Page Lab
@PageLabXY
Striving to understand, at the molecular level, the differences and similarities between males and females throughout the body, in health and disease.
By measuring the effects of sex chromosomes on two types of immune cells, researchers in @PageLabXY explore the biological underpinnings of sex biases in immunity and autoimmune disease: wi.mit.edu/news/immune-ce…
Consider coming to @SexDiffImmuno in June 2024 @tcddublin, co-organised with @PageLabXY to hear more about work like this…
Neurological risks of COVID-19 in women: the complex immunology underpinning sex differences frontiersin.org/articles/10.33…
"Puberty is something we all go through and is fundamental for species propagation, yet we don’t talk about it much and we still don’t know everything about it," says Alisa White, a postdoc studying sex differences in the brain. wi.mit.edu/news/meet-whit… #WhiteheadPostdocProfiles
Differences in how male and female cardiomyocytes generate energy may contribute to observed differences in heart disease. New findings from the Page lab: wi.mit.edu/news/taking-pu…
We made the cover of Genome Research! Check out our latest paper on DDX3X and DDX3Y - the first X-Y gene pair with cross regulatory capabilities (genome.cshlp.org/content/35/1/2…).
With controversy regarding the pseudoautosomal boundary, @AJHGNews latest article's analyses of the available data consistently validate the original position, narrowing the location of the boundary to a 201-bp window: cell.com/ajhg/fulltext/… @PageLabXY #ASHG #HumanGenetics
The pseudoautosomal region (PAR) is a critical area on the Y chromosome that swaps genetic information with the X chromosome. @PageLabXY reaffirms the location of PAR and offers a refined understanding of where crossover events occur. wi.mit.edu/news/establish…
🚨 Online now!! 🚨 @PageLabXY asks: Where is the boundary of the human pseudoautosomal region? cell.com/ajhg/fulltext/…
Stable and robust Xi and Y transcriptomes drive cell-type-specific autosomal and Xa responses in vivo and in vitro in four human cell types dlvr.it/TBZBTt
A day in the life of Page Lab grad student Neha Bokil wi.mit.edu/news/day-life-…
From genomic "junk" to the "inactive" X chromosome, Whitehead Institute researchers are uncovering the functions of long overlooked cellular components. #WhiteheadStoryArc wi.mit.edu/series/unsung-…
#DNADay is almost here, but we couldn't wait to share exciting DNA-centered research at the Institute. @PageLabXY uncovers the Y and "inactive" X chromosomes' far-reaching roles in gene regulation. Full video: youtu.be/MRFm8xBRY6M?si… @MITBiology @ScienceMIT
Congratulations to grad student Finn Thompson on his NSF Graduate Fellowship!
There's still time to vote for @PageLabXY in the first round of #STATmadness, @statnews's competition to find the country's most innovative research institution: statnews.com/feature/stat-m…
"Many women experience a variety of changes with menopause, and yet we know very little about the underlying biology," says Jordana Bloom, a postdoc in @PageLabXY. From the #WhiteheadPostdocProfiles archive: wi.mit.edu/news/meet-whit… @MITBiology @HHMINEWS
Looking forward to the Women's Health Track theme of sex differences at PMWC 2024 Award Ceremony with special speakers David Page from @WhiteheadInst & @PageLabXY and Janine Austin Clayton @NIH Join us on 2024-01-25, Track 3 at 9.00 A.M. #PMWC24 More at: pmwcintl.com/program
The human Y and inactive X chromosomes similarly modulate autosomal gene expression dlvr.it/T05HX6