De-Chen Lin
@dechen_lin
Assistant Professor, University of Southern California, @ostrowusc, @uscnorris, GI and oral cancer, gene regulation, epigenomics
Linghua is on fire! Her work is absolutely amazing! A true leader in the spatial world!
Thrilled to see our work led by @liuyunho published in @Cancer_Cell featured by Nature Custom Media @Nature nature.com/articles/d4247… Huge thanks to @IanLeGuillou for the thoughtful interview, beautifully written piece @aubreybloom @claytonboldt @MDAndersonNews for their support
what an incredible work! huge congrats!! @IamLinghua
Thrilled to share our latest study just out in @Nature 😄A major milestone in our collaboration with @Aiims1742 Led by brilliant @GuangshengPei @jiminmin_v @MDAndersonNews nature.com/articles/s4158…
Thrilled to share our latest study just out in @Nature 😄A major milestone in our collaboration with @Aiims1742 Led by brilliant @GuangshengPei @jiminmin_v @MDAndersonNews nature.com/articles/s4158…
Congrats Ryan!!
Excited to share our study led by fellow Lawrence Wu, focusing on the molecular characterization of early-onset esophagogastric cancer. We explore transcriptional profiles, immune microenvironment, and real-world survival outcomes. rdcu.be/ewEsO
Congrats @FadenLab Very important work!
A new liquid biopsy blood test could help detect cases of human papillomavirus (HPV)-associated head and neck cancers. The test has the potential to be significantly more accurate than current methods, including before symptoms develop, according to new Mass General Brigham…
Have been hovering around 20-25% for more than a year now...need some breakthrough 💪✍️
An amazing work from @IamLinghua Very impressive!!
1/ Out today in @Cancer_Cell our work on spatial subtypes and cellular neighborhoods of cancer-associated fibroblasts (CAFs)! Led by the brilliant @liuyunho with key contributions from @Aiims1742 @humam_kadara and many collaborators @MDAndersonNews cell.com/cancer-cell/fu…
Very well said!! Protect NIH is protect life!!
Did you know - the medicine that President Trump takes each day to lower his risk of having a heart attack is a direct result of NIH funding? Let me explain -
Basic science is inspired by curiosity, accountable to evidence, and subject to peer review. Politics should have no role.
Here is a growing list of #universities and #programs that have to reduce or pause graduate admission as a consequence of indirect cuts, and funding freeze. We are witnessing an entire generational loss of #science.
Lawyers for the government argued yesterday that the cap on NIH indirect costs would not cause “irreparable harm,”- Tell that to the grad students who would have been admitted at these places and the labs they would have joined! H/T @kyledcheney docs.google.com/spreadsheets/d…
NIH funding creates medicines, jobs, and economic growth
"More than 99% of new drug approvals (2010-2019) were funded by NIH. Why dismantle the engine that made the U.S. a world leader in innovation and drug development ? #DoNotDefundScience jamanetwork.com/journals/jama-…
The Trump administration's efforts to slash research funding have US graduate students, postdocs and other early-career scientists fearing for their careers. Some are considering changing jobs or leaving the country. Others say them might abandon research altogether.…
Join us for a free webinar presented by the AHNS Basic & Translational Science Service: "From the Bench to the Bedside: Using Preclinical Models to Advance Head & Neck Cancer Management" Register now! Wednesday, January 22, 2025 - 7 PM EST ow.ly/c2F550UIKqx
Happy to share our new perspective on patient-derived tumor organoids to model drug response in gastric cancer: cell.com/cell-reports-m…
I’m excited to share our new study of the mechanisms of action of the therapeutic target ONECUT2 in prostate cancer. The protein activates a surprisingly wide range of resistance mechanisms. But we can suppress it with a drug! @PCFnews @PCF_Science doi.org/10.1093/nar/gk…
Check out our new toolkit for cell type deconvolution from DNA methylation sequencing. Open-source and ready to use! Congrats to @UntIrene who worked tirelessly on this & thanks to @ChristaCaggiano and Noah Zaitlen who inspired us with the CelFiE approach. genomebiology.biomedcentral.com/articles/10.11…
New Cancer Cell publication! "Let it be: Preserving tumor-draining lymph nodes in the era of immuno-oncology" @UCSDMedSchool @UCSDCancer @rsaddawi sciencedirect.com/science/articl…
🚀Excited to share our latest preprint on the Methylation Screening Array (MSA) design to facilitate human EWAS discoveries. MSA leverages previous EWAS, bulk, single-cell WGBS data, and technologies for ultra-high throughput profiling. Checkout details: biorxiv.org/cgi/content/sh…