Todd Maderis, ND

Dr. Todd Maderis (@dr_todd) began his career in environmental medicine and specializes in helping patients find the root causes of illness. He and Dr Dempsey cover a wide range of topics comparing best approaches to helping the most complex patients. ThePOTScast.org

A new study contributes to the growing body of scientific research linking environmental toxins to cognitive decline. A Trichothecene mycotoxin, T-2 Toxin, has been shown to impair spatial learning and memory in a new animal study. What is interesting is T2 accomplished this by…

I had the pleasure of being on the Mast Cell Matters podcast with @DrTaniaDempsey hosted by Standing Up to #POTS standinguptopots.org/potscast/todd-…

Researchers from Stanford University just published a study identifying oxidative stress as a central, shared biological feature in both Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) and Long COVID. • Significant metabolic abnormalities were found in both #MECFS…

A newly published study evaluated Ixodes pacificus ticks collected from Southern Oregon and found evidence of multiple pathogens, including those that can cause #Lymedisease and other tickborne infections. What the Study Looked At- Researchers collected adult and nymphal ticks…

A recently published review article by dysautonomia expert Svetlana Blitshteyn confirms what many clinicians and patients already know: dysautonomia is a common, disabling, and often overlooked contributor to #chronicillness What is Dysautonomia? #Dysautonomia is a dysfunction…

Understanding the reason symptoms become chronic, even after the trigger is gone, may be the key to healing. Dr. Robert Naviaux- Dr. Robert Naviaux, MD, PhD, is a mitochondrial medicine researcher and pioneer in #chronicillness science. He discovered the Cell Danger…

A large real-world study published in PLOS One compared two testing methods for Lyme disease: 🔬 Modified Two-Tier Testing (MTTT) 🧪 Standard Two-Tier Testing (STTT) The results? MTTT detected 67.6% more positive cases in adults than STTT. Key takeaways: • MTTT was nearly…

Most doctors still rely on a 1970s model, using only TSH and T4 levels to diagnose and treat #hypothyroidism. But this model overlooks a critical truth: it's not about lab values, it's about tissue-level T3 effect. Lyme-literate physician (who introduced the Lyme community to…

New research identifies a connection between #endometriosis and small intestine bacterial overgrowth (SIBO), conditions that often go undiagnosed for years. The Study The authors report this is the first case control study that found that 91.9% of women with endometriosis…

A recently published study found that socioeconomic status played a major role in who experienced the worst flood and #mold damage after #Hurricane Ida in New Orleans. • Residents living in ZIP codes with a higher Social Vulnerability Index (SVI) were 3x more likely to report…

A 16-year-old boy suffered a stroke caused by #Lymedisease, bringing awareness to a rare but serious complication of tick-borne illness. The Patient’s Story • 16-year-old boy with a history of autism and epilepsy • Developed right-sided weakness and gait instability • MRI…

A newly published case report describes a rare and life-threatening complication of #babesiosis—Takotsubo (stress-induced) #cardiomyopathy. A 74-year-old woman developed severe babesiosis following a tick bite. Initial #tickborneinfection testing was negative. Her condition…

A recent New York Times article warns: #ticks are spreading faster and farther than ever before. Warmer winters and longer warm seasons are fueling a surge in tick populations, and the diseases they carry. Ticks Are on the Move- ✅ Deer ticks (blacklegged ticks) now reach deep…

A newly published study in the European Journal of Pharmacology discovered how carnosine improves colonic hyperpermeability (#leakygut) by working on the central nervous system, not just the gut. The researchers set out to investigate whether carnosine can regulate intestinal…

A new study from Penn State Health offers real-world insight into the symptoms and treatments for patients with HαT, a common but underdiagnosed genetic variant that elevates tryptase levels and can lead to #mastcellactivation. HαT and Anaphylaxis- ✅ 27% of patients experienced…

A new case report highlights the first confirmed imported case of #Babesia microti infection in China. A 52-year-old woman developed high fever, hemolytic anemia, and splenic lesions just one week after returning from rural Wisconsin, a known endemic area for…

A new study shows that #immunedysregulation and metabolic changes can persist for months after SARS-CoV-2 infection, even in people who had mild illness. Persistent Immune Activation- Researchers found long-lasting elevation of pro-inflammatory cytokines in #LongCOVID patients,…

A new study highlights a strong link between hereditary alpha tryptasemia (HAT), a genetic mast cell activation disorder, and life-threatening allergic reactions to certain antibiotics and monoclonal antibody therapies. Researchers found that individuals with HαT are…