CannaLab
@canna_lab
Auto- & Hyper-inflammation | MAS HLH | IL-18 | Down wit OPD | ❤️er of puns (see logo) | 🚲 evangelist | opinions my own
"Modeling the HLH immune synapse uncovers critical roles for IS termination, cytokine intensity, and target cell death" #HLH travels under many names (#MAS, #CRS, ...), all united by T-cell hyperactivation. doi.org/10.1182/blood.…
Welcome to Philly, where it's always sunny. Additionally, I'm dropping my worst puns over where the grass is greener on the posting site where the sky is bluer.
On my way to @ClinImmSoc annual meeting! @Info4PI
Why are we doing this on X? Every view, every post is $ in DOGE's pocket. The only thing keeping us here is market share. I have no $ in @bluesky, but I'm @cannalab.bsky.social
T cells do the heavy lifting when it comes to the anti-tumor action of checkpoint immunotherapy. But do antibodies play a role too? That’s the question @yile_dai looked to answer in his thesis work, out today in @Nature! 🧵below nature.com/articles/s4158…
"Multi-Disciplinary Approach to Managing #HLH" Register at us02web.zoom.us/webinar/regist…
Join us for a webinar: Multi-Disciplinary Approach to Managing HLH with Drs. Jessica Manson & Rachel Tattersall, who have led a UK-wide effort to bring excellent HLH care to their institutions and the broader NHS and to track the outcomes of their interventions. @canna_lab
thx @LabWaggoner, beat us to it!
Preprint: Multimodal induction of fulminant HLH by IL-18 includes virus-specific NK immunodeficiency @canna_lab @varghese_jemy biorxiv.org/content/10.110…
Honored by shout-out from the legendary Dr. De Benedetti at #EULAR25 Check out @AFKamenetskii 's paper. @BloodPortfolio doi.org/10.1182/blood.…
Fun writing "Insights from the 2024 ACR/PRES Peds Basic/Translational YIR" with the talented Dr. Jessica Turnier @umichmedicine. Thx for invite @ChristophKessel and PROJ. 1st time citing @DGlaucomflecken ... so far. link.springer.com/article/10.118…
Drs. Manson & Tattersall have led a UK-wide effort to bring consistent, excellent #HLH care to their institutions & the broader @NHSuk ... & tracking their outcomes. Please register: us02web.zoom.us/webinar/regist…
@HistiocyteSoc #HLH Webinar "Multi-disciplinary Approach to Managing HLH" Headlined by @JessicaJManson & @R_tattersall (@ucl) who've really brought HLH excellences to @NHSuk July 24th, 11AM NY/8AM SF/4PM UK/5PM CET Details and link are forthcoming
The gut-wrenching irony of so many libs voicing their outrage ... by donating content to X.
Power-plays aside, this (science.org/content/articl…) is short-sighted The backlash is building. It will insist on protecting NIH from future reckless sabotage. It will make NIH even more resistant to reform.
Just to be clear: this presentation represents fanfiction of characters created by, and belonging to, @sjiafoundation.
Cast of Characters in SJIA / Still's
I heard some rowdy #IL18eenagers are planning to liven up tomorrow's @sjiafoundation #RareDiseaseDay event. @rashmi @lupapaleopeixo1
Coming up tomorrow. Be there!
Great turnout in Philly for #StandUpForScience2025 #NIH
📣New paper alert from the lab! Lab alumni Isabel, @n_toothacre, @claudia_lovell from @CAMBUpenn together with @PennEpiInst faculty @ericjoycelab @creminsLab investigate 3D ultrastructure of the inactive X in B cells. cell.com/cell-reports/f…
For SJIA/Still’s patients, rare disease day event organized by Systemic JIA Foundation.
SJIA/Still's Rare Disease Day ahead! Social Hour for patients and caregivers on March 8, 2025, 10:00 AM ET. Register on link below. #cureSJIA #rarediseaseday 🔗 systemicjia.org/rare
calculations s/p more news @NIH LOTR Th-What can [we] do against such reckless hate? Ar-Ride out with me. Ride out and meet them. +HG Wells "Every time I see an adult on a bicycle, I no longer despair for the future of the human race." = @BromptonBicycle n+1 to rule them all
![canna_lab's tweet image. calculations s/p more news @NIH
LOTR
Th-What can [we] do against such reckless hate?
Ar-Ride out with me. Ride out and meet them.
+HG Wells
"Every time I see an adult on a bicycle, I no longer despair for the future of the human race."
= @BromptonBicycle
n+1 to rule them all](https://pbs.twimg.com/media/GkAM9y4WQAASe0Y.jpg)
What a scientific, clinical, educational, and social privilege to host @cecipolih! See you soon.
I had the most wonderful time and learned so much! So grateful of the whole Rheum/Immuno/DIRT team @ChildrensPhila @canna_lab @katesullimmuno I will miss CHOP !