eriksahailab
@eriksahailab
we want to find out how life works because we're curious and because we'd like to improve the outlook for cancer patients
Proud to share our new @Nature study: We developed the 1st NNMT inhibitor that reprograms cancer-associated fibroblasts, boosting immune response & stopping tumor growth in ovarian cancer models, especially when paired with immunotherapy. @OvCa_UChicago nature.com/articles/s4158…
I love this work!
How to turn a layer of fibroblasts into a tulip 🌷? Check out our new pre-print on shape-programmable living surfaces. Led by @pauguillamat @IBECBarcelona biorxiv.org/content/10.110…
Excited to share our new study on how resistance to AKT inhibition is linked to lineage differences within breast cancer 👇🏽biorxiv.org/content/10.110… and also surprisingly/worryingly good AI generated podcast 🎧notebooklm.google.com/notebook/28ebc…
Many congratulations Will, richly deserved. Looking forward to following your progress.
Thrilled to announce I'm moving to the @CRUK_MI to lead the Cancer Origins group! If you're interested in how mutations and exposures drive tumourigenesis—come join the adventure. cruk.manchester.ac.uk/careers/
Synthetic biology could enable new types of programmable therapeutics. Our new preprint introduces synthetic protein circuits that selectively trigger cell death in Ras-mutant cancer cells, with interesting advantages compared to existing approaches. biorxiv.org/content/10.110…
Really neat study applying new ML methods to our @cultureofcells imaging data to predict the fate of lung cancer cells following EGFR inhibition. biorxiv.org/content/10.110… see also biorxiv.org/content/10.110…
Thought provoking new study from the Sixt and Hannezo groups - the texture of the environment impacts collective vs single cell cancer invasion biorxiv.org/content/10.110…
Excited to share details of this meeting and the exciting line up of speakers. Hope to see you there. Please re-post crick.ac.uk/whats-on/5th-c…
Delighted to have contributed to this interesting set of perspectives on bridging gaps between fundamental and clinical research cell.com/cancer-cell/fu…
New paper from the lab🎈. Introducing Micro Immune Response On-chip (MIRO), a device that replicates tumors and their microenvironment to better understand responses to immunotherapies (cyan=immune cells, red=cancer, green=CAFs). @IBECBarcelona
Nice summary of some key discoveries published over the last 12 months
1/2024 was a big year for metastasis research! Check out our top articles on metastasis research from this year below. The field is driving progress and promise for patients with metastatic cancer. Join MRS for monthly updates on all things metastasis: metastasis-research.org/for-researcher…
Several years in the making (and aging), @Xueqian_Zhuang 's study on aging is out today @Nature. She finds, surprisingly, that aging suppresses tumorigenesis and stemness in the lung by promoting a functional iron insufficiency in the alveolar epithelium. nature.com/articles/s4158…
Adapmet is an amazing consortium working on cancer and metastasis and offers PhD positions. If you want to perform a PhD in these topics (either in academia or industry), please apply for these positions through the website interface before January 9th. Please forward the post!
📢Very excited to share this paper with you! The oestrous cycle stage affects mammary tumour sensitivity to chemotherapy published @Nature . Congratulations to Laura, @ColindaScheele and all the authors for this amazing story. nature.com/articles/s4158…
Couldn't agree more - what a great meeting and group of people.
Thank you for having me @evomet_itn, what a great group of peeps you are, especially the students 🤩🤩! Enjoyed it very much, gracias @RogerGom1 @SVanharanta @ClareIsacke and all :)
Excited to co-organize the virtual @EACRnews @Boehringer Conference: Drugging & Regulating the MAP Kinase Pathway! Submit an abstract or join us. Please RT and share with others. Details & registration: eacr.org/conference/boe…
Love this photo, perhaps the most rewarding part of my job is nurturing talent and seeing it flourish.
Also great to catch up with colleague @ActonLab and remember all days from @eriksahailab.
Great post-doc opportunity👇🏽
💥Exciting @ERC_Research funded postdoc opportunities in my lab at @CRUK_MI to study nutrient-host-microbiome interactions in cancer immunity in mice and humans. #CancerImmunology #MucosalImmunology #Microbiome ⏰Deadline: 1 December 2024 Apply 👇 cruk.manchester.ac.uk/recruitment/ca… ⏩RT
Thrilled to share our paper now out @Nature delineating #plasticity during #CRC #metastasis, a fantastic collaboration led by @andrewrmoorman @elliebenitez11, and @f_cambuli from the @KarunaGaneshLab and @dana_per lab! nature.com/articles/s4158… rdcu.be/dYAVK. A 🧵
Today we report in @NatureGenet the genetic landscape of cancer drug resistance mechanisms from CRISPR base editing screens nature.com/articles/s4158…