Declan Creamer
@declan_c9
Biochemist/Research Associate @TheAsheLab @MCF_UoM interested in post-transcriptional control of gene expression 🪰 & protein homeostasis during stress ♨️
Very grateful to @ImmaginaBiotech for funding my proposal and excited to start experiments using #RiboLace soon! 🙂 #mRNA #translatomics
The results are in! 🏆 Congrats to the winners of our 3rd Ribo-Omics Challenge!🎉Stefanie Kaiser, Declan Creamer, Lisa Müller & Elisa Nicolini — your projects will push translatomics forward! We can’t wait to see the impact! More details: zurl.co/71rLX #ribosome #mRNA
It’s that time of year! 🎅🏼 We are collecting donations again for the wonderful @EmmelinesNew throughout November. See our flyer below for details of required items and where to bring them 🎁 @MCF_UoM @FBMH_UoM
We have a post-doc position using proteomics to dissect the translation process. Get in touch if you are interested or just apply!! jobs.ac.uk/job/DKD911/res…
🚨 Exciting PhD opportunity with @stu_art_here, @cjsmithdr and myself! Join us to investigate novel acute treatments for ischaemic stroke in the @BIG_research at @OfficialUoM🧠 findaphd.com/phds/project/m… #PhD #PhDposition @GJBrainResearch @FBMH_UoM
BREAKING NEWS The Royal Swedish Academy of Sciences has decided to award the 2024 #NobelPrize in Chemistry with one half to David Baker “for computational protein design” and the other half jointly to Demis Hassabis and John M. Jumper “for protein structure prediction.”
A bit of advertising for our review. Please take a look - we definitely spent a lot of time on this and dipped our toes well outside our comfort zone! Orchestrated centers for the production of proteins or “translation factories” - WIREs RNA wires.onlinelibrary.wiley.com/doi/10.1002/wr…
Very excited to share my first author paper out now in Cell Reports! We demonstrate how heat-triggered protein condensation helps reshape PKA signalling during stress conditions. @CM_Grant @Markashe @SimonHu02406809 @astacus @MCF_UoM Check it out here:
Isoform-specific sequestration of protein kinase A fine-tunes intracellular signaling during heat stress dlvr.it/T89c7j
Come find us at the Central Library in Liverpool to learn more about dementia! We have games & activities for all ages from little ones to adults 🧠🎲 Here until 4.30 #publicengagement #dementia @ARUKscientist @ComorbidCath @AlzResearchUK
Now published in @PLOSGenetics! journals.plos.org/plosgenetics/a…
Check out our latest preprint on the protective role of sequestrase chaperones during oxidative stress
Very pleased to announce the Ashe lab has been awarded a gold LEAF certification. The Laboratory Efficiency Assessment Network (LEAF) aims to reduce waste and improve lab sustainability. Great work by the lab LEAF team particularly Catherine Sutcliffe who championed the cause🍃🏅
Check out our latest preprint on the protective role of sequestrase chaperones during oxidative stress
Sequestrase chaperones protect against oxidative stress-induced protein aggregation and [PSI+] prion formation biorxiv.org/cgi/content/sh… #bioRxiv
Hot off the presses...our coolest study ever...seriously! By comparing a thermophile, mesophile, and cryophile, we show conservation and ecological tuning of heat-triggered biomolecular condensation from the ecological to submolecular scales 🔥🔬❄️ (🧵) biorxiv.org/content/10.110…
If you’re interested in a tool to help with protein quantification via mass spec, check out the AlacatDesigner pubs.acs.org/doi/10.1021/ac…
Glad to finally see this work out that I contributed to during my time in the Bukau lab!
The cytoprotective sequestration activity of small heat shock proteins is evolutionarily conserved, say Aseem Shrivastava, Axel Mogk, Bernd Bukau @BukauLab @ZmbhH and colleagues. bit.ly/3BilSQa @declan_c9 #Biochemistry #ProteinHomeostasis
Working on slides to explain biocondensates -). My boy may just have the right thing!
#RecentlyPublished Welcome to read "Yeast Protein Kinase A Isoforms: A Means of Encoding Specificity in the Response to Diverse Stress Conditions?" by Declan R. Creamer, et al. The article 👉mdpi.com/2218-273X/12/7…
First first author paper being published isn’t a bad way to end the week! Check out our review about kinase signalling in the stress response below @CM_Grant @profshubbard @Markashe @MDPIOpenAccess mdpi.com/2218-273X/12/7…