Bushman Lab
@bushmanlab
Microbiology lab at UPenn, focusing on host microbe interactions in heath and disease. Tweets are in personal capacity. RTs are not endorsements.
Political attacks on writers and thinkers are nothing new. Tacitus, writing about the repressions of Tiberius, commented on “…the stupidity of people who believe that todays authority can destroy tomorrow’s memories. On the contrary, repressions of genius increase its prestige.”

The human immune system is wondrous Vaccines harness it and make it even better
Check out new art at The SPACE gallery, featuring photographs of layered weathering graffiti. All proceeds to the artist are donated to Philabundance, to address food insecurity in our area. thespacephiladelphia.com/online-store-f…

open.substack.com/pub/pauloffit/… RFK Jr. has just put healthy young children at risk. He should step down at head of HHS. Enough.
youtube.com/watch?v=i0q_Oj… A brilliant, thoughtful takedown of RFK Jr. by Dr. Mike Varshavski.
Congrats to Lydia Mendoza and the team on their latest publication: detailed characterization of immune responses against recent influenza strains at the Hospital at the University of Pennsylvania. PMID: 40452165.

In case you were wondering why research is important: check out the song from Mags McCarthy and Bruce Levine on saving lives with novel cancer therapy: youtube.com/watch?v=dkOrbj…
No it doesn't "make sense" Polio vaccine doesn't cause cancer It prevents polio More insane anti vaccine ranting from HHS Secretary RFK Jr
Contrats to Saira, Kushol and the team on an important publication on HIV integrase structure and inhbitor resistance. Escape from allosteric inhibitors is associated with notable conformational changes. PMID: 40409709

Excited about the seminar from Melissa Smith at noon today. Long read sequencing applied to problems in microbiology and immunology. Please join us!

One boy was vaccinated The other was not Guess which one is which?
Thanks so much to Bruce Walker for the moving talk on HIV immunology and mitigating AIDS in Africa. It is heartbreaking that federal cuts to PEPFAR over the next four years are projected to result in 4 million additional deaths and 6 million additional infections (UNAIDS).

Dr. Griffin with Vincent Racaniello deplore the US’s withdrawal from the global health community for pandemic preparedness, RFK’s autism registry, yellow fever outbreak in Colombia, world immunization week, & more. 📺 bit.ly/3EB76Zg
We are now approaching 900 official cases of measles This is already the 2nd worst measles outbreak of the 21st century — and we are only in April 94 hospitalized (mostly kids) 3 dead Our leaders need to be clear and unequivocal about how to end this: Vaccines
The Felon-in-Chief really, really, REALLY hates this Fox graphic. So whatever you do, don’t share it anywhere. 😈
Since 1945, American Universities have been envied worldwide for their Government-funded research. Hard to justify via corporate R&D, frontier science is vital to our long-term health, wealth, & security. To withhold such funding is to amputate the engines that Make America Great
Microbiology Seminar 🔬 Mark your calendars! Please join us for the annual -Neal Nathanson Lecture- Wednesday 4/30/25 12-1PM CRB Austrian Auditorium Bruce Walker, MD "HIV as a model for immune control and immune failure: Insights from Africa" ragoninstitute.org/bruce-d-walker/
Congrats to Marie Seleme, Aradhana Kasimsetty and the team on their report of effective methods for increasing expression from AAV vectors by blocking SUMOylation. Effective boosting by treatment with an inhibitor presently under investigation in humans! (PMID: 40263936)

RFK Jr. says it’s time to give infectious diseases a break and focus solely on chronic diseases, but will they give us a break? This video is based on Dr. Offit’s substack post, “Giving Infectious Diseases a Break.” 📺 bit.ly/4lF9PBn