Pardis Sabeti
@PardisSabeti
Professor @harvard @HarvardChanSPH @broadinstitute using genomics to impact infectious disease. Views are my own. @sabeti_lab @1000daysband
If you love #viruses, #ribosomes, and genomic #darkmatter, this thread is for you!! 💫 We're excited to share our published work developing Massively Parallel Ribosome Profiling (MPRP), which uncovered ~4,000 hidden proteins in ~700 viral genomes. science.org/doi/10.1126/sc…
Sharnig a #studymix2025 🎶— for @Harvard students grinding through finals 📚 #AgainstAllOdds #Statistics students prepping for #APStatistics exams 🧮 & good people everywhere wrapping up the year 🙌 —some new and old favorites that keep me inspired and grooving💥…
🚨We’re hiring 🚨a Bioinformatics Software Engineer to scale up viral detection pipelines on DNA- and RNA-seq data! The role involves machine learning, lots of cloud computing, and contributions to open-source tools. If this sounds fun or you know someone, please reach out!
Author selfie — but this one feels different. Our newest @sabeti_lab paper came out in Science just as conflict escalated between Israel and Iran, Shira’s and my birth countries. A painful reminder of how fragile the world can be. But also a reminder of what’s possible: that…

📷 Our latest work 📷: We developed Massively Parallel Ribosome Profiling (MPRP), a technology that reveals thousands of hidden viral proteins across ~700 viruses. With H5N1, mpox, and measles outbreaks rising, MPRP enables fast, safe, and large-scale protein discovery…
Had a wonderful time chatting with @PeaseRoland @BBC about our study uncovering thousands viral proteins — thank you for the opportunity to share our work with the broader public!! 🙏 bbc.co.uk/sounds/play/... @PardisSabeti @ScienceMagazine @broadinstitute @harvardmed
Thank you @carlzimmer @nytimes for covering our new study and the miraculous universe of microproteins! 💫 nytimes.com/2025/06/12/sci… @PardisSabeti @ScienceMagazine @broadinstitute @harvardmed
Thank you to @mohs_sl National Public Health Agency for their inspired leadership in the #mpox response and to Danaher for supporting them by donating 10,000 Cepheid Xpert diagnostic tests

Sierra Leone is battling an mpox variant, G.1, that is rapidly spreading—25% hospitalized, thousands likely infected, cases doubling every two weeks, and now detected in the US & Europe. The country is responding. The world must join them. @TIME @christian_happi…
Today, we’re announcing the first major discovery made by our AI Scientist with the lab in the loop: a promising new treatment for dry AMD, a major cause of blindness. Our agents generated the hypotheses, designed the experiments, analyzed the data, iterated, even made figures…
🎉 Big congrats to Dr. Laura Luebbert (@NeuroLuebbert) , a postdoc in our lab, for receiving the 2025 FutureHouse Fellowship! We are so proud of her and excited for what's ahead! Congrats, Laura!!
Laura Luebbert @NeuroLuebbert will work with FutureHouse and the Sabeti Lab @PardisSabeti to develop AI-driven workflows to identify viral sequences in genomic and transcriptomic datasets by leveraging conserved protein motifs. Laura is known for creating gget, a widely-adopted…
We're thrilled to announce the 2025 FutureHouse AI for Science Independent Postdoctoral Fellows—six extraordinary scientists using FutureHouse tools to solve challenging scientific problems. Fellows will have access to all released and non-released agents and tools we’ve built at…
Today, we are launching the first publicly available AI Scientist, via the FutureHouse Platform. Our AI Scientist agents can perform a wide variety of scientific tasks better than humans. By chaining them together, we've already started to discover new biology really fast. With…
Sentinel, a @sabeti_lab & @acegid_igh partnership, has been selected as a @macfound #100andChange Finalist! Sentinel is one of five teams in the running for a $100 million grant to help solve one of the world's most critical social challenges! Learn more: broad.io/Sentinel-Final…
Meet #100andChange Finalist Sentinel, one of five teams proposing a bold solution for our $100 million competition. Housed at the Sabeti Lab at the @BroadInstitute, in partnership with @acegid_igh, Sentinel seeks to transform infectious disease surveillance and response. More:…
We’re thrilled to share that our Sentinel team (a collaboration between the @sabeti_lab & @acegid_igh) has been selected as a Finalist for #100andChange! 🎉Learn more here: 100andchange.org #100andChange #LeverforChange #SocialImpact #Philanthropy
Delighted to share my tribute to Christian Happi in this year’s #TIME100. A brilliant scientist, a relentless leader, and a dear friend—his work has transformed outbreak response across Africa, built a genomic powerhouse in Nigeria, and is inspiring a generation. @TIME…
Earlier this year, Sabeti Lab members visited 🇳🇬 to collaborate with our incredible partners at @acegid_igh on LAMP diagnostics & Lassa virus sequencing. Grateful for this impactful partnership 🌍🤝 Check out our IG for more moments from the trip!
I’m thrilled to share our latest preprint! We analyzed >130,000 SARS-CoV-2 genomes from MA to investigate complex transmission dynamics—from statewide patterns, within specific facilities, and at the individual level 🦠🧬 Check out the preprint here ⬇️ medrxiv.org/content/10.110…
🎉 Huge congrats to @AriztiSanz , named a 2025 @SchmidtFellows! This global program supports early career scientists pivoting into new fields to spark innovation + drive breakthroughs. We’re so proud to see Jon leading the way! 🌍💥 read more -> bit.ly/4ciXAGk