Lorand Kis
@kis_lorand
pathologist; molpat, IHC, no favorite organ (yet); tweets are not medical advices, cases for educational purpose only
HER2-positive invasive breast carcinoma (NST). HER2 gene-protein assay: brightfield tricolor assay (combined ICH+ISH) for the visualization of HER2 protein (brown), the HER2 gene (black), and chromosome 17 centromere (CEN17) (red).



This was a fun project - OSET is a novel soft tissue tumor we discovered recently via careful raddiolgy, histologic and IHC correlation - only much later did we discover its molecular signature - most harbor recurrent SRSF7::NFATC3 fusions and OSET has a unique epigenetic…
Ossifying Spindled and Epithelioid Tumor: A Novel Soft Tissue Tumor | @ModernPathology @JMcMahonG @jonathandudley @LisaRooperMD @PeterArgani sciencedirect.com/science/articl…
🚨 ISUP Presents..... 🔬Dr. Mahmut Akgul on “High Grade Primary Kidney Tumors: The Ugly Five” 📅 14 Aug 2025 at 12 pm EST via Zoom Register here: us06web.zoom.us/webinar/regist…
81 y.o. M, cystectomy specimen. What is your diagnosis? #PathTwitter @MGBpathology @MGHPathology
Sialoliths of the submandibular gland. 80-90% of sialolithiasis cases. Why? ▪️ Thick, mucin-rich saliva ▪️ Long, ascending Wharton's duct ▪️ High calcium concentration 🔬 🔻 Atrophied acini 🔻 Dilated ducts 🔻 Periductal fibrosis 🔻 Chronic infiltrate #PathTwitter #ENT #OralPath
What is your diagnosis? 5 WSI to help you reach your conclusion. kikoxp.com/posts/60881
Axillary lymph node. What is your diagnosis? 🔎 Stain clues and poll below 🗳️👇 #PathPuzzle 🕵️♂️ @KMirza @UMichPath #Pathology #PathX #PathTwitter
florid #GUpath example of bladder TURBT spectrum showing: cystitis cystica➡️cystitis glandularis➡️CCG with intestinal metaplasia
CAP TODAY @Pathologists and the Association for Molecular Pathology @AMPath have teamed up to bring molecular case reports to CAP TODAY readers. 🚨💡Check out our case report in CAP TODAY, and test yourself at the end: Identifying the signal in the signal: incidental detection…
What’s this lesion of the breast? 🔬 Poll in the comments 👇 Answer to be posted on Monday #PathX #PathTwitter #breastpath #histology #PathQuiz
Papillary lesion of Breast, lump excision in 38/F. #Breastpath #Surgpath #PathX #Pathtwitter #Pathology #Pathresidents #Pathologists
Suprasellar/hypothalamic mass with a PRKCA mutation. Diagnosis? (I'll strum a few CHORDs on my guitar while you think about it.) #pathology #neuropath #pathtwitter
Case of Nipple Adenoma 🔬 Nipple adenoma is a benign proliferative epithelial process of the superficial lactiferous ducts that may erode the overlying squamous epithelium. #PathX #PathTwitter #breastpath
Check out our new paper on Papillary Neoplasms of the Breast! Includes WHO Classification, Multimodality Imaging, and Radiologic-Pathologic Correlation in RadioGraphics😁 pubs.rsna.org/doi/10.1148/rg… #breastpath #radpath #pathX #PathTwitter #pathresidents #papilloma
Case of Tubular Adenoma of Breast🔬 Tubular adenoma of breast is a benign mass composed of densely-packed round ductules with limited intervening stroma. No relation to the colon! #PathX #PathTwitter #breastpath
Quick quiz! 🧠 You’re reviewing this testicular tumor from a 32 yo patient. What's your diagnosis? 👇 #PathTwitter #GUPath #MedEd
Mini #tweetorial for anyone who wants to learn how to do a good PowerPoint presentation: Tip 1: Look and sound bored. Sigh a lot.
Kudos to those who educate others selflessly
📣 Each month, our team of screening judges selects a standout tweet from the trainee category for the #PathTweetAward. 📅 For June 2025, the winner is: 🏆 @whosainastro 👏 Congratulations on making an impact across #PathTwitter!
What is this crystal called? Which tumour is it associated with? #pathtwitter #pathresidents #dermpath #BSTpath #GIpath #ENTpath