UW BRAIN Team
@brain_uw
The mission of the BRAIN Team is to improve neonatal neurodevelopmental outcomes through neuroprotection-focused research and clinical application.
Cooling blanket temp = HIE brain injury biomarker. A jaw-dropping aOR of 17.0 of death or moderate-severe NDI in HIE infants with a high cooling blanket temp. Great work by BRAIN Team members U. Mietzsch, @Neo_DrLaw, @DrRagnar, @mihai_pd and @SandraJuul1. @EBNEO @UW_SCH_Neos 🧠
Great work @mihai_pd, @DrRagnar, and @Neo_DrLaw!
This report from the PENUT trial showed that opioids and/or benzodiazepines used in extremely preterm infants are associated with adverse effects on 2-year neurodevelopmental outcomes. @DrRagnar @Neo_DrLaw @brain_uw ja.ma/2VgNti6
Congratulations BRAIN Team members @Neo_DrLaw, @DrRagnar, and @mihai_pd - working hard to learn about and protect neonatal brains from intracranial hemorrhage.
This report from the PENUT trial showed that opioids and/or benzodiazepines used in extremely preterm infants are associated with adverse effects on 2-year neurodevelopmental outcomes. @DrRagnar @Neo_DrLaw @brain_uw ja.ma/2VgNti6
RSVP for our 1st annual Research Day! Help us celebrate researchers from across the IHDD, including the Intellectual and Developmental Disabilities Research Center and University Center for Excellence in Developmental Disabilities on June 15, 2023! shorturl.at/ahU14
Collaborative @brain_uw work by neonatology, pediatric neurology, genetics, and neonatal ethics to raise awareness of and testing for genetic etiologies in neonatal encephalopathy distinct from HIE. @EBNEO @seattlechildren
Dr. Sarah Kolnik presenting data on how head circumference influences brain region captured by NIRS in preterm infants. Small head circumference may not reflect cerebral regional saturation. @brain_uw @SCNeonatal @D8Neonatal
Neonatology is "not able to accurately predict the results of complex long-term assessments...even when using rich datasets and advanced analytic[s]." Follow-up for premies is essential. Thankful to PENUT for collaboration w/@brain_uw - @DrRagnar @mihai_pd @Neo_DrLaw @SarahKolnik
![brain_uw's tweet image. Neonatology is "not able to accurately predict the results of complex long-term assessments...even when using rich datasets and advanced analytic[s]." Follow-up for premies is essential. Thankful to PENUT for collaboration w/@brain_uw - @DrRagnar @mihai_pd @Neo_DrLaw @SarahKolnik](https://pbs.twimg.com/media/FllG-UbaUAAHMVZ.jpg)
MILD HIE matters. Collaboration between Neonatology and Neurology is vital for advances in neonatal brain care and HIE. Keep up the great work, BRAINs! @UW_SCH_Neos and @uwpedsneuro
New article from our collaboration @seattlechildren between @UW_SCH_Neos and @uwpedsneuro authors.elsevier.com/c/1fOkX39uenfG…
Congratulations to BRAIN Team members and collaborators Ulrike Mietzsch and @SandraJuul1 for a well-done and important contribution to neonatal brain research. The search for neuroprotective agents continues @UWMedicine, @seattlechildren, @NeoNeuroLab, and across the globe #brain
Giving erythropoietin to newborns undergoing therapeutic hypothermia for hypoxic–ischemic encephalopathy did not result in a lower risk of death or neurodevelopmental impairment than placebo and was associated with more SAEs. nej.md/3z224iA
BRAIN Team members @mihai_pd and @Neo_DrLaw discussing NIRS monitoring in premies @D8Neonatal - #neoTwitter #NICU @DrRagnar @UW_SCH_Neos
Giving erythropoietin to newborns undergoing therapeutic hypothermia for hypoxic–ischemic encephalopathy did not result in a lower risk of death or neurodevelopmental impairment than placebo and was associated with more SAEs. nej.md/3z224iA
Our work w/PENUT data in @JPerinatology showing BP data for the 602 EPT infants w/out BP treatment, and high intercenter variability in how and how often BP is managed in the others. Still so many questions in this field. rdcu.be/cPQk2 @brain_uw @EBNEO @CHRI_ResearchNE
Our newest paper is out showing the use of a ferret whole hemisphere brain slice model to capture regional responses to injury and treatment seen in vivo! bit.ly/3CMBpF8 Always fun to collab with @NeoNeuroLab and @DrRagnar @BioTM_Buzz @UWChemE
It’s the final week of #HIEawarenessmonth and we have some really great events, storytelling and announcements this week! Tune in! #HopeforHIE #HopeInspiresCommunity #NeoTwitter #NeuroTwitter #NeuroNICU
Congratulations @Neo_DrLaw and @DrRagnar on your recent #brains publication!
Giving erythropoietin to newborns undergoing therapeutic hypothermia for hypoxic–ischemic encephalopathy did not result in a lower risk of death or neurodevelopmental impairment than placebo and was associated with more SAEs. nej.md/3z224iA
Lab director @DrRagnar is editing a special edition of @Life_MDPI - Diversifying and Strengthening Translational Animal Models of Newborn Brain Injuries. If that's your kind of thing, let us know! mdpi.com/journal/life/s…
Association of Increased Seizures During Rewarming With Outcomes ja.ma/3mZ0lDu team work 10 years from conception to completion @UTSWPedsGroup @UTSWNews @utswpediatrics @lina_chalak @Parkland @childrens @NewbornBrains
Yes! BRAIN Team is on 🔥. We do it for the 🧠 🧠 🧠 !! @mihai_pd @DrRagnar @Neo_DrLaw
Is this how we feel, @brain_uw ?
The hunt for neuro-predictive biomarkers continues, but Epo and Tau are giving us clues: Early Biomarkers of Hypoxia and Inflammation and Two-Year Neurodevelopmental Outcomes in the PENUT Trial. Congratulations @DrRagnar, @Neo_DrLaw 🧠 sciencedirect.com/science/articl…
So fortunate to collaborate with the ingenious @NeoNeuroLab. Congrats @DrRagnar and @Neo_DrLaw!
New paper from the lab! This model took 6+ years to develop and we hope it will be an important addition to preclinical developmental brain injury research. Super excited to see it in print! mdpi.com/1422-0067/22/1…
Neonatal Publication Highlight: Landmark HELIX trial led by @SudhinThayyil @CPN_NeoNeuro @imperialcollege published in @LancetGH with interesting results & massive implications for use of Therapeutic Hypothermia for HIE in LMICs. thelancet.com/journals/langl… #NeoEBM #Neotwitter