Omer Ali Bayraktar
@bayraktar_lab
Group leader at @sangerinstitute Neural diversity, spatial transcriptomics, glia, GBM http://sanger.ac.uk/group/high-thr…
How does tumour heterogeneity arise? How can we predict cancer cell plasticity? In 2 studies, we trace #glioblastoma heterogeneity to a spatial cancer cell trajectory w. atlassing bit.ly/4mkrWgs & predict plasticity w. snRNA/ATAC+deep learning bit.ly/3FbI6Ic 🧵
As a longtime humanitarian who has battled famines and hunger crises, I fear that starvation in Gaza has now passed the tipping point and we are going to see mass-scale starvation mortality. A thread on famine momentum, famine response, and what it means for Gaza today.
Doctors and health officials report wave of hunger deaths in Gaza on.ft.com/46iUoK6
I'm honoured to join @CRUK_CI and @Cambridge_Uni as a Junior Group Leader of AI for Cancer. My group will focus on reasoning, multimodality, hypothesis-making, and more to decode disease and health. A few positions are opened — consider applying to outsmart cancer together!
We are delighted to welcome @hana_aliee to the Institute. She joins as a Junior Group Leader and will lead her team in developing AI models to understand the molecular mechanisms driving health and disease. Find out more: cruk.cam.ac.uk/news/dr-hana-a…
Happy to share our new study from my PhD on the spread of farming across Anatolia and into the Aegean and then into Europe. @CompEvoMetu science.org/doi/10.1126/sc… 👇🏽
We are happy to be seeking three post-docs across Edinburgh Napier, Glasgow & UCL in an exciting project to investigate mechanisms linking glial ageing/longevity & neurodegeneration (MRC-funded). Positions advertised, info attached (til end of June) @FionaKerr_lab Nathan Woodling
Huge congratulations to Sam Behjati who has been elected as a Fellow of the Academy of Medical Sciences 🎉 Sam’s work is transforming how we diagnose and treat childhood cancers, and the Fellowship reflects his outstanding contributions to the field 🌟 sanger.ac.uk/news_item/sam-…
Great effort by @bayraktar_lab, @StatGenomics & @MoritzMall labs in unravelling GBM cell state variability and spatial organisation at single-cell multimodal resolution. Happy that we could also contribute to this fantastic study! #Glioblastoma #SingleCell #SpatialOmics
How does tumour heterogeneity arise? How can we predict cancer cell plasticity? In 2 studies, we trace #glioblastoma heterogeneity to a spatial cancer cell trajectory w. atlassing bit.ly/4mkrWgs & predict plasticity w. snRNA/ATAC+deep learning bit.ly/3FbI6Ic 🧵
What keeps cancer cells in check—and can we tame hem? In 2 collaborative preprints, we trace glioblastoma cell transitions in space and decode what regulates their plasticity 🧠👇 📍 Spatial & multi-omic atlas: biorxiv.org/content/10.110… 📍 Regulatory logic: biorxiv.org/content/10.110…
Truly excellent and important work
🧠 Excited to share my main PhD project! We mapped the regulatory rules governing Glioblastoma plasticity using single-cell multi-omics and deep learning. This work is part of a two-paper series with @bayraktar_lab , @OliverStegle and @MoritzMall groups. Preprint at end🧵👇