Steve Jackson Lab
@SPJacksonGroup
Our research focuses on the DNA damage response and its links to health and disease
We are so excited to see this collaboration now published
Happy to share that our recent work on the role of USP37 in counteracting the ubiquitylation and premature disassembly of stressed replisomes by TRAIP is now out. A fantastic collaboration with Olga Kochenova in @FrogWalterLab,@GS_Lab_Bham,@SPJacksonGroup nature.com/articles/s4146…
We're very proud of what we've achieved through our partnership with @AstraZeneca. We've made progress for patients, we've trained brilliant young scientists and we've helped to build a world-leading life sciences cluster. Here's to the next 10 years 🤝…
Research Assistant (Jackson Group) (Fixed Term) @Cambridge_Uni jobs.cam.ac.uk/job/50998/
A must for all DNA repair aficionados! Egmond DNA Repair Meeting → April 19–24, 2026 🇳🇱 ✔️ Confirmed top speakers ✔️ Ample opportunities for talks & posters Don’t miss it: dnarepairmeeting-egmond2026.com
Exciting opportunity for @ASTARsg student @GangGoh to exchange new ideas on #CRISPR and #BaseEditing with @SPJacksonGroup members past @durocherlab, and present #CRISPR25 @eventsWCS
Early bird registration deadline less than two months away. Check out this great line up @TheBACR 65th Anniversary Meeting.
Present your CRISPR research on a global stage!🧬✂️ Share your #GeneEditing insights with peers interested in learning more about applying #CRISPR approaches for modulating the genome at scale. #CRISPR25 ⏰Abstract deadline: 4 February 📎 Find out more: bit.ly/3Amz34N
Don't miss this opportunity to learn about #CRISPR from world experts including Thijn Brummelkamp @NKI_nl, @durocher1, @erika_alden_d, @LeopoldParts @sangerinstitute and Weixin Tang @UChiChemistry. Bursary application deadline 14 Jan, abstract deadline 4 Feb. Tell your friends!
Make your mark on the future of #PrecisionMedicine at #CRISPR25 Showcase #CRISPR methods for modulating the genome at scale🧬 Submit an abstract by 4 February for an opportunity to build your professional profile at the forefront of a global community 📎bit.ly/3Amz34N
This exciting novel discovery, published in @NatureComms, with contributions from the Balasubramanian lab @ChemCambridge, was supported by @CR_UK, @TheMarkFdn, @wellcometrust and @ERC_Research.
Happy to share our newly published article in Nature Communications! In this work, we uncover the novel role of KLF5 in sensitizing cells to ATR inhibition, identifying it as a synthetic lethal partner with the tumor suppressor ARID1A. @SPJacksonGroup nature.com/articles/s4146…
📡Registration is open for the Cambridge Precision Breast Cancer Symposium on 28 March! We are excited to have another stella line-up including keynotes from Steve Jackson @SPJacksonGroup and Simon Knott from @CedarsSinaiMed. Register here: qrco.de/pbci-events #CPBC2025
Our new paper led by @ASTARsg PhD student @GangGoh, uncovers a TDP1 splice-site mutation that makes HAP1 cells hypersensitive to #Topoisomerase I inhibitors. Find out how this could impact your #CRISPR screens and use of HAP1 cells @NAR_Open, bit.ly/3OWmmRN
Don't miss this opportunity to apply for a grant to attend @Fusion_Conf in Lisbon next year
We are excited to share this new review, everything you ever wanted to know about transcription-coupled DPC repair from leaders in the field @cjcarnie and @stingele_lab
Happy to share our newly published article in Nature Communications! In this work, we uncover the novel role of KLF5 in sensitizing cells to ATR inhibition, identifying it as a synthetic lethal partner with the tumor suppressor ARID1A. @SPJacksonGroup nature.com/articles/s4146…