Brain Tumor News
@braintumor
Global Insights into Brain Tumor Care, Research, and Education
New Clinical Trial for Glioblastoma Patients! 🚨 We're excited to announce that Dr. Peruzzi has been approved to begin a Phase 1 trial for a new treatment targeting recurrent Glioblastoma. This trial is for patients who have tried at least one previous treatment and are eligible…
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Chen et al. compared MR perfusion characteristics of pseudoprogression in brain tumors treated with immunotherapy with pseudoprogression after chemo-radiation and radiation necrosis after radiation. #JNO Read more:link.springer.com/article/10.100…
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Read the lay summary or full article for “A phase II, open-label, single-arm trial of #pembrolizumab for recurrent #meningioma and solitary fibrous tumor” in our latest issue: bit.ly/41LhtCK
Blockbuster relative citation ratio on IDH mutant tumors. pubmed.ncbi.nlm.nih.gov/37272516/
For the first time, researchers used lab-grown organoids created from tumors of individuals with glioblastoma (GBM) to accurately model a patient’s response to CAR T cell therapy in real time. #pennmedicine #celltherapy Learn more: penntoday.upenn.edu/news/penn-medi…
When Karolina Atsalis was diagnosed with a brain tumor in 2021, her friends rallied around her, establishing the Smiley Fund and raising funds for the @MGHCancerCenter, where Karolina received lifesaving care. spklr.io/6013LOYf
Speaker Spotlight! Dr. Michael Lim, Professor and Chair of the Department of #Neurosurgery at @Stanford_Neuro, will present "Immune Cell Exhaustion in GBM." To learn more about our annual meeting and register, please visit: sfneurological.member365.com/public/event/d… #NeuroTwitter #Neurology #Neuro
Nice review by @BryanDChoi and team @MassGeneralNews nature.com/articles/s4169…
Study on skull base meningiomas treated with stereotactic radiotherapy (SRT): 52.9% showed symptom improvement. Key predictors: younger age (optic neuropathy), shorter symptom duration (extraocular), & lower radiation dose (trigeminal). [DOI: 10.1080/02688697.2024.2427720]
In a new @naturecomms publication, researchers from @MGHNeurosurg and colleagues created a blood-based assay for the detection of IDH1.R132H-mutant #gliomas. Read more: massgeneral.org/news/research-… @BalajLeonora @BobCarterMD
.@BalajLeonora @BobCarterMD @SmaheenBatool1 develop an RNA-based Droplet Digital PCR assay to detect key #IDH1 mutation in plasma biopsies from #glioma patients with high sensitivity #CancerResearch @NatResCancer nature.com/articles/s4146…
For patients: I have a headache...do I need an MRI? Headaches are common, but rarely signal a brain tumor. However, for those with tumors, headaches often accompany other neurological symptoms. Assess for red flags and consider neuroimaging. #BrainTumor #Headache #Neuroscience

For neurosurgeons, @MGBneurosurgery @MGHNeurosurg @BWHNeurosurgery make note of the Master Class led by @BrianNahed on intraoperative ultrasound. Register here web.cvent.com/event/ef4913e1…
We are pleased to announce the 4th Annual Update in Neuro-Oncology HMS CME course in live and virtual format. Please join us for a high impact three day overview of the latest in neuro-oncology! Please share the following link and information with students, trainees, and staff…
Strong work in @NEJM by Dr. Brastianos and my colleagues at @MGHNeurosurg and @braintumor! Lot's of promise for targeted therapy for papillary #craniopharyngioma patients using BRAF-MEK inhibition. @USCBTC #braintumor #neurosurgery #NeuroTwitter #oncology
Read "BRAF–MEK Inhibition in Newly Diagnosed Papillary Craniopharyngiomas," the NEJM Original Article referenced in this @statnews article: nej.md/3NQ0mHh
Brain Tumor Research: Did you know #craniopharyngiomas have a low mutation rate compared to other tumors? This lack of genetic complexity makes them susceptible to targeted therapies. More to follow on this in future posts.

May is Brain Tumor Awareness Month. Please considering joining @Rowrepublic and the Tagliente family in raising awareness to benefit neuro-oncologic research @MGHNeurosurg. Read more about their brain tumor journey here. because.massgeneral.org/rowrepublic
Congratulations to Dan Cahill, MD PhD, Vice Chair of Research @MGHNeurosurg for his promotion to @HarvardMed Professor of Neurosurgery! Dr. Cahill is an internationally recognized expert in neurosurgical oncology, with a special focus on IDH mutant glioma and research mentorship.
Liquid Biopsy for Brain Tumors is advancing rapidly. Many opportunities to combine approaches to optimize diagnostics and therapeutic monitoring.
