Marc Erhardt
@Salmo_Lab
Bacterial geneticist @HumboldtUni studying assembly and function of a fascinating nanomachine - the bacterial flagellum
Interested in anti-bacteriophage defense systems? We have an open PhD position in cell biology of bacteria and bacteriophages: nature.com/naturecareers/…

Out Now! The structure of the complete extracellular bacterial flagellum reveals the mechanism of flagellin incorporation bit.ly/4nqcNe9 #Microbiology #Bacteria #Flagellum
"The structure of the complete extracellular bacterial flagellum reveals the mechanism of flagellin incorporation" Now published @NatureMicrobiol 🥳! rdcu.be/eugWM
I'm excited to share the newest preprint of the lab... the structure of the complete extracellular flagellum, our most favourite bacterial nanomachine! biorxiv.org/content/10.110… A result of a very productive collaboration with @BergeronLab and @BeebyLab !
Cold Spring Harbor Laboratory - absolutely humbled by the beauty of this place and the ubiquitous spirit of the Delbrück "phage group" era 🧬🌊🦪
Exited to share our preprint on the structure of a Salmonella contractile injection system 🥳 Wonderful work by first author @Rooshanie Ejaz and @CloudyKielkopf, @freddie__martin, @HangryHobbit, @RebrovaEva, great collab with @Salmo_Lab @UCPH_CPR #cryoem shorturl.at/QHLpm
And here it is, the completed BASEL collection finally published as early access in @PLOSBiology - see the thread for more details. 🤗🧬🎣
🚨 🧬 Updated preprint on the completed BASEL collection - what's new? Some fun with bacterial immunity and a new P22 relative infecting E. coli K-12. A thread 🧵
Join us and @Salmo_Lab to explore phage-bacteria interactions, with a strong focus on microscopy techniques. Looking for a motivated PhD student! 🔬 Interested? Apply here 👉 [nature.com/naturecareers/…] 🔄 Please re-share to spread the word!
With @jrpenades, we challenged AI co-scientist @GoogleAI to generate hypotheses. In just 2 days, it recapitulated our unpublished, experimentally confirmed mechanism for how cf-PICIs spread between bacterial species! 🤯 @imperialcollege @FlemingCentre tinyurl.com/3byyaeh2
Our paper out @Nature: CARD domains mediate anti-phage defense in bacterial gasdermin systems CARDs are essential for caspase recruitment in inflammasome activation. We now find them in bacterial immune systems Congrats @TanaWein! Thanks Kranzusch lab! tinyurl.com/CA88DD
Internationales Forschungsteam beschreibt erstmals die Struktur und Funktionsweise des Zorya-Systems, eines hochspezialisierten antiviralen Schutzmechanismus gegen Bakterien nature.com/articles/s4158… @Salmo_Lab @__jphilipp Bild: Frederick J.O. Martin/ Universität Kopenhagen
🦠 Neues bakterielles #Immunsystem entschlüsselt: Ein internationales Forschungsteam um @Salmo_Lab & @__jphilipp der #HumboldtUni beschreibt nun erstmals die #Struktur und #Funktionsweise des Zorya-Systems in der Fachzeitschrift @Nature! Mehr Infos 👉 hu-berlin.de/de/pr/nachrich…
Thrilled to share that our collaborative work, led brilliantly by @HaidaiHu, is now published in @Nature! Huge thanks to the incredible @NMITaylorLab team - it was a joy to work with you. Grateful to @Salmo_Lab, @SimonJacksonNZ, and @AHarms485 for their invaluable contributions!
Very happy our paper on Zorya anti-phage defense system is now published in @Nature! 🥳 Big congrats to first authors @HaidaiHu and @__jphilipp and all other authors! Wonderful collab with @Salmo_Lab and @SimonJacksonNZ #cryoEM @UCPH_CPR @koebenhavns_uni nature.com/articles/s4158…
Our work describing the structure and mechanism of the Zorya anti-phage defense system is finally out @Nature! Led by @HaidaiHu and @__jphilipp in a wonderful collaboration with @NMITaylorLab, @SimonJacksonNZ, @AHarms485 et al.! nature.com/articles/s4158…
Evolutionary necessity for immune innovation harnessed components of the bacterial flagellar motor into a wild defense system - Zorya One of the most intriguing and sophisticated bacterial defense systems out there Congratulations Nicholas Taylor and colleagues!
Very happy our paper on Zorya anti-phage defense system is now published in @Nature! 🥳 Big congrats to first authors @HaidaiHu and @__jphilipp and all other authors! Wonderful collab with @Salmo_Lab and @SimonJacksonNZ #cryoEM @UCPH_CPR @koebenhavns_uni nature.com/articles/s4158…
Beautiful work on a crazy anti-phage system!
Very happy our paper on Zorya anti-phage defense system is now published in @Nature! 🥳 Big congrats to first authors @HaidaiHu and @__jphilipp and all other authors! Wonderful collab with @Salmo_Lab and @SimonJacksonNZ #cryoEM @UCPH_CPR @koebenhavns_uni nature.com/articles/s4158…
Huge congrats @HaidaiHu @VKleinSousa @AritzRoa @freddie__martin @yongwangKU @AHarms485 et al. 😃!
Thrilled to share that our Zorya paper is now published online in Nature! It was an incredible team effort @__jphilipp @Salmo_Lab @SimonJacksonNZ —thank you to everyone who contributed to this work.@IngaTrails @VKleinSousa @AritzRoa @freddie__martin @yongwangKU @AHarms485 @others
Very happy our paper on Zorya anti-phage defense system is now published in @Nature! 🥳 Big congrats to first authors @HaidaiHu and @__jphilipp and all other authors! Wonderful collab with @Salmo_Lab and @SimonJacksonNZ #cryoEM @UCPH_CPR @koebenhavns_uni nature.com/articles/s4158…
Bacterial small RNA makes a big impact for gut colonization Monzel & Desai @LIH_Luxembourg highlight work of @MoualiYoussef @StrowigLab IDing SrcF, sRNA from S. copri that promotes colonization by regulating bacterial degradation of dietary carbohydrates cell.com/cell-host-micr…
Gratulation! 🙌 Das Forschungsvorhaben RESYDE, geleitet von #HU-Prof. Dr. Kerstin Kaufmann, erhält einen @ERC_Research Synergy Grant für die Entschlüsselung komplexer Musterbildungsprozesse in biologischen Systemen in Höhe von 10 Millionen Euro. #ERCSyG 👉hu-berlin.de/de/pr/nachrich…