David Vilchez
@TheVilchezLab
Biologist, Professor @CECAD_ @UniCologne @UKKoeln. We study aging, age-related diseases, stem cell biology and proteostasis. @thevilchezlab.bsky.social
New work from the lab @NatureAging!❄️Lowering body temperature extends #longevity. We find that cold-induced #proteostasis prevents #aging and aggregation of proteins that cause age-related diseases #ALS #HuntingtonDisease in C. elegans and human cells nature.com/articles/s4358…
We have a 4-year postdoc position open in our Research Unit on proteostasis! The project explores inter-tissue regulation using advanced proteomics approaches. Collaborative & interdisciplinary environment. More details & application here: jobs-uk-koeln.onlyfy.jobs/job/pktg6ivjss…
Happy to share our new preprint, where we find that anle138b reduces Huntingtin inclusions and improves disease phenotypes in #Huntington’s Disease models, showing its potential as an HD treatment. biorxiv.org/content/10.110…
Don’t miss this opportunity to join Gabriele’s lab! Exciting science!
#Job alert! A #postdoc position in my lab @CECAD_ @UniCologne is open until December 1st. We look for: enthusiasm, curiosity, scientific rigour, and a background in protein quality control, lysosome signalling, or the cell cycle. We offer: fully funded position, top European…
Another Nobel Prize for basic research in C. elegans 👏🏼👏🏼👏🏼
This year’s medicine laureates Victor Ambros and Gary Ruvkun studied a relatively unassuming 1 mm long roundworm, C. elegans. Despite its small size, C. elegans possesses many specialised cell types such as nerve and muscle cells also found in larger, more complex animals,…
This year’s medicine laureates Victor Ambros and Gary Ruvkun studied a relatively unassuming 1 mm long roundworm, C. elegans. Despite its small size, C. elegans possesses many specialised cell types such as nerve and muscle cells also found in larger, more complex animals,…
In @elife: Root cap cell corpse clearance limits microbial colonization in Arabidopsis thaliana doi.org/10.7554/eLife.… It was a pleasure to contribute to this work from Alga’s lab @Team_Zuccaro and @neto_flames
🔬 Exciting findings from @TheVilchezLab in @CellReports! ALS-mutant FUS variants interact with PARP1 & histone H1.2, driving neurodegeneration. Blocking PARylation or reducing H1.2 may offer new therapeutic hope! 🧠✨ #ALSResearch #Neuroscience 📃➡️ cell.com/cell-reports/f…
We have a postdoc/lab manager position available in our lab. The position is initially until December 2025 with the possibility to be extended until December 2032. If interested, please contact me or apply here: search.app/B8Jb9mbx5aNdAQ…
Congrats Dr. Bilican! Great job, excellent thesis defense! @CGA_age

A postdoc position is available in our lab to study ADP-ribosylation and ubiquitylation signalling! We are looking for someone with experience in structural biology and biochemistry. The application deadline is June 10th. my.corehr.com/pls/uoxrecruit…
#RidenWithBiden
We had a very good feeling about this. May the 4th be with you, America.