Journal of Neurology, Neurosurgery and Psychiatry

How well do plasma Alzheimer’s disease biomarkers reflect the CSF amyloid status? Hazan et al set to answer the question, and it seems plasma assays can act as a proxy for spinal taps jnnp.bmj.com/content/early/… @jmschott

Is speech function lateralised in the basal ganglia? Evidence from de novo Parkinson’s disease suggests so jnnp.bmj.com/content/early/…

Multiple sclerosis reactivations after fingolimod discontinuation for pregnancy planning: In this observational study, most patients who discontinued fingolimod to plan or maintain pregnancy experienced disease reactivation, including multiple relapses or severe events requiring…

Investigating colour vision and its structural correlates 15 years following a first demyelinating event jnnp.bmj.com/content/early/…

There is a strong dose-response relationship between depression severity and dementia risk which appears to be specific to depression and not accounted for by other potential confounding factors. The temporality of the depression–dementia relationship suggests reverse causation…

In this wonderfully written review, Coleman et al provide a comprehensive update on current understanding of idiopathic intracranial hypertension pathophysiology. This one is a must-read! 🔎 👇 bit.ly/3Zkf9Bg

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Very important finding by Gagliardi et al using data from the UK Biobank shows that adult-onset Alexander disease is monumentally underdiagnosed and misdiagnosed jnnp.bmj.com/content/early/…

Qualitative systematic review on the lived experience of functional neurological disorder neurologyopen.bmj.com/content/7/1/e0…

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Left atrial appendage occlusion in patients with atrial fibrillation and intracerebral haemorrhage associated with cerebral amyloid angiopathy: a multicentre observational study and pooled analysis of published studies jnnp.bmj.com/content/early/… @UCLStrokeRes

Fewer relapses and worse outcomes of patients with late-onset myelin oligodendrocyte glycoprotein antibody-associated disease bit.ly/4hu0zxx

Plasma protein in cognitive decline and Alzheimer's disease are associated with Neuropsychiatric symptoms and improve prediction of future decline, therefore offering a potential biomarker. jnnp.bmj.com/content/early/…

Neuropathy with anti-myelin-associated glycoprotein antibodies: update on diagnosis, pathophysiology and management, by Min e al jnnp.bmj.com/content/early/…

Telomere length, in vivo Alzheimer’s disease pathologies and cognitive decline in older adults Older adults with relatively longer TL may have greater in vivo AD pathologies and experience more rapid cognitive decline, potentially mediated by brain tau deposition.…

Real-world multicentre cohort study on choices and effectiveness of immunotherapies in NMOSD and MOGAD bit.ly/42NTGmc

First validation of the novel Freiburg Neurointerventional Score purposely designed for use by emergency medical dispatchers for detecting anterior circulation large-vessel occlusion in patients with suspected stroke neurologyopen.bmj.com/content/7/1/e0…

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This study by de Mol et al shows that genetic risk for MS affects the immune response to Epstein-Barr virus infection in children from the general population and interacts with household parental smoking, resulting in lower total brain, subcortical grey matter, and thalamic…

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