David Tang
@dtang2000
bioinformatics phd student at harvard interested in statistical genetics and genomics
super excited to share our new paper on polygenic epistasis! we introduce a new model and show how structured statistical epistasis can help us study complex trait biology. huge thanks to my friend and lab-mate @studyjeromics, and my mentor @andywdahl! biorxiv.org/content/10.110…
Very excited to share our preprint demonstrating that common genetic variants contribute to variable expressivity in rare telomere biology disorders! Highlights below 1/ medrxiv.org/content/10.110…
Our new work uses GxDrug interaction to model genetic effects on drug response in cross sectional data. Includes a new method for GxE TWAS. There are important caveats, but we hope this is a step toward more precise treatments
New preprint. In this paper we quantify heritability of drug response and identify involved genes by applying gene-environment interaction methods to biobank data. medrxiv.org/cgi/content/sh… 1/4
Our language decoding paper (@AmandaLeBel3 @shaileeejain @alex_ander) is out! We found that it is possible to use functional MRI scans to predict the words that a user was hearing or imagining when the scans were collected nature.com/articles/s4159…