Chuck Lynch

Happy to share that our work applying precision mapping to individuals with depression sampled longitudinally over an extended period has been published this week in @nature. Brief recap of the main findings and their potential implications below. nature.com/articles/s4158…

Our preprint detailing our novel approach to identifying personalized neuromodulation targets to treat severe, refractory OCD using brain mapping is now out on MedRxiv. Here, we describe our first SEEG-guided DBS case for OCD at UCSF: medrxiv.org/cgi/content/sh…

1/11 Excited to share our @Naturestudy led by @Leon_Oo1 @csabaorban @ZShaoshi doi.org/10.1038/s41586… It is well-known that AI performance scales with logarithm of sample size (Kaplan, McCandlish 2020), but in many domains, sample size can be # participants or # measurements...

Pain in the brain! check out the thread: bsky.app/profile/drdami… on the new preprint: osf.io/preprints/psya…

Our brain-to-voice synthesis brain-computer interface paper was published in @Nature today! This neuroprosthesis synthesized the voice of a man with ALS instantaneously, enabling him to ‘speak’ flexibly and modulate the prosody of his BCI-voice. 1/7 Paper: rdcu.be/eqH3C

Excited to announce that our paper (led by @hyejinjad & Derek Smith) is out in Nature Human Behavior: go.illinois.edu/Lee2025_NHB We use 36 days of testing in 4 inhibitory control tasks to examine the precision of inhibitory control measures in *individuals* and how they vary 🧵👇

First tweet on an exciting new manuscript online @NatureNeuro - in collab with @LucinaUddin and Catie Chang. We take a fresh look at the physiological dynamics associated with the global signal 🧠... #neuroscience #neuroimaging #fMRI Read here: rdcu.be/ek01F

New preprint by @afni_pt on how you should be presenting your imaging results! arxiv.org/abs/2504.07824#

New paper in Imaging Neuroscience by Anita S. Jwa, Martin Norgaard, and Russell A. Poldrack: Can I have your data? Recommendations and practical tips for sharing neuroimaging data upon a direct personal request doi.org/10.1162/imag_a…

1/9: Delighted to announce that our faculty cluster hire for the newly established Noel Drury, M.D. Institute for Translational Depression Discoveries at UC Irvine is now live. The submission deadline is April 9, 2025.

Averaging brain responses is not really a great idea... #neuroscience doi.org/10.1038/s41467…

Honored to share that I will be speaking at @TedTalks #TED2025 "Humanity Reimagined" conference in Vancouver, April 7-11. Looking forward to what will surely be an inspiring week. More info here ⬇️ conferences.ted.com/ted2025/speake…

Finding of considerable “mood instability” between major episodes of #depression and #mania / hypomania in #bipolar disorder could lead to care approaches that improve lives. . Read the full article: ow.ly/liFa50UZv4P . @UMich @umichmedicine

New research investigates deep brain stimulation of the ALIC treatment for severe OCD. The findings suggest default mode network suppression mediates clinical benefits by improving cognitive flexibility and reducing compulsive behaviors. onlinelibrary.wiley.com/doi/10.1002/hb…

Trends in Cognitive Sciences Using precision approaches to improve brain-behavior prediction cell.com/trends/cogniti…

🌟 We did it again :-) Proud to announce our publication in Brain @Brain1878! Our study sheds light on the Plis de Passage—known anatomical structures but never thoroughly examined thoroughly at the subcortical level. By integrating anatomical, functional, and…

The architecture of the human default mode network explored through cytoarchitecture, wiring and signal flow. nature.com/articles/s4159…

Nature Neuroscience The architecture of the human default mode network explored through cytoarchitecture, wiring and signal flow nature.com/articles/s4159…

Drs. @ndosenbach, Marcus Raichle & @gordonneuro explore how the brain's action- and default-mode networks balance each other like yin & yang, suggesting an integrated understanding of how it processes different info types in @NatRevNeurosci. #MIRresearch nature.com/articles/s4158…

The brain’s action-mode network and default-mode network counterbalance each other as yin and yang. 🧵1/10

Nature Reviews Neuroscience The brain’s action-mode network nature.com/articles/s4158…