Jonathan Rogers

📢Our new British Association for Psychopharmacology guidelines on CATATONIA are now out!📢 💠22 experts 💠3 continents 💠>500 references Read the full #OpenAccess guideline here: doi.org/10.1177/026988…. @BAPsych #catatonia

The EU have reduced clozapine FBC monitoring to 3-monthly after a year. Hopefully the MHRA will follow suit. @Maudsley_pharm were the first to trial this, and the only ones to report on safety. A huge step forward for patients, and rational science. medscape.com/viewarticle/eu…

New study of over 120,000 #clozapine therapeutic drug monitoring samples finds #smokers may need lower #plasma levels than nonsmokers for treatment-resistant #schizophrenia. Adverse drug reactions appear earlier in nonsmokers, particularly in women. 🔗 journals.lww.com/psychopharmaco…

Do you ever think about the consequences of a brain that cannot forget? Should we be rethinking the movement disorder known as dystonia and helping people to forget? A brilliant new perspective by Mark Hallett in the journal Parkinsonism and Related Disorders highlights something…

It is now widely known and accepted that while smoking significantly increases one's chances of developing lung cancer, many people who have never smoked develop the disease. Similarly, some people who have smoked their entire lives never develop lung cancer. Unfortunately, this…

🕰️ What is Temporal Drift? Data that clinical prediction models face when implemented can differ from the data they were trained on, even in the same setting. This can be due to changing patients, treatments or practices The result? The model’s predictions start to go wrong.

Good to see solid negative findings in catatonia research. It gives you confidence that studies are being conducted well. In this study of critically ill patients from @JoEllenWilson's group, frailty was not associated with development of catatonia. doi.org/10.1016/j.jacl…

I think this is the most exciting thing to happen in depression for research for at least the last decade. Pramipexole works for TRD.

Important study & big step forward for treatment-resistant #depression. 48wk RCT, #pramipexole showed ~4-point QIDS-SR benefit over placebo. Less hype, but bigger effects than psychedelic trials, for a scalable option that’s available to clinicians now. thelancet.com/journals/lanps…

Did a podcast with @DavidPuder and his team, it was a blast! Check it out if you’re interested in pediatric catatonia or catatonia in autism! podcasts.apple.com/us/podcast/243…

Medicine and #psychiatry in this country changed significantly today. Let’s hope this shift doesn’t come at the cost of quality #palliative care, or lead to premature, unnecessary deaths among the vulnerable, poor, and mentally ill. Time for the Lords to earn its keep…

My letter in The Times today. Having capacity is key to #Assisted Dying bill. Capacity safety amendments were voted down. Capacity can be complex & difficult even with years' of experience.

The HoC votes to allow people to prematurely end their lives, against the advice of the country's experts on suicidality - the Royal College of Psychiatrists. So-called "progressive" MPs ignored the experts, pursuing fantasies of individual autonomy in hubristic utopianism 1/2

Very exciting biomarker

Here's a free access link until August 7. authors.elsevier.com/a/1lHuj9UUH05C…

I'm a bit late to look at this paper, but it provides amazing insights into PD depression.

I'm so grateful to Max Fink for his work on ECT and catatonia, which has changed the lives of thousands of people for the better. On a personal level, he took the time at the age of 101 to meet me and provide guidance and mentorship. It was a great joy and privilege.

New paper on EEG in catatonia from the indefatigable James Luccarelli: psychiatryonline.org/doi/full/10.11…. ✅144 patients with catatonia and EEG (by far the largest n) ✅Catatonia not associated with abnormal EEG ✅Delirium (often comorbid in this sample) was associated with abnormal EEG

This is great from @rcpsych. Wisdom really is guiding.

Important finding