WoolfsonLab
@WoolfsonLab
Protein Design and Synthetic Biology research lab in the School of Chemistry, University of Bristol.
Watch Dek introduce the work we do here in the Woolfson group at Bristol on understanding the protein folding problem and de novo protein design youtu.be/AmHnkU7zzhY
🚛🧬 New paper on rXiv! We reveal how cargo binding activates kinesin-1 by dislocating the TPR shoulder — a key structural switch that unlocks motor movement. Happy reading! 🔗biorxiv.org/content/10.110…
Looking for PhD students to join the new Cross lab, using protein engineering and design to manipulate intracellular transport! swbio.ac.uk/biomolecular-a… Project 62 Get in touch if you're interested in joining us! Working with @WoolfsonLab @MarkDodding @BristolBiochem @BristolChem
Now at #SBUK24 we're straight onto Protein and Genome Design session with the first keynote from @WoolfsonLab exploring rational and computational protein design and applications in modifying cellular transport
Exciting opportunity to join the University of Bristol as a BBSRC-funded Research Associate (4 years) working between us and @MarkDodding's lab. The post is on designing de novo peptides and proteins using both rational design and computational design and protein biochemistry.

Great to see members of our Bristol-Syngenta award committee @Zhihang04505562 @apphillips98 and @SeraphimLeng sharing their experiences organising the award and how it has helped them developed soft skills for their CVs. You read all about it below!
During a PhD it can feel like research should be your sole focus, but gaining transferable skills like communication and organisation is important no matter your career plans. From outreach to event planning, here are some extracurricular ways to help. chemistryworld.com/careers/how-ta…
Excited to share our latest designed A3B3 α-helical barrels, revealing how subtle the heptad register shift impact helix orientation. Well done to @ChubbJoel @KIAlbanese and team @WakeChemistry @Macquarie_Uni Read more here biorxiv.org/content/10.110…

We are pleased to announce the release of The Protein Design Archive. Our comprehensive database of designed proteins highlights the triumphs and challenges of the field: pragmaticproteindesign.bio.ed.ac.uk/pda/ Preprint:biorxiv.org/content/10.110… @mjstam @MartaChronowska @WoolfsonLab #proteindesign
Excited to see our work in print at Nature Chemical Biology today! We are using protein/peptide design to manipulate the activity of kinesin-1 motors in cells. @MarkDodding @WoolfsonLab @BristolBiochem nature.com/articles/s4158…
I am so excited to share this news! I am extremely grateful and feel immensely privileged to return to the department where my fantastic professors and mentors taught me how amazing protein chemistry is and inspired and encouraged me to pursue academic research.
We are pleased to announce that Katherine Albanese will be coming back home when she joins our department as an Assistant Professor in August. Interested research students at all levels should take note! @KIAlbanese
Last week we said (a very difficult) goodbye to Dr @KIAlbanese. 3 years has passed since she joined us, she’s been such an inspirational leader and mentor. As Katherine starts her independent career @WakeChemistry, we cheer her on every step of the way. Go shine, Katherine!!💖🌟




This year's meeting will be on Modern Methods in Peptide Synthesis, to be held on 22nd Mar 2024, in honour of Dr Eric Atherton, one of the pioneers of the Fmoc solid phase peptide synthesis. As usual registration is free. pepsoc.uk