Colin Hoy
@colinwhoy
Motivation in Parkinson's disease via DBS and RL @UCSF w/ @littleneuro + #neuroethics w/ @WinstonChiong | neuro PhD @UCBerkeley | he/him @colinwhoy.bsky.social
Our study on reward and effort signals in PFC theta and basal ganglia beta is now out in @PNASNews! Big thanks to the team (esp @coradehemptinne and @littleneuro), reviewers, and patients. pnas.org/doi/10.1073/pn… Data: osf.io/jq6z4/ Code: github.com/hoycw/PRJ_OFC_…
My 1st postdoc preprint! iEEG dissociates reward/effort in PFC theta/BG beta during decisions + PFC stim boosts reward effect on choice. Huge thanks: @coradehemptinne & @littleneuro for heavy lifting early on & Sarah Wang, @OxfordPERL, @brain_apps, @MasudHusain, Philip Starr!🧵⤵️
1/18: Well, after 23 years as faculty at Harvard and almost 15 years of amazing collaborations, collegiality and growth at McLean Hospital, today I officially start at @UCIrvine, where I will be the founding director of a new depression
do I know any neuroscientists on this platform? we're hiring a neuroscientist come help us build a biohybrid BCI please share if you know neuroscientists
Why theta? Always wondered this and presumably there are multiple answers, but this is an intriguing one
🎉Finally published @PLOSCompBiol ! Why do neurons use low-frequency oscillations for encoding? Why not use higher frequencies for better sampling resolution? We identify a speed-precision trade-off driven by noise, showing that theta (3–8 Hz) maximizes bits/s! Check it out 👇
The @ParkinsonsUK Tech Guide has recently been launched as a place to discover devices and apps aimed at people with Parkinson’s 📱 Explore the Tech Guide yourself or share it with patients who want to learn how technology can help manage the condition: bit.ly/3OCXVZK
🚨Our latest pre-print is now available on @medrxivpreprint!🚨 medrxiv.org/content/10.110… We studied 1,402 patients to comprehensively assess the diagnostic + prognostic value of alpha-synuclein seed amplification assay in Parkinson’s disease. See below for our main findings (1/14)
New paper out in @NeuronCellPress: A general theory of sequential working memory in prefrontal cortex and RNN/SSMs with their exact neural mechanism. Plus unifying this new mechanism with the alternate mechanism of hippocampal cognitive maps! (1/9) cell.com/neuron/fulltex…
I'm excited to share our #NeurIPS2024 paper with @jsoldadomagrane @SmithLabNeuro @YuLikeNeuro! We develop a new brain stimulation framework (MiSO) to drive neural population activity toward specified states. Paper: openreview.net/pdf?id=Gb0mXhn… Poster Session 4 East, Dec 12 16:30 [1/n]
Hi anyone that's still here, I'm moving away from this account. I'll be active on @colinwhoy.bsky.social so hope to see you (and less bots/junk) there!
Funded PhD (UK students only). Interested in a PhD working in @MSNlab, co-supervised by @froemero1? Topic is flexible around themes of motivation and decision-making, using techniques such as computational modelling, brain imaging, or brain stimulation. tinyurl.com/543ucffd
🎙️ Just 2 days to go! Join us for an insightful talk from @ArynGittis and @drpouratian. Don’t miss the chance to dive deep into the latest and greatest in optogenetics and pallidal burst stimulation. 📅 October 31st 🕒 12 PM ET/5 PM CET 🖥️ Register now 👉 partners.zoom.us/webinar/regist…
Thrilled to share this study on LFP physiomarkers of anxiety in PD. Humbled and honored to have worked on this transatlantic triple-cohort project with the most incredible team @littleneuro @LuciaRicciard10 @colinwhoy @franci_morgante
Theta power in basal ganglia indexes #anxiety in people with #Parkinson. Great collaborative work led by @LuciaRicciard10 and @littleneuro academic.oup.com/brain/article/… @StGeorgesUni @UCSF
Our latest paper is out! We looked at the roles and interplay of reinforcement and error feedback on exploration during reaching and gait for neurotypical individuals and those with Parkinson's disease. journals.plos.org/ploscompbiol/a…
Have you ever had a song stuck in your head? Then you might be interested in our new #musicscience work just published in @PLOSBiology doi.org/10.1371/journa… We used decoding to investigate how the brain represents perceived and imagined musical sounds. TL;DR below 1/
Did you ever have a melody stuck in your head? Then you may be interested in our new #musicscience work. We used decoding techniques to investigate how the brain represents held and manipulated musical thoughts: doi.org/10.1101/2023.0… Check it out! Feedback is welcome.
🚨🥁Preprint alert: #DBS Programming is currently a tedious trial and error process that involves testing many settings – each time asking the patient to perform motor tasks to see how things improve. Could we use DBS-#evokedpotentials to guide programming?doi.org/10.1101/2024.1…
Want to study or teach some #neuroscience, its #philosophy, or #neurophilosophy, but feel unprepared? Use our free Beginner's Guide to @NeuralMech-anisms! TWO animated shorts about free will and mereological fallacies + SIX sets of mini-presentations: youtube.com/watch?v=1kLvZ6…
✨Rethinking reinforcement learning: the interoceptive origins of reward doi.org/10.31234/osf.i… An honour and *absolute delight* bouncing ideas with these brilliant women: @debyeeneuro @danamsmall @rikepetzschner What are primary reward signals and where do they come from?
This is wild... decoding associated memories based on auditory cues during sleep... FROM EEG! 🤯
here is a little demo for real-time sleep staging, and memory content decoding during sleep
A few postdocs asked me to read over their job applications. Here’s a few bits of advice: 🧵 /10 1. If any advice doesn’t ring true for you, discard it (including this!) 2. People on the search committee are keen to welcome a colleague, they aren’t looking to take you down
Check out our new @NeuroCellPress paper led by @NitaFarahany & @PatrickMageez "Beyond Neural Data: Cognitive Biometrics and Mental Privacy". It highlights how #AI-powered devices (e.g., wearables, #BCIs) process a new class of data called 'cognitive biometrics', raising mental…