StainsFile

@StainsFile

Let’s talk about visualizing cells! 👩🏽‍🔬🔬 We’re an online resource for open-access protocols, reagents, theory, and more. Brought to you by @STEMCELLTech.

Joined October 2019

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StainsFile@StainsFile · Mar 4, 2024

Welcome to StainsFile by @STEMCELLTech! Here, you can enjoy easy and open access to all the protocols and supporting resources you need to help you fix, prepare, and stain specimens: stainsfile.com 👩🏽‍🔬💻🧫🔬 #cellstaining #histology #microscopy #microscopymonday

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StainsFile@StainsFile · Jul 25

Dr. Johann Danzl's team at @ISTAustria describe light-microscopy-based connectomics (LICONN) in their recent @Nature study. 🔬 LICONN allows for synapse-level phenotyping of brain tissue in biological experiments in a readily adoptable manner: go.nature.com/3H9WZva

StainsFile's tweet image. Dr. Johann Danzl's team at @ISTAustria describe light-microscopy-based connectomics (LICONN) in their recent @Nature study. 🔬

LICONN allows for synapse-level phenotyping of brain tissue in biological experiments in a readily adoptable manner: go.nature.com/3H9WZva

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StainsFile@StainsFile · Jul 16

🎧 How are changes in diagnostics affecting labs? Tune in to the On the Microscope Podcast from the @MayoClinic, where experts break down the biggest shifts in diagnostics and how they’re shaping clinical decision-making. 🎙️ apple.co/44owX0l #SciencePodcast

StainsFile's tweet image. 🎧 How are changes in diagnostics affecting labs?

Tune in to the On the Microscope Podcast from the @MayoClinic, where experts break down the biggest shifts in diagnostics and how they’re shaping clinical decision-making.

🎙️ apple.co/44owX0l

#SciencePodcast

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StainsFile Retweeted

Stem Cell Podcast@stemcellpodcast · Jul 8

Our next episode features Dr. James Briscoe (@briscoejames) from @TheCrick! Check out his team's @Nature paper developing a 3D model of human trunk formation: go.nature.com/4lzKF77

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StainsFile@StainsFile · Jul 23

PD-L1 IHC assays are FDA approved companion diagnostics that are critical to determine the PD-L1 expression levels in different tumors. 🖊️ Sign up for this @NS4Histotech webinar to hear recent updates about these assays: bit.ly/460HsZl

StainsFile@StainsFile · Jul 21

Need help with staining your epithelial organoids? Here's a protocol for immunostaining epithelial organoids from different tissues—including intestinal, mammary, prostate, lung, and pancreatic—after fixation: bit.ly/4nl9Uv3

StainsFile's tweet image. Need help with staining your epithelial organoids?

Here's a protocol for immunostaining epithelial organoids from different tissues—including intestinal, mammary, prostate, lung, and pancreatic—after fixation: bit.ly/4nl9Uv3

StainsFile@StainsFile · Jul 18

🚨 Add some more color to your live-cell, super-resolution, and electron #microscopy! Researchers from Fujian Medical University have developed an extremely stable monomeric RFP named mScarlet3-H. Learn more in @naturemethods: go.nature.com/3RWW3MP

StainsFile's tweet image. 🚨 Add some more color to your live-cell, super-resolution, and electron #microscopy! Researchers from Fujian Medical University have developed an extremely stable monomeric RFP named mScarlet3-H.

Learn more in @naturemethods: go.nature.com/3RWW3MP

StainsFile Retweeted

Modern Pathology@ModernPathology · Jul 16

We would wonder where this hepatocellular carcinoma with large nuclei would lie in the model reported this month: Patil A, Hasan B, Park BU, Smith L, Sivasubramaniam P, Elhalaby R, Elessawy N, Nazli S, DaCosta A, Shabaan A, Cannon A, Lau C, Hartley CP, Graham RP, Moreira RK. A…

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StainsFile Retweeted

Raza Hoda MD@RazaHoda · Jul 16

Case of Tubular Adenoma of Breast🔬 Tubular adenoma of breast is a benign mass composed of densely-packed round ductules with limited intervening stroma. No relation to the colon! #PathX #PathTwitter #breastpath

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StainsFile Retweeted

Héctor-Enrique Torres-Rivas, MD@duckhuca · Jul 15

🫁 Pleural effusion. 🔬 Negative. Category 2 The International System for Reporting Serous Fluid Cytopathology. 🪟 Reactive changes. Windows. #Cytology #CytoPath #PathX

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StainsFile Retweeted

Human Pathology@Human_Pathology · Jul 14

New in #HumPathol: Biliary adenofibroma and cholangiocarcinoma: neighbors or relatives? A systematic and critical review. sciencedirect.com/science/articl… #pathology #PathTwitter #PathX #liverpath

