Pilar Cossio
@PilarCossio2
#BPS2026 T&C subgroup award nominations are closing soon! please submit !!
@BiophysicalSoc T&C Subgroup, nominations due in a few weeks! Let's celebrate the contributions that are shaping our field 🎉🧬💻🔬
Check out our latest preprint for the first community #cryoEM heterogeneity challenge 🎆🎇 @sonyahans @miroastore + method developers and participants!
That's a wrap! The results of the first #cryoEM heterogeneity challenge are up on biorxiv! biorxiv.org/content/10.110…
Check out our recent preprint 👇on counting particles to estimate populations in #cryoem: noise can bias the estimates; with @lukeevanshandle & a great team. biorxiv.org/content/10.110…
#APSSummit25 come to our session in generative modeling and machine learning in chem phys! Chaired with @GrantRotskoff and an amazing set of speakers 🎉 starting Thursday 11:30am room 204A

We are hiring a Flatiron Research Fellow in the Structural Molecular Biophysics team! Experience with cryoEM and/or membrane protein simulations are a plus! Happy to chat in person with anyone at #bps2025 ! apply.interfolio.com/160227
Excited for #bps2025! Check out what SMBp has been up to at these talks and posters! (Also follow me at the other place.) @miroastore @samsledzieski @a_anand_ojha
1/ Thrilled to announce Dr. Elizabeth Wright from @UWBiochem as the inaugural winner of the June Almeida Award for #cryoem! 🎉Elizabeth’s pioneering work in both cryo-ET methods and structural virology made her a perfect fit for this award. Congrats, @erwright73! ❄️🔬
#NeurIPS2024 check out our work: Cryo-EM images are intrinsically low dimensional at the MLSB workshop with @lukeevanshandle Octavian-Vlad Murad @DingeldeinLars @CovinoLab & Marina Meila mlsb.io/papers_2024/Cr…
Cryo-EM @BiophysicalSoc please make your nominations for the Cryo-EM subgroup; the deadline is coming soon:
Hello @BiophysicalSoc Cryo-EM Subgroup Members, As we approach the 2025 Biophysical Society Annual Meeting in Los Angeles, we need nominations for 5 Cryo-EM Subgroup leadership positions. This is a great chance to become more involved with the Society and to support the Cryo-EM…
CryoEM community: we encourage you to submit applications to the Almeida Award #cryoEM BPS subgroup:
Mark your calendars for the BPS CryoEM Subgroup Symposium, on Subgroup Saturday at @BiophysicalSoc Annual Meeting 2025! Also, we have a new award, the Almeida Award, for a mid/senior level woman who has made outstanding contributions to #cryoem. See you there!
** Job Alert**: Are you looking for a postdoc in computational physics (including statistical mechanics, biophysics, fluid mechanics, quantum physics, and molecular dynamics), apply to CCM at the Flatiron Institute apply.interfolio.com/155357
Excited to share the first project from my postdoc. We studied a ligand bound TRPV1 cryo-EM dataset with state of the art heterotgeneity methods, and developed a way to compare them with a technique we call CryoSVD. paper doi.org/10.1101/2024.1… CryoSVD github.com/flatironinstit…
Dear cryo-EM women scientists, We want to honor you and your contributions at BPS 2025. This year, the Cryo-EM subgroup will honor a mid/senior-career woman scientist as the inaugural June Almeida awardee. June Almeida is the virologist who first discovered the coronavirus in…
Mark your calendars for the BPS CryoEM Subgroup Symposium, on Subgroup Saturday at @BiophysicalSoc Annual Meeting 2025! Also, we have a new award, the Almeida Award, for a mid/senior level woman who has made outstanding contributions to #cryoem. See you there!
I'm very happy to be part of this amazing collaboration: Dynamic allostery drives TGF-β signaling. Congratulations: MJ, @PhuKhanhTang Steve Nishimura @yifan_ucsf + co-authors 🎉🎉🎉
Dynamic allostery drives autocrine and paracrine TGF-β signaling: Cell cell.com/cell/fulltext/… A new dynamic allostery model of avb8 mediated TGF-b activation, result of a 10+ year collaboration with Steve Nishimura lab at UCSF. Congratulation to MJ, Rob and all co-authors!
Cryo-EM heterogeneity analysis needs benchmarks and validation tools. We're very happy to share CryoBench 🧊🪑: cryobench.cs.princeton.edu lead by the amazing EZ team @MinkyuJeon19791 @ZhongingAlong with FI @miroastore geoff woollard @sonyahans
🚀 Excited to share our preprint: CryoBench 🧊🪑: Diverse & Challenging Datasets for the Heterogeneity Problem in Cryo-EM! 🌐cryobench.cs.princeton.edu 🙌 Huge thanks to my amazing co-authors, collaborators, & advisor @zhongingalong! 🎉 #cryoEM #MachineLearning 🧵 Details below!
Was great to continue our SMBp tradition last night of supporting the Staten Island @FerryHawks! This year we brought along Niko Grigorieff for his first ever baseball game!
Check out our cryo-EM simulation-based inference work for amortized template matching: train with simulations, test with experimental images! biorxiv.org/content/10.110… with an amazing team @DingeldeinLars DavidSilva @lukeevanshandle @EdoardoDImprima @GrigorieffLab @CovinoLab 🎉🎉
Amortized template-matching of molecular conformations from cryo-electron microscopy images using simulation-based inference From @PilarCossio2 and @CovinoLab
Interested in calculating transition rates from biased simulations using bad coordinates? Check out our new preprint with Nico Mazzaferro & @glenhocky: arxiv.org/abs/2403.10668
Join us #BiophysicsWeek #CryoEM subgroup with the amazing Bridget Carragher:
For Biophysics Week, please join the BPS #CryoEM Subgroup for a webinar by Bridget Carragher, Technical Director of the Chan Zuckerberg Imaging Institute! When: March 20th, 4pm EST Where: Zoom - free registration, but signup required: columbiacuimc.zoom.us/meeting/regist… More in flyer 😊