JAMA Psychiatry

Systematic review and meta-analysis: Stopping antidepressants leads to slight symptom increases compared to placebo, but these symptoms are not clinically significant and do not include mood changes. ja.ma/4eI7oeo

Most viewed this week from @JAMAPsych: Systematic review and meta-analysis: Stopping antidepressants leads to slight symptom increases compared to placebo, but these symptoms are not clinically significant and do not include mood changes. ja.ma/40fpWg6

Most viewed this week from @JAMAPsych: Systematic review and meta-analysis: Stopping antidepressants leads to slight symptom increases compared to placebo, but these symptoms are not clinically significant and do not include mood changes. ja.ma/3IGmK72

From @JAMA_current: Remote, scalable cognitive behavioral therapy–based chronic pain programs are effective for treating individuals with high-impact chronic pain. ja.ma/46qkVVQ

Viewpoint: Amid financial constraints, prioritizing @VeteransHealth mental health research is essential for addressing the unique mental health needs of veterans and to improve evidence-based treatments. ja.ma/4lGduhY

Early maternal warmth positively influences adolescent health by enhancing perceptions of social safety. ja.ma/4kDtSyJ @UCLAStressLab

Most viewed this week from @JAMAPsych: ADHD medications are consistently associated with reduced risks of self-harm, unintentional injury, traffic crashes, and crime, but these protective effects weakened as prescription rates increased. ja.ma/3TN8dsU

Antipsychotic treatment effectiveness was similar regardless of recent treatment, but those not recently treated had better overall outcomes with both antipsychotic and placebo treatments. ja.ma/3Ibl05S

Viewpoint: Target trial emulation can improve observational study validity by applying randomized trial design principles, but it is not a substitute for randomization. ja.ma/3TlrVM8

Distinct brain abnormalities were found in the subgenual anterior cingulate cortex, amygdala, and hippocampus in long-term sleep disorders, and in the right thalamus following short-term sleep deprivation. ja.ma/4kiU1m8 @MasoudTahmasian

Most viewed this week from @JAMAPsych: ADHD medications are consistently associated with reduced risks of self-harm, unintentional injury, traffic crashes, and crime, but these protective effects weakened as prescription rates increased. ja.ma/3ISDpV5

Viewpoint: Patients with psychotic conditions often wish to stop antipsychotics, suggesting a shift to shared deliberation for collaborative management of associated risks. ja.ma/4kS5PMA

"There is an urgent need for research on strategies to manage psychiatric disorders associated with restricted reproductive health services." Learn more in this Special Communication. ja.ma/4kGFSPG @appelbap @ibzpsychphd

RCT: Older adults with #insomnia have an increased vulnerability to depressive mood and symptoms following inflammatory exposure. ja.ma/3TIXVtG

In older adults, discontinuing antipsychotic medications after hospitalization was associated with reduced risks of rehospitalization, falls, infections, delirium, and mortality compared to continuation. ja.ma/40y37nO

This meta-analysis identified gaps in the reporting and representation of race and ethnicity in mental disorder pharmacotherapy trials. ja.ma/4ewJTF6 @AlessioBellato @dtleffa

This Special Communication proposes a cross-species framework in behavioral neuroscience to study emotional well-being and brain aging in the context of Alzheimer disease. ja.ma/4eBezoG

Viewpoint: Medicaid 1115 waivers need reforms to enhance mental health care by eliminating stay limits, promoting comprehensive care, streamlining processes, and focusing on early intervention and integration. ja.ma/4nDbtVl

This narrative review discusses the uncertainties, challenges, and specific areas of novel research in the growing field of inflammation and adult psychiatric disorders. ja.ma/40AN9cI