Christian Mayer (@[email protected])
@chr_mayer
Group Leader at MPI-BI, studying neuronal dev and differentiation. Also on Mastodon (@[email protected] ) where I value open, community-driven science.
Now out in #NatureNeuroscience: new paper from our lab — "Temporal control of progenitor competence shapes maturation in GABAergic neuron development in mice." Congrats to first authors Ann Bright, Yana Kotlyarenko, Florian Neuhaus! nature.com/articles/s4159…
Hiring alert 📢 my lab has TWO openings for a postdoc in computational biology! Please apply if you're interested to work with large in situ RNA-seq datasets and amazed by developing biological neural networks (mouse brains): ki.varbi.com/en/what:job/jo… ki.varbi.com/en/what:job/jo…
My lab is looking for a research assistant to work on barcoded viral tracing in the developing mouse brain: ki.varbi.com/what:job/jobID… Please apply if you’re interested to explore molecular mechanisms of neural circuit assembly in vivo!
Using in vivo CRISPR perturbation, lineage tracing, and ChIP–sequencing provides insight into how inhibitory neuron identity is determined in the developing germinal zone @edvoretskova • @chr_mayer • @MPIforBI nature.com/articles/s4159…
Attended the Neurogenomics Conference @humantechnopole in Milan earlier this week. Great venue and an inspiring environment. Thanks to the organisers for putting together a strong and engaging meeting. #NeuroGen25
Interested in single cell genomics but need help getting started? Check out the full agenda for our Single Cell Genomics Day on Friday 4/25. All talks will be live-streamed (no registration required) at satijalab.org/scgd25
The Single-cell Analytics Innovation Lab @MSKCancerCenter is expanding and looking for Junior Research Technician! Join our team based in NYC to work on cutting-edge single-cell & spatial genomics methods in collaboration with leading research labs. sail.mskcc.org
🚨🎓 New application round: Join us in researching the multiple facets of biological intelligence and become a PhD student at our fully funded graduate school IMPRS-BI in the Munich area! 🔔 Application period: October 1 to November 10 🌐 Apply here: imprs-bi.mpg.de
📅 Save-the-date! We are excited to welcome @chr_mayer to @mpi_psychiatry as our next MPLS speaker on 11. July (Thu). His talk will shed light on fundamental neuronal mechanisms 🧠 and the pathways 🧬 contributing to #neurodevelopmental disorders. This talk is open to everyone!
Our latest from @briscoejames lab: How temporal & spatial pattering cues are integrated in the vertebrate neural tube to organise cell type generation during development. biorxiv.org/content/10.110…
Outstanding PhD work by our super-talented Lucia Del Valle, with the help of superb collaborators at @NeuroAlc @MPIforBI @LMU_Muenchen @CsicLifehub @CSIC @SENC_ science.org/doi/10.1126/sc…
Happy to see our new story published. 3 types of cortical Radial Glia Cells revealed: alpha, beta and gamma, with different amplificative behavior and involved in different cell lineages, that run together and in parallel in different germinal layers. Ferret is a superb model (1)
Looking forward to diving into the final version of this work. Excited that others also find differential binding as a chromatin strategy for alternative cell fate choice.
Enhancers that drive projection neuron-specific gene expression are accessible in all parts of the GE (ATAC-seq Rhodes et al). Yet, their activity is restricted to the LGE. Thus, "differential TF binding" rather than "differential accessibility" induces projection neuron fate 6/7
A team led by Christian Mayer discovered that a protein called MEIS2 plays a crucial role in the formation of GABAergic projection neurons. These neurons enable various brain functions, and a failure of MEIS2 to control their development may contribute to neurodevelopmental…