Enzyme Chemistry
@EnzymeChemistry
@SoufianTibouti thinks Nature is the ultimate chemist.
Enzymatic Basis of Stereochemical Control in Reserpine #Biosynthesis by Jiaqing Cao, Jingxiao Zhong, Feng Li, and @JiangYindi in @J_A_C_S pubs.acs.org/doi/10.1021/ja…
Copper-Dependent Hydroxylation Catalyzed by the DUF3328 #Enzyme CctR by Kaushik Seshadri, Chen-Yu Chiang, Kyle K. Nagasawa, and @yitang_ucla at @uclachem in @J_A_C_S pubs.acs.org/doi/10.1021/ac…
#Enzymatic Stereodivergent Synthesis of Azaspiro[2.y]alkanes by Jennifer L. Kennemur, Yueming Long, Catherine J. Ko, Anuvab Das, and @francesarnold at @CaltechCCE in @J_A_C_S pubs.acs.org/doi/10.1021/ja…
![EnzymeChemistry's tweet image. #Enzymatic Stereodivergent Synthesis of Azaspiro[2.y]alkanes by Jennifer L. Kennemur, Yueming Long, Catherine J. Ko, Anuvab Das, and @francesarnold at @CaltechCCE in @J_A_C_S pubs.acs.org/doi/10.1021/ja…](https://pbs.twimg.com/media/GwexOMnXUAMZNYb.jpg)
Terminal Carboxyl Editing Drives Divergence in Fasamycin and Anthrabenzoxocinone #Biosynthesis by Kai Jiang, Cheng Zhu, Yan Gao, Yuhan Dai, Xiaoli Yan, Lu Yang, Ming Jiang, Zhi Lin, Zixin Deng, Shukun Luo, and Xudong Qu in @J_A_C_S pubs.acs.org/doi/10.1021/ja…
Structure and Mechanism of the Azomycin #BiosyntheticEnzyme RohQ That Catalyzes a Spontaneous Cyclodehydration by Zi-Wang Wei, Phillip Daniel-Ivad, Li Zhang, and Katherine S. Ryan at @UBCChem in @J_A_C_S pubs.acs.org/doi/10.1021/ja…
Steering oxygen-centred radicals with ground-state ene-reductases for enantioselective intermolecular hydroalkoxylations by Bin Chen, Qiaoyu Zhang, Jinhai Yu, Beibei Zhao, Ran Ge, Zihan Zhang, Ding Luo, Binju Wang, and @huangx513 in @NatureCatalysis nature.com/articles/s4192…
Unlocking Lewis acid catalysis in non-haem #enzymes for an abiotic ene rxn by Xinpeng Mu, Xinyuan Ji, Xiahe Chen, Hongli Wu,Jinyan Rui,Xin Hong,Madison Worth, Abigail Reitz,Lucie Goldberg, @MarcGBQ, Sarah Michel, Yunfang Yang, @xiongyih in @NatureCatalysis nature.com/articles/s4192…
Ketosynthase Domain Catalyzes β-Lactonization in the #Biosynthesis of the HMG-CoA Synthase Inhibitor Hymeglusin by Mizuki Hirokawa, Taro Ozaki, Kento Tsukada, Akihiro Sugawara, Yohei Morishita, and Teigo Asai in @J_A_C_S pubs.acs.org/doi/10.1021/ja…
Nucleophilic α-Functionalization of Benzyl Amines Using an Engineered Threonine #Aldolase by Yao Ouyang, Suhao Wang, Damien Sorigue, and Todd K. Hyster at @PrincetonChem in @J_A_C_S pubs.acs.org/doi/10.1021/ja…
Profiling of Diverse Pyridoxal-5′-Phosphate Dependent #Enzymes by Kendrick Smith, Madeline Arbuckle, Alexander Kim, Chun-Yi Tsai, John McIntosh, Deeptak Verma, @EunjaeShim1, Alison Narayan @NarayanLab @MichiganChem in @J_A_C_S pubs.acs.org/doi/10.1021/ja…
