLibrary #KL
Our paper on insulators is out on Biorxiv! We tested the activity of insulators across thousands of genomic locations to figure out where insulators function. Oh, and I successfully defended today :) biorxiv.org/content/10.110…
I designed this cover for my PhD thesis using #DALL-E and #StableDiffusion, I'm quite happy with the result! Took a few steps to combine the strengths of both engines, I found SD: beautiful images, DALLE: gets the story right; look at the steps below: (1/5+2)
After more than two years of working on this project, we are delighted to share our effort in harmonizing the tumor microenvironment (TME) of glioblastoma (GB) at single-cell resolution and providing insights into the tumor architecture (biorxiv.org/cgi/content/sh…). Details 🧵👇🏼 1/N
‼️ ONLINE NOW @NatureGenet 📰 Spatially restricted drivers and transitional cell populations cooperate with the microenvironment in untreated and chemo-resistant pancreatic cancer 🧑🏾🤝🧑🏻 Li Ding @reykajayasinghe @DeNardoLabWUSM and colleagues ⬇️ go.nature.com/3AEvt3n
There are different versions of the human genome annotation but which do you use? The Matched Annotation from @NCBI and EMBL-EBI (MANE) collaboration is the answer and brings new meaning to the phrase: two heads are better than one. ebi.ac.uk/about/news/res…