Robert Zitterbart🇺🇦
@RobZitterbart
Director R&D of PECS, Inventor of PEC, PhD, father and bio-organic chemist with love for peptides, proteins and other bio-molecules, views my own
I proudly announce the acquisition of Belyntic's Peptide Easy Clean (PEC) Technology by @mesalabsinc. I go along to @GyrosProteinTec to show the world the power of PEC. @belyntic will continue to develop peptide vaccines solely from now on next door. Read more in 🧵 below:
Alternative #PhD projects available below👇 Please RT♥️ Thanks!
#PhDposition 👩🔬🧑🔬available Do you have a strong background in #organicchemistry + #biochem experience? Interested in working #chembio interface? PhD for #RNA & industry collaboration - deadline 05.05 - Application online stellenangebote.uni-marburg.de/jobposting/5b4… Please RT♥️Thanks!
Here it is!!! This is our first contribution to antimicrobial peptides under the frame of a collaboration. Thank you @pandi_amir @SyborgLab @erblabs from us kudos to Frank & @miomiomarco Stayed tune because Marco has another antimicorbial project in the pipeline.🚀
Excited to share that our work @erblabs, rapid development of AI-designed antimicrobials via cell-free biosynthesis is out @NatureComms. 🙏 collab. with @OlallaLab, @HummerLab, @iLung_Marburg, @Uni_MR, @manishmicrobe, @HelgeBode_Lab, Bundeswehr Microb. nature.com/articles/s4146…
Online now @Chem_CP #INCYPRO stabilized protein complexes with • unprecedented chain topology • reduced aggregation tendency • exceptional longevity doi.org/10.1016/j.chem… Big congrats to the @VU_Science & #incircular #startup team! Supported by @ERC_Research & @EUeic!
Accepted in @NatureComms !! 🤩🤩Thanks Amir & Tobi for making us part of such a great story❤️ #antimicrobial #peptides From us credits go to @miomiomarco &Frank!🧑🏽🔬👨🏼🔬Stay tuned, release soon!👀 Also, our lab is baking🔥small antimicrobial peptides🔥You'll see!Exciting!🚀 #ProfLife
Thanks to the great teamwork with our collaborators, in this preprint we demonstrate how a combination of cell-free protein synthesis and deep learning can accelerate devolvement of de novo antimicrobials
Pleased to share our latest work, which was just published in @ChemicalScience. Benzylation of biomolecules in a MAT/MTase cascade. Applied to mRNA, you affect translation and immunogenicity. Congratulations to all authors 🎉 @EnzymeNicoCorn, @RMineikaite pubs.rsc.org/en/content/art…
I’ll do a full thread next week, but I’m ecstatic that our latest paper is published in ACS Chemical Biology @ACSBioMed! Phosphothreonine is a uniquely ordered amino acid. There is a fundamental, inherent difference between Thr and Ser phosphorylation. pubs.acs.org/doi/10.1021/ac…
Excited about ultrarapid drug discovery platforms? Check out our @J_A_C_S Perspective pubs.acs.org/doi/10.1021/ja… on Advances in Ultrahigh Throughput Hit Discovery with Tandem Mass Spectrometry Encoded Libraries by Edith v.d. Nol and @mm_a_t_a @UniLeiden @LED3hub @LeidenScience
"Reliable protein-protein docking with AlphaFold, Rosetta and replica-exchange" Some promising results on antibody-antigen complex prediction biorxiv.org/content/10.110…
Check out the PTM detection method from my lab by Benjamin Emenike. Multicomponent Oxidative Nitrile Thiazolidination Reaction for Selective Modification of N-terminal Dimethylation Posttranslational Modification | pubs.acs.org/doi/10.1021/ja… #jacs @acsJACS
How to convince an enzyme to work under denaturing conditions? Check out our #INCYPRO stabilized Sortase #OpenAccess @BioconjChem pubs.acs.org/doi/10.1021/ac… Congrats to the whole team @VU_Science & #incircular! Thanks for support by @ERC_Research @EUeic & @NWOFunding!
Coming soon: Chemiluminescence phenoxy-1,2-dioxetane luminophores for multiplex analysis of enzymes and bioanalytes...
Wow cool stuff, we often see cis trans isomers with proline containing peptides. Good to have more insights. Thank you @Dr_CR_Coxon
Great to see this paper (finally) published - thanks @ChemEurJ! Here we designed model peptides containing 4-F-Phe as 19F NMR reporters of proline conformation & show how neighbouring residues affect %cis-Pro. See below to find out more! @paddy_killoran @GSHanson @RSC_PPSG
Insightful review by the @GothelfLab in @ChemBioChem. They discuss chemotypes that can be used for bioconjugation to lesser used amino acids (essentially any amino acid but Cys, Lys and Tyr). Interesting overview of a large variety of chemistries. doi.org/10.1002/cbic.2…
Compact hydrophilic electrophiles enable highly efficacious high DAR ADCs with excellent in vivo PK profile New 🔥#ChemSciHOT🔥 article from Marc-André Kasper, Christian P. R. Hackenberger et al. ➡️ ow.ly/k0pC50MGHVJ 📌 @PhosphorusFive | @HumboldtUni
We proudly announce the acquisition of Belyntic's Peptide Easy Clean Technology by US-based company Mesa Laboratories, Inc.⭐️⭐️⭐️