Brain and Sleep Research Laboratory

@bsrlaboratory

The Brain and Sleep Research Laboratory is a joint effort of Luisa de Vivo and Michele Bellesi to investigate the neurobiology of sleep and wakefulness

Camerino, Italy

Joined January 2019

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Brain and Sleep Research Laboratory@bsrlaboratory · Jul 3

Cholinergic basal forebrain neurons regulate vascular dynamics and cerebrospinal fluid flux nature.com/articles/s4146…

bsrlaboratory's tweet card. Nature Communications - The authors find cholinergic neurons regulate glymphatic waste clearance via neurovascular mechanisms, with their loss impairing this process. This finding suggests targets...

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Brain and Sleep Research Laboratory@bsrlaboratory · Jul 17

Mitochondrial origins of the pressure to sleep nature.com/articles/s4158…

bsrlaboratory's tweet card. Nature - Research on Drosophila neurons shows links between the need to sleep and aerobic metabolism, indicating that the pressure to sleep may have a mitochondrial origin.

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Julie Seibt@julie_seibt · Jul 11

To all rodent sleep researchers 🚨! Tired of non reproducibility in sleep scoring? The @ESRS_Sleep launches a call to develop a manual for the recording and analysis of sleep in laboratory rodents. Apply here (shorturl.at/ibseX) if you are interested!!

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Consciousness - tlab@conscious_tlab · Jul 4

㊗️ our paper was finally accepted by Nature Communications! Data & paper are already accessible from here: DREAM: A Dream EEG and Mentation database osf.io/preprints/psya… Thanks all coauthors for contributing the data! It was a really long journey to arrive here...

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Brain and Sleep Research Laboratory@bsrlaboratory · Jun 25

Neuroendocrine circuit for sleep-dependent growth hormone release: Cell cell.com/cell/fulltext/…

bsrlaboratory's tweet card. The increase in growth hormone release during sleep is driven by sleep-wake-dependent activity of stimulatory GHRH neurons and inhibitory SST neurons in the hypothalamus. The released growth hormone...

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Brain and Sleep Research Laboratory@bsrlaboratory · Jun 18

A time window for memory consolidation during NREM sleep revealed by cAMP oscillation: Neuron cell.com/neuron/fulltex…

bsrlaboratory's tweet card. Sleep is crucial for memory formation. Deng et al. find that cAMP levels in mice oscillate with a 1-min cycle during slow-wave sleep, and hippocampal activity at the peak of these oscillations is...

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Brain and Sleep Research Laboratory@bsrlaboratory · Jun 6

Increased CSF drainage by non-invasive manipulation of cervical lymphatics nature.com/articles/s4158…

bsrlaboratory's tweet card. Nature - The outflow pathway of cerebrospinal fluid into lymph nodes in the neck and how non-invasive mechanical stimulation can enhance drainage and restore impaired outflow in aged mice are...

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Yuval Nir 💔@LabNir · May 16

Astrocytes.. we haven't been paying enough attention: science.org/doi/epdf/10.11…

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Brain and Sleep Research Laboratory@bsrlaboratory · May 6

The great brain clearance and dementia debate nature.com/articles/d4158…

bsrlaboratory's tweet card. Nature - An established theory for how good sleep reduces a person’s risk of neurodegenerative disease has been called into question. The ensuing argument could have enormous consequences for the...

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Brain and Sleep Research Laboratory@bsrlaboratory · May 2

Global coordination of brain activity by the breathing cycle nature.com/articles/s4158…

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Martin Picard@MitoPsychoBio · Apr 28

How much energy does it cost to fuel cognition and everything else the brain does? Fueling the brain costs 20-25% of the whole body's energy budget, even if the brain is only around 2% of body weight Thinking hard doesn't change energy demand much cell.com/trends/cogniti…

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Brain and Sleep Research Laboratory@bsrlaboratory · Apr 29

Parallel processing of past and future memories through reactivation and synaptic plasticity mechanisms during sleep nature.com/articles/s4146…

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Leonardo Dalla Porta@ldallap1 · Apr 24

Spatiotemporal dynamics of cortical slow waves in the human cortex (in vitro) sciencedirect.com/science/articl…

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Vlad Vyazovskiy@VVyazovskiy · Apr 18

Sleep homeostasis in lizards and the role of the cortex | PNAS pnas.org/doi/10.1073/pn…

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Yuval Nir 💔@LabNir · Apr 15

A time window for memory consolidation during NREM sleep revealed by cAMP oscillation: Neuron cell.com/neuron/fulltex…

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bioRxiv Neuroscience@biorxiv_neursci · Apr 4

Plasticity induction in the ventromedial prefrontal cortex during REM sleep improves fear extinction memory consolidation biorxiv.org/content/10.110… #biorxiv_neursci

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Brain and Sleep Research Laboratory@bsrlaboratory · Mar 27

ATP-sensitive potassium channels alter glycolytic flux to modulate cortical activity and sleep | PNAS pnas.org/doi/10.1073/pn…

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Brain and Sleep Research Laboratory@bsrlaboratory · Mar 25

Reversible reduction in brain myelin content upon marathon running nature.com/articles/s4225…

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Brain and Sleep Research Laboratory@bsrlaboratory · Mar 22

Enhanced memory despite severe sleep loss in Drosophila insomniac mutants journals.plos.org/plosbiology/ar…

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Brain and Sleep Research Laboratory@bsrlaboratory · Mar 21

Sleep pressure accumulates in a voltage-gated lipid peroxidation memory nature.com/articles/s4158…

bsrlaboratory's tweet card. Nature - Sleep-inducing neurons in Drosophila rely on Hyperkinetic, the β-subunit of the KV1 channel Shaker, to monitor sleep need by translating lipid peroxidation events into changes in the...

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