Craig Horbinski
@CraigHorbinski
Director of #Neuropathology, Nervous System Tumor Bank, and Path Core at #Northwestern. My #NIH-funded laboratory studies #glioma and #meningioma.
Ever wonder exactly WHY #glioblastoma is so fatal, relative to other #cancers? Check out our new article on the subject. academic.oup.com/neuro-oncology…
#neuropath isn't just tumors, it's a lot of things. Like trauma. Here's a cluster of anterior horn spinal neurons undergoing central chromatolysis in response to axonal injury, wherein the neurons upregulate protein synthesis to facilitate axon regrowth. #PathTwitter #pathology
IDH-wildtype astrocytoma with FH mutation, epigenetic similarity to IDH-mutant astrocytoma, and hypermethylation of CDKN2A arising in the brainstem #neuropath academic.oup.com/jnen/advance-a…
Pretty brisk giant cell reaction in a sacrococcygeal #teratoma. #pathology #neuropath #PathTwitter
Nice example of an epidermal inclusion cyst right next to cerebellar cortex in the posterior fossa. #pathology #neuropath #pathtwitter
Impressive CAM5.2-positive fibrous bodies in a sparsely granulated PIT-1 pituitary adenoma (a.k.a. PitNET). If you look carefully, you can see them on the corresponding H&E. #pathology #neuropath #pathtwitter
Metaplastic transformation of a #glioblastoma is relatively uncommon, but when it happens it's striking. Like this case, where the #GBM is transforming into bone. #pathology #neuropath #pathtwitter
Multiple intracerebral ring-enhancing lesions. Diagnosis? (These images are so good, they might make HISTOry.😁) #pathology #neuropath #PathTwitter
The U.S.’s dramatic research and funding cuts as well as changes to skilled-worker immigration policies threaten one of its greatest economic advantages: people-powered innovation wsj.com/politics/polic… via @WSJ
Check out Dr. Brat’s feature in The Pathologist where he reflects on his career as a neuropathologist and gives advice to those considering the specialty. @DanielJBrat @pathologistmag thepathologist.com/issues/2025/ar…
Research by senior author Stephen T. Magill, MD, PhD published in @JclinicalInvest, indicates that a medication typically used for treating Type 2 diabetes may help reduce excess fluid in the brains of patients with #hydrocephalus. Read more now: news.feinberg.northwestern.edu/2025/06/26/dia…