Superti-Furga Lab
@gsf_lab
Official account of the Superti-Furga Lab at CeMM
Out from the GSF lab in between the years: "Ex vivo imaging-based high content phenotyping of patients with rheumatoid arthritis (RA)" by PhD student and MD Felix Kartnig and with @leoheinz et al. See the study on immunophenotypic characterization of RA at sciencedirect.com/science/articl…
🧠 Mutations in the #SLC13A5 gene disrupt citrate transport in neurons, causing severe #epilepsy. In a new study published in @ScienceAdvances, CeMM researchers uncover the molecular mechanisms behind this disease. ➡️ Info: bit.ly/3T4u12N 🔗Study: bit.ly/3HRy8wR
Congratulations to Sophie Piech from the group of CeMM Scientific Director Giulio Superti-Furga (@gsf_lab), who has successfully defended her PhD thesis entitled "Chemical modulation of CUL3LZTR1-mediated proteostatic RAS regulation." Well done!! 🎓 👏 🎉 #phdlife #phdhat
Paper(s) alert from our @RESOLUTE_IMI project – In a compilation of four papers in Molecular Systems Biology we show how we were deciphering cellular logistics and present a comprehensive systematic blueprint of chemical transport pathways with #SoluteCarrier transporters
Join us for groundbreaking science at the Keystone Symposium on Solute Carrier Transporters this April 2026 in Beverly, MA, USA! 🌟 Hosted by @giuliosf, David Drew, and Kathleen M. Giacomini. Save the date—keysym.us/KSSoluteCTs26 #KSSoluteCTs26 #solutecarriertransporters
The @gsf_lab at CeMM studies #MembraneTransporters & their roles in metabolism, drug transport & signaling. In this #EquationsForLife story, they use the #NernstEquation to better understand the electrochemical forces involved in membrane transport. 🔎 tinyurl.com/CeMMRR2024-GSu…
We warmly welcome the life science community @viennabiocenter @IMPvienna @IMBA_Vienna @MaxPerutzLabs @GMIvienna @ISTAustria @StAnna_CCRI @MedUni_Wien to the 2025 #CeMMLandsteinerLecture with Tony Wyss-Coray! 📅 May 12, 6PM | Austrian Academy of Sciences 🔗 cemm.at/landsteiner-le…
Cold but fun. Fast as usual... ;-) #TogetherWeRun with two teams of GSFies at the Relay @Vienna_Marathon 2025. 🏅🏅🏅
17 CeMM Teams = 68 CeMMies and Adjunct members participated at the Vienna City Relay Marathon 2025 @Vienna_Marathon, and reached 717,4 km in total. Congrats also to our friends from @StAnna_CCRI! 👏 photo gallery: bit.ly/4j4ultM #VCM #ViennaCityMarathon #TogetherWeRun
Collaborating within @RESOLUTE_IMI and REsolution we characterized 21 variants of hSLC39A8 (ZIP8), a metal transporter. Revealing diverse impacts on localization, ion uptake & stability—shedding light on disease mechanisms. life-science-alliance.org/content/8/4/e2…
Within @RESOLUTE_IMI and REsolution the @gsf_lab at @CeMM_News studied variants of the human SLC39A8 (ZIP8) metal transporter better understanding links to diseases involving disrupted metal ion homeostasis life-science-alliance.org/content/8/4/e2…
CeMM members had a great time at the Vienna Science Ball 2025 - Wiener Ball der Wissenschaften! Congratulations to Oliver Lehmann and the ball organizing team for a successful #SciBall25 and a wonderful 10th Anniversary! bit.ly/4gfxV1C
Celebrating Science with style at the #Vienna Ball of Sciences. The GSF Lab of @CeMM_News beautifully dressed in the beautiful Vienna City Hall. 💃🕺💃🕺
🔬 Applied #PrecisionMedicine: High-tech microscopy could enhance #rheumatology therapies! CeMM & @MedUni_Wien developed a method to predict individually the best drug for rheumatoid arthritis using blood samples ➡️ Info: bit.ly/42lZIdu ➡️ Study: bit.ly/40GXB2Q
Kicking off the new year properly: In collaboration between the labs of @giuliosf and @alessiociulli we found that the efflux pump ABCC1/MRP1 constitutively restricts PROTAC sensitivity in cancer cells. Out in @CellChemBiol cell.com/cell-chemical-…
Happy New Year from the GSF Lab. 🎇(And Merry (late) Christmas.🎄) This year we send greetings from our Karaoke evening - with poems and Secret Santa. To successful science in 2025! 2⃣0⃣2⃣5⃣
A paper from @cemm_news, @gsf_lab, @AndreFerdigg, and @giuliosf employs loss- and gain-of-function genetic screens to unravel the role of membrane transporters in controlling heavy metal toxicity in human cells. life-science-alliance.org/content/8/2/e2…
New article in @LSAjournal on #SLC transporters in metal toxicity. PhD student @AndreFerdigg et al found: MRP1/ABCC1 protects against arsenic and mercury; SLC39A14 and SLC30A1 sensitize for cadmium; interestingly SLC30A1 modulates Cd toxicity through zinc doi.org/10.26508/lsa.2…
Hear Superti-Furga lab member @FabianFrommelt on our recent SLC-interactome preprint (doi.org/10.1101/2024.0…) at #HUPO2024 in Dresden on Oct 21. And discuss with him his previously published DIP-MS method (doi.org/10.1038/s41592…) at poster session III (poster: 0880, Oct 23).
Just a few more minutes until hearing about metabolism linking to the environment at the lecture of @giuliosf at the #RiMED Foundation symposium "Nutrition, Microbiome, Metabolism" #RiMED2024 in Palermo, Sicily today. The GSF lab's and @RESOLUTE_IMI endeavors on #SLC transporters
Are you curious what is known about SLCs? And how they are related? We are enthusiastic to wrap up the series of four (4) manuscripts by presenting the data- and knowledge-derived functional landscape of human solute carriers #SLC : biorxiv.org/content/10.110…
We are thrilled to share the THIRD study of our series which sheds light on the genetic interactions between transporters and links them to the metabolic network: doi.org/10.1101/2024.1…