Karel Kieslich

In this new preprint we ask: What drives #anhedonia? Problems with experiencing pleasure, reward valuation, or reward learning? @jonroiser, @vincentvalton and I reviewed the evidence from mostly cross-sectional studies in depression and schizophrenia psyarxiv.com/cya6r 🧵1/

I've never been one to shy away from new/unusual ideas, and at the start of my postdoc, I stumbled across an interesting question: Why is there substantial comorbidity between depression and type-2 diabetes? (x2 risk of developing one if you already have the other) The answer?

Just concluded our 2024 UCL-Wellcome Mental Health Science PhD Retreat with all four cohorts! Huge gratitude to @wellcometrust & @ucl for their unwavering support throughout our PhD journeys! 🧠

Stopping antidepressants increases the risk of relapsing into depression. We don't know the underlying mechanisms of why this happens. Nor do we know who will be fine and who will relapse after stopping antidepressants. As part of the AIDA study, we tested people before and after

This. Every day that supporters delay their assistance to Ukraine is another day that Russia has to dig in, fortify its defenses and regroup for more attacks — not to mention another day where lives are lost and homes and families are destroyed.

in the oven since before Covid (!), our paper on effort-based decision making for reward in depression, interrogated using rigorous computational analysis by @vincentvalton, HAS ARRIVED! See @AnahitMkr's excllent🧵for details👇, and of course the preprint biorxiv.org/content/10.110…

✨New preprint out✨ We examined motivational dysfunction in depression, aiming to dissect which cognitive processes drive impaired effort-based decision making. Through an extensive computational analysis - by the expert @vincentvalton🧠💫- we find a somewhat surprising answer👇

Russia’s use of chemical weapons against Ukrainian soldiers should be a much bigger international news story. My friend and colleague @JimmySecUK has a sobering piece on this here: telegraph.co.uk/world-news/202…

We live in a time increasingly resembling the second half of the 1930s. I couldn't live with myself with the knowledge I didn't do more to stop another Hitler. In light of the Republican wavering and in memory of Navalny I will give $100 towards FPV drones for Ukr for every RT.

We are now recruiting for the fifth (and sadly, final) cohort of the UCL-Wellcome 4-year PhD in Mental Health Science, closing date 10th January. For more info, including videos of our online "Roadshows", see our "How to apply" page ucl.ac.uk/mental-health/…

Important to realise that what Ukraine is up against isn't just a normal army, but the legacy capabilities of a global superpower that spent decades preparing for WWIII. They're incompetently used by Russia and attrited by Ukraine, but there is still a lot of stuff that kills.

Great to have this now out and freely accessible in @AnnualReviews ! annualreviews.org/doi/pdf/10.114…

🚨This year will be the FINAL CHANCE to apply for the UCL-Wellcome 4-year PhD in Mental Health Science🚨(details in below thread). On October 10th we're running an online Q&A session for applicants with committee members and current students, register here eventbrite.com/e/qa-session-u…

Imagine somebody publishing a book named "I love the Third Reich" in Britain in 1941 and promoting it using the words like "An intimate portrait of Reich, and a passionate cri de cœur for journalism".