Gregorio Spagni

Apheresis therapies in MOGAD: a retrospective study of 117 therapeutic interventions in 571 attacks jnnp.bmj.com/content/early/… @NeuroVisionLab

Very nice study comparing sensitivity and specificity of live vs fixed CBA for AQP4 and MOG Ab detection in clinical practice. Live CBA offers a big gain in sensitivity and help not miss real cases with the disease! onlinelibrary.wiley.com/doi/10.1002/ac… @ESotirchos @EoinFlanagan14 @chenmayo

neurology.org/doi/10.1212/NX… Proud to share @StefanoMascio91 latest work on PLP1 antibodies in demyelinating diseases. PLP1 abs are mainly found in patients with non MS diseases with combined central and peripheral demyelination, but also in rare seronegative NMOSD

Delighted to share @Lauz_Caccia et al #MOGAD epidemiology study: ➡️ 1st such population-based study in North America ➡️ Prevalence of 3.7/100K in Olmsted County & 2.61/100K in Martinique ➡️Trend towards increased incidence & recognition over time 👇 link.springer.com/article/10.100…

Cerebellar Involvement in Attacks of Aquaporin-4-IgG Positive Neuromyelitis Optica Spectrum Disorder | Neurology Neuroimmunology & Neuroinflammation neurology.org/doi/10.1212/NX… @dinoto_ale @Lauz_Caccia @eoi

IgG4-RD pachymeningitis often causes headache and cranial nerve problems, is best diagnosed with MRI and biopsy, and frequently relapses despite treatment. ja.ma/4eA5yKX

This is progress. Expert IWG #Alzheimers clinicians recommend against the disease-without-symptoms 'biologically defined' @alzassociation criteria and clarify that treating pathology doesn't necessarily mean treating disease. @nvillain_alz @LonSchneiderMD jamanetwork.com/journals/jaman…

Stop scrolling!!! 🤚 Terroba-Navajas et al. show that biophysical and functional features of auto-antibodies targeting Caspr2, are associated with distinct clinical syndromes within the spectrum of Caspr2-Ab-associated disorders🧑‍🔬🔬 authors.elsevier.com/sd/article/S26…

Great work by Lucia Campetella @luciacamp7 and team lead by Sergio Muniz Castrillo.

Very proud of @Ganesha_Li new paper! 1st diagnostic predictive test of a relapsing course in #MOGAD! With @darshi_r @Benjamin_Trewin @RussellCDale @marignierro @MasturaMonif @anneke_vdw, the Australasian #MOGAD group & many others not on X. Check it out: shorturl.at/eqLPW

A seminal preclinical study in @CellCellPress from Harald Prüß' group on a new approach to treat autoimmune encephalitis using CAAR-T cells! 👏sciencedirect.com/science/articl… dzne.de/aktuelles/pres…

The EAN SP Neuroimmunology invites you to take part in a survey on your knowledge and educational needs in neuroimmunology. Your input is really appreciated. @EANeurology @drBWillekens @AINI_neuro @GiannoccaroPia @damato_v @MGastaldi85 @LyonPNS_AE surveymonkey.com/r/SPNeuroimmun…

1/ 🎉 Excited to share our latest research on Chimeric Autoantibody Receptor (CAAR) T cells targeting NMDA receptor-specific B cells! This could be a game-changer for treating #NMDAR #encephalitis.@CellCellPress authors.elsevier.com/a/1i0edL7PXme0M #CAART #neuroscience #immunotherapy

1/ We are excited to share our report in @JExpMed showing that about 40% of cases of #WestNilevirus (#WNV) encephalitis are due to pre-existing auto-Abs neutralizing type I IFNs, making WNV encephalitis the best understood human infectious disease (rupress.org/jem/article/22…).

Fourth meningeal layer: The Subarachnoid Lymphatic-like Membrane (SLYM) science.org/doi/10.1126/sc…

Very excited to share our multicenter study on the relevance of CSF MOG-Abs testing. Thanks to all collaborators! 😊 @cobo_calvo @GeoArrambide @marignierro @EoinFlanagan14 @TheMOGProject @TheSumairaFDN @darshi_r @Raphael_BrdVlt @EliaSechi @FabienneBrilot n.neurology.org/content/early/…