Giuseppina D'Alessandro

Happy to share that our recent work on the role of USP37 in counteracting the ubiquitylation and premature disassembly of stressed replisomes by TRAIP is now out. A fantastic collaboration with Olga Kochenova in @FrogWalterLab,@GS_Lab_Bham,@SPJacksonGroup nature.com/articles/s4146…

Thrilled to see our work on murine oesophageal #Epithelioids published in @NatureGenet, after many years of hard work alongside @AlbertHerms during our postdoc at Phil Jones' lab @Sangerinstitute and built on the foundational work by @MariaPAlcolea nature.com/articles/s4158…

Check out this great work from my amazing colleagues @cjcarnie, Chloe Palma-Chaundler and Max Gotz in another fruitful collaboration between @SPJacksonGroup and @stingele_lab!

We are excited to share our new study in @NatureCellBio revealing that Cockayne Syndrome proteins CSA and CSB are required for the repair of toxic DNA-protein crosslinks (DPC) and we describe a novel transcription-coupled DPC repair pathway, nature.com/articles/s4155…

New DPC goodies for your Christmas stockings ! 🎄 🔔 Congrats @cjcarnie and co.! We love TOPORS biorxiv.org/content/10.110…

We made it! Our latest manuscript is now live in @NatureComms, give it a read! nature.com/articles/s4146…

Latest paper from Artios, describing our suite of DSBR reporter assays! academic.oup.com/nar/advance-ar…

Happy to share our work showing that RAD54L2 promotes genome stability by countering the formation of toxic TOP2 cleavage complexes. Great teamwork with @SPJacksonGroup @guidozagnoli @almuseben @SciencePrawn D. Morales and with P. Beli and J. Nitiss groups science.org/doi/10.1126/sc…

And if you want to join the team, check out cruk.cam.ac.uk/job/research-a…

Celebrating with our @aldo_bader on his @wellcometrust Early-Career Award, to continue his exciting research into defining the mutagenic impacts of #DNA resection during double-strand break repair. Congratulations 🥳

Our latest Review on CRISPR-Cas9 screen contributions in the #DNADamageResponse field is now available at @NatRevMCB ! Co-Written with @SPJacksonGroup, @SamahAwwad3, John Thomas and @vg29029 :)

The RING sparkle enlightens a new route for BRCA1 recruitment to DNA lesions. PreLight by @GiuseppinaDAle9 on a new preprint from @durocher1 prelights.biologists.com/highlights/two…

Exciting opportunity to join a fast growing biotech with a focus on developing new DDR inhibitors fro cancer therapy! #biotech #drugdiscovery #research #DDR artiospharma.com/career/scienti…

FUSzy ways of DNA damage response. prelights.biologists.com/highlights/fus… By preLighters @ram_ssrc and @GiuseppinaDAle9 on preprint from @levonebr et al. with author's response

Don't forget to check out @preLights - the preprint highlights service supported by our publisher @Co_Biologists. Our community of scientists select, highlight and comment on preprints they feel are of particular interest to the biological community: ow.ly/EVGi50D8qUZ

Online now! A #natural single-guide #RNA that directs Cas9 to #transcriptionally repress its own #promoter bit.ly/2JXD71l

Endogenous DNA breaks at neuronal enhancers: novel links to neurodegeneration? Great fun writing this preLight with @ram_ssrc. prelights.biologists.com/highlights/neu…