UCSF Bakar Aging Research Institute

We bring together UCSF scientists and clinicians to uncover mechanisms behind aging, develop novel diagnostic/therapeutic tools, and establish best practices for providing equitable care to older adults in our communities. geroscience.ucsf.edu

“It’s a paradigm shift to know that the silent X doesn’t stay asleep,” says Dena Dubal, a neuroscientist and neurologist at the University of California School of Medicine in San Francisco, who led the study. go.nature.com/3Di2d6K

Research from @ishahjain and colleagues published in @CellCellPress shows that HypoxyStat, can prevent or reverse #mitochondrial disease in a preclinical mouse model. bit.ly/4kh0csc

The X chromosome inherited from mom impairs cognition and speeds up brain aging. Check out our latest @Nature. @UCSFAging @UCSF nature.com/articles/s4158… nature.com/articles/d4158…

Check out T. Richard Parenteau's work in the Journal of Investigative Dermatology published in December! This study links the age-related increase in epidermis permeability with #inflammaging. Read the article here: bit.ly/4gVs8jg

🧩The next episode of the Stress Puzzle, featuring Dr. Megan Gunnar discussing puberty and stress system recalibrations, will be available January 28th. Catch up on previous episodes you may have missed! Access here or wherever you listen to podcasts!: stressmeasurement.org/podcast

Compelling data coming from a multi-institution collaboration that included our executive committee member @DJ_Laird! Looking forward to unlocking more naked mole rat secrets. biorxiv.org/content/10.110…

Interesting work by @YousinSuh, Marco Conti and colleagues published in @NatureAging. Multi-omic analyses revealed #mTOR signaling as a prominent #ovary-specific #aging pathway. nature.com/articles/s4358…

Check out Jin Young's insightful review on the similarities between pathologic senescent fibroblast populations identified in cancer and fibrosis. @UCSFAging Convergent evolution of senescent fibroblasts in fibrosis and cancer w... sciencedirect.com/science/articl…

Interesting collaboration coming from the @UCSFGouldLab and @TamaraAlliston lab to identify an unexpected role of #collagen type IV in bone biology in connection with #TGFβ bit.ly/3BxKlDy

@UCSFAging and the UCSF Hillblom Center for the Biology of Aging are proud to announce the recipients of our graduate student fellowship awards! Congratulations!

We'd like to congratulate Dr. @saralahue for receiving the @NIHAging Paul B. Beeson Emerging Leaders Career Development Award! Her studies aim to determine the mechanistic links between biological age, delirium, and traumatic brain injury.

Leonard Hayflick had an outstanding career, conducting research on aging for over 50 years. He joined @UCSF in 1986 as Professor in the Department of Anatomy. He passed away in his home at the age of 96. leonardhayflick.com/obituary/

Check out this podcast hosted by one of our past postdoc fellowship awardees @ryanlinnbrown! She is also an incoming assistant professor @TexasTech this fall. @UCSFPsychiatry

Quieting your #mind and getting some 'deep rest' can improve your chances for healthy #longevity by allowing your cells to redirect energy to restore themselves. 👀 👉 the article featuring @Dr_Epel and colleagues' research: magazine.ucsf.edu/power-deep-rest

We're excited to announce our recipients of the BARI postdoctoral fellowships! Congrats @JonathanBayerl @TuranAghayev @ColineArnould1 @JeremieRispal, Jery Joy, Kate Cavanaugh, and Gurcharan Kaur!

Excited to share our preprint: #CRISPR i-based screen of #Autism Spectrum Disorder risk genes in #microglia uncovers roles of ADNP in microglia endocytosis and uptake of synaptic material biorxiv.org/content/10.110… Read more from first author @OMTeter below:

A new publication by @param_p_singh in @CellCellPress suggests that diapause, a state of suspended development, evolved from remodeling of ancient gene paralogs and involves a distinct lipid profile. Read more here: bit.ly/3VbAk5k

Publication Alert! 📢 Work by Kenichi Toma from @xinduan's lab in @CellCellPress featuring beautiful images coming out of the Kim Lab @UCSF Ophthalmology.