Lu-Yang Wang
@SynapticTweeter
If I can see it, I can patch it.
Very proud to share our latest work in collaboration with Amy Yang, Mike Salter, Sean Egan on Intersectin 1 as a pivotal molecule for controlling the emergence of calcium dependent replenishment of the readily releasable pool in developing central synapses.
A newly developed molecule could inform future therapies for stroke-related brain injury, finds #SKResearch in @Nature. Read ➡️ bit.ly/45Wh80h
This novel glutamate binding cavity can be exploited for development of stroke drugs, as exemplified by a new compound LK2 described in our paper.
Check it out: most beautiful images of vATPase with a surprising partner on live synaptic vesicles from my brilliant colleague John Rubinstein and his team at SickKids Reaearch Institute & University of Toronto! science.org/doi/10.1126/sc…
We are humbled to receive this award. We thank the MDBR and CACNA1A foundation for supporting our research.
Many congrats to Amy Yang for her new paper on the role of cerebellum in social recognition memory in Nature Communication published online: nature.com/articles/s4146…. So proud of my former trainees for their outstanding work and achievements.
Thrilled to be sharing the news of our latest grant award to @SamYoungLab @uiowa @IowaMed, signifying a crucial first step in the development of a future #GeneTherapy for #CACNA1A-related disorders. Check out his conversation with @PangkongFox here: youtube.com/watch?v=u3bBuW…
Pleased to share our paper in Neuron showing how Bilirubin acts as an agonist for TRPM2 and aggravates brain injury in stroke.| Home authors.elsevier.com/sd/article/S08…
awesome program
HI neuro people. This is a very exciting event! Please have your trainees submit their abstracts.
Was a pleasure to co-supervise Ke Lai (future post-doc of the Wang Lab) on this project. In our collaboration with Shanghai Jiao Tong University, we have uncovered ASIC channels as a target in treating Neonatal Jaundice. Check out our paper in @ScienceTM stm.sciencemag.org/content/12/530…
#ThrowbackThursday to 4 yrs ago, when I first began the important mandate I received from our PM @JustinTrudeau: to return science & research to their rightful place, after a decade of cuts & muzzling of scientists by the previous govt. Today, our decisions are based on evidence.
😍 #Want
Thanks Pierre Drapeau from @CRCHUM for this beautiful gift. I read a lot of these while at @ucatolica, @uchile and @Columbia but never from the original book. @ra2174 and the @ArayAlab are going to take good care of them.
RIP to my friend, mentor, and collaborator Professor Jim Howe of @YaleMed Pharmacology. Here we are sharing a laugh with Jim’s former student Stacy Irizarry. Neuroscience has just lost one of the great electrophysiologists of our generation but we will never forget Jim’s laugh!
Another successful collaboration with our colleague Dr. Julie Forman-Kay moves us closer to understanding activity-dep translation of silenced mRNA. Check out our new paper in @PNASNews on reversible mRNA granule formation by FMRP bit.ly/2Iz6ipS 🔬🧠 #SickKidsVsFragileX
Following in the steps of our mentors Dr. Harold Atwood & Dr. Milton Charlton to solve the mystery of synaptic heterogeneity, see our new story in @NatureComms : rdcu.be/bniFN #Nanodomainologists #SeeItPatchIt #SickKidsVsSynapticHeterogeneity
Talk about a tour de force, Sam Young Jr.'s lab @SamYoungLab has combined virology and neuroscience to challenge conventional wisdom on presynaptic Ca2+ channel regulation in this must-read paper. Congrats Sam! 🍾 Keep listening to the calyx of Held! 👂🧠 sciencedirect.com/science/articl…
Latest research from our lab. We are fired up about the findings and their implications on presynaptic regulation of neuronal circuits.
A tour de force from Lu Wang's lab @SynapticTweeter uncovering the roles of FMRP regulation of synaptic function and impact on cerebellar circuit output. From molecule, to synapse, to circuit and behavior with a translational impact. A definite must read. nature.com/articles/s4138…
One step closer to solving Autism Spectrum Disorders! DHA (from omega-3 fish oils) rescued autism-related symptoms in our lab. The publication is open-access for everyone to read in full nature.com/articles/s4138… #SickKidsVSFragileX