A Carbamoyl N-Methyltransferase Catalyzes N-Methylation of the Primary Amide in Ansacarbamitocin #Biosynthesis by Zhongyue Li, Wanting Yang, Zhonglin Sun, Haoxin Wang, Chunhua Lu, Deyu Zhu, Yuemao Shen in @J_A_C_S pubs.acs.org/doi/10.1021/ja…
#Enzymatic Stereoselective Nucleophilic Cyclization Governs Atypical Spirotetronate Assembly in Lucensimycin A #Biosynthesis by Meng Yu Xi, Bo Zhang, Ting Peng, Xiu Xiu Ma, Ao Zhu, Zi Jie Wang, Yucheng Gu, Ren Xiang Tan, @huiming_nanjing in @J_A_C_S pubs.acs.org/doi/10.1021/ja…
#Biosynthesis of Biphenomycin-like Macrocyclic Peptides by Formation & Cross-Linking of Ortho-Tyrosines by Chandrashekhar Padhi, Lingyang Zhu, Jeff Chen, Chuan Huang, Ryan Moreira, @Challis_Group, Max Cryle, Wilfred van der Donk @ChemistryUIUC in @J_A_C_S pubs.acs.org/doi/10.1021/ja…
Structural Basis for Dehydrogenase/Reductase-Catalyzed Reductive Cyclization in Polycyclic Tetramate Macrolactam #Biosynthesis by Xiangqian Xie,Fan Li, Yanxin Mu, Mengyao Lu, Jie Luo, Haoxin Wang, Yuemao Shen, Liangcheng Du, Deyu Zhu, Yaoyao Li in @J_A_C_S pubs.acs.org/doi/10.1021/ja…
Discovery of acylsulfenic acid-featuring natural product sulfenicin & characterization of its #biosynthesis by Xue, Zou, Qiu, Lv, Madden, Xu, Lian, Pulliam, @ethan_older, Hou, Campbell, @Tristan_enzymes, Awakawa, Yuan, @BradMoore_SIO in @Scripps_Ocean, Li nature.com/articles/s4155…
#Photobiocatalytic Enantioselective Benzylic C(sp3)–H Acylation by Yen-Chu Lu, Ronald Adukure, Satyajit Roy, Derek Chien, Matthew McGill, Sarthi Polara, Andrés Cisneros, Karl Scheidt, Rudi @FasanLab at @UTChemistry in @J_A_C_S pubs.acs.org/doi/10.1021/ja…
C–C Bond Cleavage in the Late-Stage #Biosynthesis of Huperzine Alkaloids Occurs via #Enzymatic Retro-Aza-Prins Reaction by Stefan E. Payer, Mario Prejanò, Philipp Kögl, Tamara Reiter, Eva-Maria Pferschy-Wenzig, Fahmi Himo, Wolfgang Kroutil in @J_A_C_S pubs.acs.org/doi/10.1021/ja…
Synergistic #Photoenzymatic Anti-Markovnikov Hydroarylation of Olefins via Heteroaryl Radical Intermediates by Prasun Mukherjee, @alassad_zayed, and Todd K. Hyster at @PrincetonChem in @J_A_C_S pubs.acs.org/doi/10.1021/ja…
NHC-Mediated Radical Acylation Catalyzed by Thiamine- and Flavin-Dependent #Enzymes by Shunsuke Kato, Shuto Fujisawa, Yuto Adachi, Mitsuhiro Bandai, Yutaro Mori, Seiji Mori, Tomokazu Shirai, and Takashi Hayashi in @J_A_C_S pubs.acs.org/doi/10.1021/ja…
Catalytic Enantioselective Smiles Rearrangement Enabled by the Directed Evolution of P450 Radical Aryl Migratases by @Wenzhen_Fu, Katherina Murcek, Jasper Chen, An Liu, Yunlong Zhao, Peng Liu (@pengliu_group), and Yang Yang (@yang2biocat) in @J_A_C_S pubs.acs.org/doi/10.1021/ja…
