Swneke Bailey

So excited to see this paper on the stromal changes driving Barrett’s Esophagus progression to Cancer. A Herculean effort effort integrating scRNASeq/CODEX/ECM proteomics. Concerted changes in Epithelium and Stroma: a multi-scale, multi-omics... sciencedirect.com/science/articl…

Right on time for #sarcoma awareness month! Happy to share that our most recent work just published in @NatureComms 🎉 In this study we discover that #EZHIP is an ectopically expressed oncogene in a subset of high-grade #osteosarcoma tumors. nature.com/articles/s4146…

nature.com/articles/s4146…

Great seeing this manuscript in print on patient-specific esophagus cancer-organ chip. Complete clinical mimicry Excellent work by ⁦@PalSanjima⁩ ⁦@RIMUHC1⁩ with collaboration with ⁦@wyssinstitute⁩ ⁦@DonIngber⁩ …nslational-medicine.biomedcentral.com/articles/10.11…

Neoadjuvant Avelumab (PD-L1) + Docetaxel triplet in gastro esophageal adenocarcinoma- a highly effective regimen. It’s been a long 8 years since we launched this trial, good to finally see in print! cell.com/cell-reports-m…

WP3 of TREAT, speakers @Kong10Iris @PalSanjima have talked about ‘Neuroendocrine differentiation as a mechanism of chemotherapy resistance and how to target it’ and ‘Modelling tumour-micro environment interactions to assess novel treatment approaches’

Last week was an eventful week for the Division of Thoracic and Upper Gastrointestinal Surgery. We hosted our annual TREAT Canada in person meeting and the 7th annual symposium on Upper GI cancers. It was an honour to welcome so many incredible speakers @LFerri123

We kicked off the TREAT meeting with a ‘welcome and project overview’ by Dr. Ferri @LFerri123 and ‘Understanding and improving response to treatment in oesophagogastric cancer’ by Dr. Tim Underwood @TimTheSurgeon

During Work Package 1 session of TREAT Canada, Drs. Cools and Yeung have delivered talks on the ‘workflow and optimization - the MGH experience’ and an ‘ Update from Toronto General Hospital Site’

An excellent talk!

So thrilled to have @RousseauMC join our team @MThoracics @mcgillsurgery! Tremendous opportunity for us to grow as a group and for our fellows to benefit from his approach and experience! @ThoracicsCanada

We thank NCI for supporting our work in 3D cancer genomics! This work was led by our grad student Katie Mortenson, co-supervised by K-T Varley, with close collaborations from Yang Liu, @GertzLab , and @Sven_Bailey.

nature.com/articles/s4158…

#GUTImage from the paper by Zhang et al on "Recurrent RhoGAP gene fusion CLDN18-ARHGAP26 promotes RHOA activation and focal adhesion kinase and YAP-TEAD signalling in diffuse gastric cancer" via bit.ly/4eXjekF #GastricCancer

Very happy to see this story published. Congratulations to Ansley and @aki_zakis who co-led the study. Thank you to everyone involved. A great collaboration with Livia Garzia, Veena Sangwan, @LFerri123 and @xyzxiaoyang. aacrjournals.org/cancerres/arti…

Now online! TULIPs decorate the three-dimensional genome of PFA ependymoma dlvr.it/T9ND3b

New from the May issue— MYC #ecDNA drives acquired cross-resistance in #SCLC, by Shreoshi Pal Choudhuri, Michael Lawrence, @SihanSean, @BenDrapkin et al. bit.ly/3ywyZyb @CRI_UTSW @utswcancer @MGHCancerCenter @broadinstitute

Félicitations à Dre Nada Jabado, lauréate 2024 du Prix international @FondationLOreal @UNESCO @4womeninscience pour l’Amérique du Nord, qui révolutionne la compréhension des défauts génétiques responsables des tumeurs cérébrales pédiatriques agressives. tinyurl.com/mvpbv3bn

Great work by ⁦@JamieTankel⁩ demonstrating that non-regional retroperitoneal nodes in gastro-esophageal adeno can be treated successfully with curative intent surgery in select cases. ⁦@JournalofGISurg⁩ ⁦@SSATNews⁩ sciencedirect.com/science/articl…

I feel like it has been a while since we talked about #CancerStemCells - excited to present a new review with @MarcoGalloLab just out in @NeuroOnc on #GBM CSCs led by @AnthonyrSloan @DJ_Silver_PhD #BTSM academic.oup.com/neuro-oncology…