Federico Gaiti
@fgaiti
Single-cell genomics, cancer biology & evolution | Scientist @PMcancercentre & Assistant Professor @UofT | @WeillCornell & @nygenome alumnus.
Excited to share our first lab paper, now published in @Dev_Cell! 🧠 How do glioblastoma (GBM) cells invade the brain, and what enables them to spread so effectively?
Identifying a high-risk type of T-ALL 🩸 A class of T-ALL patients with poor treatment outcomes can be pinpointed by their inflammatory gene score, offering new hope for personalized therapy. A study led by @UHN’s @DrStass, @s_jahangiri & @gowerfulScience science.org/doi/10.1126/sc…
Our study on T-ALL heterogeneity is out! We show ~1/3 of T-ALLs express inflammatory/stem signatures and are sensitive to venetoclax. Huge congrats to @gowerfulScience for leading the way, @s_jahangiri, and the entire team! science.org/doi/10.1126/sc…
Meet RESOLVE, our new method for mutational signature analysis just published in Nucleic Acids Research! Applied to 20,000 adult and pediatric cancers, it reveals key links to driver mutations and clinical outcomes. 🔗 doi.org/10.1093/nar/gk… #CancerGenomics #MutationalSignatures
Online now: Neurodevelopmental hijacking of oligodendrocyte lineage programs drives glioblastoma infiltration dlvr.it/TKpZcB
New insights on brain tumour invasion Our study found that glioblastoma cells hijack normal brain development processes to infiltrate brain tissue, informing new ways to control cancer spread—a team effort by @fgaiti & @gelarehzadeh’s labs @UHN. @Dev_Cell: cell.com/developmental-…
Metformin could reduce people’s risk of certain age-associated blood cancers, but more work is needed to identify who is likely to benefit go.nature.com/4jgMK6G
Congratulations to Dr. Federico Gaiti on receiving the 2025 Terry Fox New Investigator Award! With $525,000 from TFRI, Dr. @fgaiti will lead a team at @PMResearch_UHN to explore how glioblastoma spreads and returns after treatment. 🧵 Learn more 🔗 tfri.ca/our-research/r…
Congratulations to @PMResearch_UHN's Dr.@fgaiti who receives the @tfri_research New Investigator Award, supporting the next generation of #cancer researchers. 🙌
Congratulations to our scientist @fgaiti who received Terry Fox New Investigator Award from @tfri_research. tfri.ca/updates/news/n…
Congratulations to our scientist @fgaiti who received Terry Fox New Investigator Award from @tfri_research. tfri.ca/updates/news/n…
🚨Exciting news! TFRI has named five early-career scientists as the 2025 Terry Fox New Investigator awardees. With $2.6M in funding, they will advance critical research in melanoma, lung, brain, blood and pediatric cancers. Congratulations to the awardees! tfri.ca/updates/news/n…
Grateful to @tfri_research for supporting our work and vision! Huge thanks to my mentors—Drs. John Dick, @garybader1, @BrainSurgn1989—and to all colleagues and collaborators for their support. Excited to keep pushing #braincancer research forward! @PMResearch_UHN @pmcancercentre
🚨Exciting news! TFRI has named five early-career scientists as the 2025 Terry Fox New Investigator awardees. With $2.6M in funding, they will advance critical research in melanoma, lung, brain, blood and pediatric cancers. Congratulations to the awardees! tfri.ca/updates/news/n…
Read our latest #research on glioblastoma origins and growth, injury-reprogramming to neural crest-like identity, led by Akram Hamed from my lab, with @lincolndstein,@MarioniLab,@BenSimons_Lab, published with @SpringerNature in @nature, rdcu.be/d5n7I
Our study on T-ALL heterogeneity is out! We show ~1/3 of T-ALLs express inflammatory/stem signatures and are sensitive to venetoclax. Huge congrats to @gowerfulScience for leading the way, @s_jahangiri, and the entire team! science.org/doi/10.1126/sc…