Tri-I CBM

Hi all, I am currently on the academic job market. I am a postdoctoral researcher in Dr. Christina Leslie's lab at the Computational and Systems Biology Program at Memorial Sloan Kettering Cancer Center. My research focuses on deciphering causal and dynamic gene regulation…

💥💥💥New preprint 💥💥💥on the EuPRI resource. Where we reconstruct the motifs for 34,736 RBPs and study their function and evolution. Joint work with @ProfTimHughes (Toronto), Matt Weirauch, @LXandR_, Deb Ray, Kaitlin Laverty and many more. More details to come

Happy to announce that PERT is now published in @NatureComms ! With PERT, we explore replication timing variability (Fig 3-4), chrXi reactivation (Fig 5), and how S-phase fractions struggle to approximate clone fitness (Fig 6). nature.com/articles/s4146… 1/n

Excited to publish my book chapter with @mason_lab @Springernomics and edited by @sonivijay07 and Dr. Akhade on Role and Relation of Microbiome to address AMR.

AutoFocus, a project YEARS in the making, is finally out in @CommsBio! When clustering multi-omic data, systemic correlation bias focuses on intra-omic clusters and excludes multi-omic interactions - so we designed an algorithm to help change the focus: nature.com/articles/s4200…

Our paper is out! Automatic ploidy prediction and quality assessment of human blastocysts using time-lapse imaging .. congratulations to my star PhD student and first author @rajsuraj99 @cbm_student @WeillCornellGS @WCMEnglanderIPM @WeillCornell nature.com/articles/s4146…

We are humbled to have our lab's work featured this week on the cover of @Nature (below), with many, many people to thank. First, the stellar crew of @inspiration4x, @rookisaacman, @ArceneauxHayley, @ChrisSembroski, @DrSianProctor, who donated time, blood, fluids, and sweat for…

During National Postdoc Appreciation Week, we post social cards and profiles to celebrate our remarkable #MSKPostdocs (@MSKPDA). A week is not enough, so we dedicate ALL of September to our outstanding scientists! Stay tuned to learn more about them. @MSKCancerCenter #NPAW2024🎉

We are at #ISMB24 in Montreal ! Come listen to @cbm_student Marjorie Roskes talk at #HitSeq on Sun at 5:20 pm, visit Weiling's poster A-133. Or shoot me a message if you would like to chat about opportunities in the lab.

Paper out!📢 @AnupriyaSingha9 and #HannahStyers from the lab find acute resistance to targeting KRAS in pancreas cancer is surprisingly driven by a classical epithelial state. Co-targeting classical cells and KRAS augments response - clinically important! aacrjournals.org/cancerdiscover…

Metient reconstructs the migration histories of metastatic cancers by scoring a Pareto front of parsimonious histories. It can be auto-calibrated to different cohorts. Superstar PhD student @divyakoyy will present at #ISMB2024 in MLCSB Check it out: biorxiv.org/content/10.110…

Thrilled to announce that my PhD thesis work has been published in Nature Genetics! 🎉 Huge thanks to my advisors, @SohrabShah and @EdReznik, for their guidance and support throughout the years!

✨New paper alert @CD_AACR✨ - GDD-ENS distinguishes 38 cancer types (>96% of patients) w/ high accuracy using routinely collected DNA sequencing data #MSKIMPACT and generalizes well to other gene panels w/o retraining - CNAs (arm/gene level) are key features for classification

So proud to see the defense of Mar (Mohith) who worked in our lab on new algorithms for detecting and phasing 8-oxo-guanosine and other base modifications from @nanopore data from Earth and in space @cbm_student #defense @WeillCornell

Congratulations to our brilliant @dfhoyosg @cbm_student @CompOncMSK @MSKCancerCenter on being named a Hertz Fellowship Finalist!

1/ Not every #oncogene acts like an oncogene – context is key. Here, with the Varmus Lab @WCM @WCM_MeyerCancer, we demonstrate an ‘oncogene’ in the wrong cell type doesn’t act like an oncogene anymore. science.org/doi/epdf/10.11…

Our newest journal article is now out! Shout out to incredible Ph.D. @cbm_student from the lab, Dr. @meleshko_da, and wonderful @WeillCornell collaborator @hagentilgner: doi.org/10.1093/bioinf…

🎙️ Alon Millet's talk is on YouTube! "An exhausted-like #microglial population accumulates in aged and #APOE4 genotype Alzheimer’s brains" (Ref: Immunity 2023) @AlonMillet @Jhledo @SohailTavazoie @RockefellerUniv @cbm_student youtu.be/IiQK_NrjN7o #Openscience