Harlan Krumholz
@hmkyale
Harold H. Hines Jr Professor, Yale Univ; Director, YNHH CORE; Editor-in-Chief, JACC. Working to improve the future for those who follow us...
We are underestimating the downside of our current system when we contemplate change. We need to take some risks to do better. #abimf2013
We’re not short on tools—we’re short on action. This bold editorial says we’re at the prevention tipping point. Will we cross it? 🤔🫀 jacc.org/doi/10.1016/j.… #JACC #cvPrev @hmkyale
🎙️ New JACC Deep Dive: Why did ACURATE neo2 fail in the IDE trial? Post hoc analysis suggests valve underexpansion may be part of the answer. Even with normal gradients. Even with good echo. We explore what happened—and what’s next. 🔗 jacc.org/digital-conten… @JACCJournals
🎧 New #JACC This Week podcast 🔬 Valve underexpansion & outcomes in ACURATE IDE 💉 Body composition & tirzepatide in HFpEF 🏥 Private equity & heart failure care 🫀 Multivalve dz challenges 🧾 Brief reports+more ▶️Listen: jacc.org/digital-conten… #cardiotwitter @JACCJournals
🇪🇸:締切まであと1週間‼️ ESCでのSimpub目指してみませんか? 完成した論文をぜひJACCへご投稿ください。 初稿についてはフォーマット問いません。 👉jacc.org/journal/jacc/a… @JACCJournals @ACCinTouch #SimPub #ESC #JACCばらん
🇪🇸ESC に採択されたその演題、JACCに投稿してみませんか? 目指せ#Simpub‼️〆切は8月1日まで @JACCJournals @hmkyale #ESC2025 #Madrid
New Health & Veritas drops tomorrow! We’re joined by the incredible @dr_kkjetelina — epidemiologist, science communicator, & author of Your Local Epidemiologist. We talk public health, trust, & art of translating science for millions. @thehowie @YaleSPH @YaleSOM Don’t miss it.

So true. Windsurf and others are really bad examples of founders leaving their teams behind and not even sharing the proceeds with their team. I definitely would not work with their founders next time.
“There's an unspoken covenant that as a founder, you go down with the ship. For better or worse, it's changed a bit over the last year and I think it's disappointing, to be honest.” Enough said. This show is everything and more on: - What really happened behind the scenes -…
In this episode of #JACC This Week, Editor-in-Chief Dr. Harlan Krumholz introduces the journal’s new design and highlights key studies from this week's issue. 🎧 Listen here or wherever you get your podcasts jacc.org/digital-conten… #JACCJournals #JACCPodcast @hmkyale
In @NatureCVR, our @cards_lab study defines a new approach to identifying adults w hypertrophic cardiomyopathy (HCM) - a leading cause of cardiac arrest in young adults Using #AI_ECG for images/photos of ECG (📸) Led by ⭐️s @veer_sangha_ @LovedeepDhingra…
🧵1/Today, we published a key milestone towards AI based cardiac screening in Nature. doi.org/10.1038/s41586… EchoNext outperformed cardiologists and found thousands of high-risk patients missed in routine care. We also made a version available to the world.
“CV Prevention is in reach but only w/ implementation that’s global, upstream, and grounded in data.” In this week’s #JACCThisWeek, I highlight Focus Issue on Prevention: polypills, syndemics, PREVENT, inclisiran, and more. @jaccjournals 🎧 Listen here: jacc.org/digital-conten…
An #AI system that automatically interprets echocardiograms maintained high accuracy across geography and time from complete and limited studies. @rohan_khera ja.ma/45zhTye
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NY Times editorials have greater narrative strength than science and medicine, BUT the editorials of @jeremyfaust are more powerful than all of them. We’ve never seen such narrative strength. Article in the comments.
Long-term exposure to #wildfire smoke-related fine particulate matter was linked to a higher risk of HF in older adults compared with non-wildfire smoke PM2.5. Furthermore, women & socially vulnerable populations were more susceptible. jacc.org/doi/10.1016/j.… #JACC #AirPollution
Excited that #PanEcho is now published in @JAMA_current Kudos to @giholste @ekoikonomou for leading this incredible effort! Now also validated on ED POCUS studies + RVNet+ (Thx Attila Kovacs & Marton Tokodi for joining us) See 🧵 below for details! jamanetwork.com/journals/jama/……
After 2 months of embargo for #AHA24 Late Breaking presentation, we are pleased to announce PanEcho - Complete AI-enabled echocardiography interpretation with multi-task deep learning Led by @giholste & @ekoikonomou @cards_lab Preprint, code, model here:…
There are few in this world who were such forces for good as @atulbutte. His dazzling intellect, relentless curiosity, generosity of spirit, boundless charisma, and infinite optimism left a mark on everything he touched and everyone lucky enough to know him. An enormous loss.
"High-risk plaque,” not “vulnerable plaque”? This new #JACCIMG statement explores challenges to the concept, advances in imaging & therapy, and the future of focal interventions. jacc.org/doi/10.1016/j.… @ron_waksman @GreggWStone @RoccoVergallo
In divided times, #HealthCare must lead—not watch. Dr. Harlan Krumholz (@hmkyale) calls on medicine to be a bridge, not a wall in his latest #JACC editorial. 🩺 The time for courage is now. 🔗 ow.ly/SIkt50VRO4i #CardioX #HealthcareLeadership
In @JACCJournals, we find that heart failure outcomes didn't change after hospitals were acquired by private equity, despite admitting ⬇️ risk patients & ⬆ cardiac procedures. Transfer-outs doubled for Black adults Presented at #ARM25 @danielyjohnson bit.ly/43Z3NDS