Giordano de Guglielmo
@giodeguglielmo
Assistant Professor at UC San Diego.
Helping my son Leonardo with his Wildcat Run Fundraiser getmovinfundhub.com/student-webpag…
Exciting #sfn2024 presentations from the de Guglielmo lab today, 1-5 PM! @m_r_doyle (O25) & Dr. Wood (O24) showcasing our preclinical #GWAS in rat models of alcohol dependence. Behavioral phenotyping hundreds of rats & exploring individual medication responses based on novel…

I'm excited to share another piece from my PhD - and start of my postdoc! Based on our previous study refining heroin self-administration, we propose a choice procedure to identify individual differences in preference for heroin and social interaction. bpspubs.onlinelibrary.wiley.com/doi/10.1111/bp…
#ThisWeekInNPP #Cannabidiol (CBD) ⬇️ alcohol consumption & withdrawal in 🐀 by normalizing BLA excitability & protecting striatal neurons - a promising step toward innovative #AUD treatments #Neuroprotection #AddictionResearch // @giodeguglielmo nature.com/articles/s4138…
Excited to share our latest paper in @npp_journal! Chronic CBD mitigates alcohol dependence, reduces withdrawal symptoms, & offers neuroprotection in BLA & striatum in rat AUD models. Congrats to 1st author @neuroselo! Thanks to @cmcr_ucsd funding for the pilot that sparked this.…
Thrilled to share our latest paper in Neuropharmacology in collaboration with the @TeleseFrancesca and @AbePalmer Labs at @PsychiatryUcsd. We explored how perinatal fentanyl exposure promotes persistent addiction vulnerability and alters gene expression in the central amygdala…
True 👇
One reason for public distrust in science? For the last 15 years academic leaders have been advised to limit public engagement—stay off social media, avoid controversy, it’s too risky for the institutions.
Amazing week with family and colleagues at @ACNPorg
Thank you @ACNPorg for another exceptional meeting! Appreciate your family-friendly approach, blending science & quality time seamlessly #ACNP2024
Congratulations to @CodySiciliano for winning the @ACNPorg #NEECA award!!
Happy to be part of this program
Please join us in congratulating the selected mentors and mentees for the 2025 URM Near-Peer Mentorship Program! More info: bit.ly/4euV2Vi
Excited to share our latest @eLife pub, 7 years into the making. This study highlights the critical need to understand individual differences in addiction research. And this is just the beginning, stay tuned for upcoming stories applying this approach to alcohol and opioids
Does Drug Intake Despite Adverse Consequences Really Measure Compulsivity? There’s a big debate in addiction research: is drug use despite adverse consequences (like punishment) a standalone measure of compulsive behavior, or just part of a larger addiction profile? This new…
People often ask why I want a big lab. Truth is, I don’t-it’d be easier smaller. But how could I turn away a student with dreams of science? Running a big lab means more grants, more work, less time with family/friends. But seeing students grow as scientists makes it all worth it

🐀 Please RT 🐀 RATTACA is back at #SfN24 — come see us tomorrow at Booth #1828. RATTACA uses polygenic risk scores to predict behavioral traits in outbred rats. Now you can study genetic predisposition to substance abuse in drug naive rats! Details at ratgenes.org/rattaca
The Center for GWAS in outbred rats (ratgenes.org) has a booth at #SfN22 (#3229). We are offering outbred rats with *genetically predicted* behavioral and physiological phenotypes. It's like selected lines, but we can predict for dozens of traits. What traits? Read on.
Today, we bid farewell to our amazing @neuroselo , as she embarks on her Ph.D. journey at @UCIrvine ! You'll be deeply missed, but we can't wait to see the incredible things you'll achieve next! #FarewellSelen #deguglielmolab @PsychiatryUcsd

Time to wrap up #IDARS2024. Wonderful week in Rio catching up with friends and colleagues. A special thanks to @The_Gilp and @touchyourbrain for putting together a great meeting

Looking forward to this one!
🔥Panel announcement🔥 Of Mice and Men: The Role of Opioids on Affect & Reward. Don't wanna miss our fantastic speakers @EDarcq, @ginevradottavio, @giodeguglielmo, and @sirileknes!!