Akira Yoshida
@akiyosshii1
MD (Rheumatologist), PhD student @NMSrheumatology. Research interests in Myositis, autoantibodies, and ILD. Views my own. https://orcid.org/0000-0003-3590-1637
thrilled to share our latest work from @NMSrheumatology🇯🇵, highlighting a distinct cytokine profile of anti-MDA5-positive DM, with elevations of IFN-β and λ3. The combination of serum IFN-α, β, and λ3 levels could serve as a prognostic biomarker. #MDA5 doi.org/10.1038/s41598…
After success in RA, PsA, it's time to define & achieve remission/ low disease activity in Myositis. Here is our review on remission/low disease criteria and significant unmet need in myositis. Welcome feedback to develop & validate IIM remission ! sciencedirect.com/science/articl…
📢吉田晃先生の抗MDA5抗体陽性皮膚筋炎に関する研究論文が出ました。 他の皮膚筋炎、SLE、COVIDを対照とし、血中のバイオマーカーを比較解析。 ✅IFN-λ3はMDA5群で著増 ✅IL-6はCOVID群で著増 ✅IFN-α/βはMDA5群で増加 ✅IFN-α/βとIFN-λ3の上昇の有無の組み合わせでMDA5群は3つのクラスターに分類可能
thrilled to share our latest work from @NMSrheumatology🇯🇵, highlighting a distinct cytokine profile of anti-MDA5-positive DM, with elevations of IFN-β and λ3. The combination of serum IFN-α, β, and λ3 levels could serve as a prognostic biomarker. #MDA5 doi.org/10.1038/s41598…
Why is lung involvement so feared in #myositis? What’s the story behind “hiker’s feet?” Our latest episode dives into the data behind the CLASS project on anti-synthetase syndrome. LISTEN & LEARN → acr.tw/4egbOsI @ACR_Journals
Just how critical was the presence of interstitial lung disease among the CLASS study cohort? Dr. Faghihi Kashani explains why it became important HERE → acr.tw/4egbOsI
Thanks to @jrheum for accepting the article and inviting for the interview! Truly honored our article to be picked as Editor’s Spotlight ! Special Thanks to Anushka from India and Maha from Saudi - the emerging leaders in myositis.
Editor's Picks Spotlight Role of CD19 Chimeric Antigen Receptor T Cell Therapy in Idiopathic Inflammatory Myopathies 🖊️ Drs. Anushka Aggarwal, Maha Almackenzie and Rohit Aggarwal @Anushka2k7 @docrota 📖 jrheum.org/cgi/content/fu… 📽️ youtu.be/H2L91C4x_A0
Editor's Picks Spotlight Role of CD19 Chimeric Antigen Receptor T Cell Therapy in Idiopathic Inflammatory Myopathies 🖊️ Drs. Anushka Aggarwal, Maha Almackenzie and Rohit Aggarwal @Anushka2k7 @docrota 📖 jrheum.org/cgi/content/fu… 📽️ youtu.be/H2L91C4x_A0
Thank you so much for having us and the wonderful opportunity to present the data from our international collaborative effort. I am proud to be a member of the CLASS family!
NEW EPISODE! The CLASS project brings together global investigators to better define anti-synthetase syndrome. Hear from the authors about clinical domains, antibody testing, & what’s next in autoimmune disease research. LISTEN NOW → acr.tw/4egbOsI @ACR_Journals
New EULAR/ACR classification criteria for Antisynthetase Syndrome ✅ Anti-ARS antibodies & ILD are top drivers 🧪 ANA, SSA, MSA testing crucial to apply/exclude criteria 🧠 Score ≥5.5 + anti-ARS = definite ASyS ⏩ most weighted items = anti-ARS , ILD, myositis #EULAR2025
【EULAR2025報告】 EULAR-ACR、ARS抗体症候群の分類基準の発表 ✅ILDは最高得点の臨床変数(NSIP/OP)であり、ASySの特徴 ✅臨床領域:ILD、筋炎、関節炎 ✅血清学的ドメイン:抗ARS、抗Ro52/抗SSA、および細胞質ANAパターン #EULAR2025
🚨 NEW classification criteria for #ASyS #antisynthetasesyndrome presented by @docrota and @Lollo7770 ➡️ clinical domain ➡️ other clinical features ➡️ serologic domain Great achievement! 👏🏼👏🏼👏🏼 #EULAR2025 @eular_org @ACR_Journals @eular_ARD
Editor's Choice: Find our recent interview discussing the role of CAR T-cell therapy in myositis with Dr Earl Silverman from Journal of Rheumatology! 😀📞📽💡 Do check out the full article in Editor's pick spotlight! @docrota @jrheum jrheum.org/content/viewin…
Nice review article published this month in The Rheumatology Oxford Journal Treatment guidelines for idiopathic inflammatory myopathies in adults: a comparative review👇#myositis #Rheumatology #MedTwitter Full Ref included below
Dear Friends — Looking for a senior PhD-level Biostatistician (Europe/USA) for a global, prestigious, high-impact international project on Myositis. Funding is provided. Interested or know someone? 📩 [email protected]
Retrospective obs. study explored dynamics of autoantibodies over time in SLE. Results showed that anti-Sm/RNP and anti-dsDNA, in contrast to anti-SSA/SSB, frequently fluctuated and their levels can decrease following B cell-targeted treatment A&R doi.org/10.1002/art.43…
And We Will use it in the incoming Classification Criteria of antisynthetase syndrome: ASyS Important that from Now all will use this as official abbreviation
Update on Consensus nomenclature and abbreviation for anti-synthetase syndrome. Furst major step towards homogeneity in literature. 📚📚✅️
Anti-synthetase syndrome (ASyS): Consensus on nomenclature and abbreviation for anti-synthetase syndrome is now done. Everyone should use this nomenclature and abbreviation for the ASyS going forward: an IMACS project academic.oup.com/rheumatology/a…
Anti-synthetase syndrome (ASyS): Consensus on nomenclature and abbreviation for anti-synthetase syndrome is now done. Everyone should use this nomenclature and abbreviation for the ASyS going forward: an IMACS project academic.oup.com/rheumatology/a…
#膠原病 に伴う #間質性肺疾患 診断・治療指針2025 が本日発刊です。 初版の2020年版が発刊されてから5年間でこの領域は飛躍的な進歩を遂げています。今回も #日本リウマチ学会 から桑名正隆教授、#日本呼吸器学会 から近藤康博教授を始めとするエキスパートの先生方の委員会による編纂です。
April Arthritis & Rheumatology Clinical Connections •Neutrophil Activation Markers and RA Treatment Response to JAK1/2 Inhibitors •Clinical Characteristics of Anti-Synthetase Syndrome: Analysis from the CLASS Project acr.tw/426RTql