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StainsFile@StainsFile · Jul 14

🔹Resinous versus aqueous mounting media? 🔹How do you use refractive index and diffraction to make your images look their best? 🔹What's ringing media? Mounting specimens doesn't have to be insurMOUNTable. 😉 Read up on mounting media in #histology: bit.ly/45zeoIa

$StainsFile's tweet image. 🔹Resinous versus aqueous mounting media? 🔹How do you use refractive index and diffraction to make your images look their best? 🔹What's ringing media? Mounting specimens doesn't have to be insurMOUNTable. 😉 Read up on mounting media in #histology: bit.ly/45zeoIa$

StainsFile Retweeted

Allen Institute@AllenInstitute · Jul 11

Happy Friday! 😁🧫 When you study thousands upon thousands of cells, you're bound to find some patterns that make you smile. This image features a cell line that illuminates lamin B1, a protein in the nuclear envelope. #SciShots

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StainsFile@StainsFile · Jul 11

While 3D cell cultures can more accurately represent complex tissues, what's the best way to image them? Dr. Jonathan Liu's (@jonliu123) team at @UWBioE reviews both 2D and 3D #microscopy approaches for studying 3D cell cultures. @naturemethods: go.nature.com/4efXv7F

StainsFile's tweet image. While 3D cell cultures can more accurately represent complex tissues, what's the best way to image them?

Dr. Jonathan Liu's (@jonliu123) team at @UWBioE reviews both 2D and 3D #microscopy approaches for studying 3D cell cultures.

@naturemethods: go.nature.com/4efXv7F

StainsFile Retweeted

Human Pathology@Human_Pathology · Jul 9

New in #HumPathol: Triple-Negative Lobular Breast Cancer: focus on pathology and clinical challenges. sciencedirect.com/science/articl… #pathology #PathTwitter #PathX #breastpath

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StainsFile@StainsFile · Jul 9

🔬 The @AllenInstitute has launched OpenScope, a groundbreaking platform that gives researchers around the world access to powerful brain imaging tools. 🧠 See how you can propose an experiment—at no cost—in the Allen Brain Observatory: bit.ly/3HOMzS4 #OpenScience

StainsFile's tweet image. 🔬 The @AllenInstitute has launched OpenScope, a groundbreaking platform that gives researchers around the world access to powerful brain imaging tools. 🧠

See how you can propose an experiment—at no cost—in the Allen Brain Observatory: bit.ly/3HOMzS4

#OpenScience

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StainsFile Retweeted

Human Pathology@Human_Pathology · Jul 7

New in #HumPathol: BSND: An emerging immunohistochemical marker that reliably distinguishes benign from malignant oncocytic salivary gland tumors. sciencedirect.com/science/articl… #pathology #PathTwitter #PathX #ENTpath

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StainsFile@StainsFile · Jul 7

Do you have beautiful images of stained or dyed specimens that you’d like to share with the scientific community and beyond? 🖼️ Submit your image to StainsFile and contribute to a growing, open-access histology resource! bit.ly/3TwzWxB

StainsFile's tweet image. Do you have beautiful images of stained or dyed specimens that you’d like to share with the scientific community and beyond?

🖼️ Submit your image to StainsFile and contribute to a growing, open-access histology resource! bit.ly/3TwzWxB

StainsFile Retweeted

Ricardo Henriques@HenriquesLab · Jul 2

🔬👨‍💻📰 #SReD is out! Automated structural detection for #ImageJ & #FIJI, from nano to macro ✨🐘. No training data, no bias - texture analysis with GPU acceleration!⚡️ Brainchild of @afonsomendes92 and adventure w @christlet lab + friends. Check: nature.com/articles/s4146…

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StainsFile@StainsFile · Jul 4

New research shows nonlinear live-cell imaging is a powerful tool for studying myelin morphology in conditions like #MultipleSclerosis. 🧠 Drs. Marie Louise Groot and @ALuchicchi at @amsterdamumc show subtle white matter changes in neurological donors. bit.ly/4ilrk7a

StainsFile's tweet image. New research shows nonlinear live-cell imaging is a powerful tool for studying myelin morphology in conditions like #MultipleSclerosis.

🧠 Drs. Marie Louise Groot and @ALuchicchi at @amsterdamumc show subtle white matter changes in neurological donors. bit.ly/4ilrk7a

StainsFile Retweeted

eLife - the journal@eLife · Jul 2

How do cells clean up misfolded proteins when they divide? This study finds that the cleanup crew includes the ER chaperone BiP and the proteasome, and kicks in right as cells finish dividing. Surprisingly, one major cell cycle regulator isn’t involved. elifesciences.org/articles/96675…

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