Paul Thompson
@PTenigma
Neuroscientist, professor AI guided tour - https://www.youtube.com/watch?v=fOORfzGjCTA ENIGMA guided tour - https://www.youtube.com/watch?v=YNjP5nZsJyQ
OK, here's today's video. Guided tour of diffusion MRI + tractometry in lots of brain diseases - a bit scary in front of an audience of diffusion MRI experts who know tons more about this than I do ! youtube.com/watch?v=i2jHFm… (start at 15 min to skip the ENIGMA intro)
Out now in @natBME: We explore how rare high-effect gene-coding variants (#CNVs) shape brain architecture and influence cognitive and socio-behavioral traits in adolescents (#ABCD). nature.com/articles/s4155…
Thanks for using our brain image! I made it 28 years ago when I was a graduate student in 1997 (it’s a Hotelling’s T-squared random field attached to a cortical surface octree mesh)
yes I agree. if NIH spending is now down 33% compared with the same period in 2024 [based on analysis of data up to June 8 [1]] then, without large changes in the next 10 weeks, we could get to Sep 30 with 30% of NIH's appropriated budget unspent, and there could be an…
yes until Friday I assumed that between 7/31 and Sep 30 they could in theory give out the whole year of Congressionally appropriated money, or much more of it than so far this year, so either 1. I am wrong and this may change 2. delays will continue - and now I think they will go…
I'm not sure - like anyone else, I'm only listening to the news and talking to people I meet and at NIH, but ~40% of people I talk to think 44% cut will happen, ~20% think no cut will happen and politicians will fix it (I doubt it) +40% think something in between (~20% cut to…
I spoke with an NIH program officer yesterday who said that, given the massive 44% cut planned for NIH, they were only planning to award about 12 new grants before the end of the year, which are mainly ones in the 1st and 2nd percentile, so the 3 grants we had with good scores…
The NIH has decided that scientists can only submit 6 grants a year. OK. But you need a score that’s < 10% at least to get funded. Meaning, at best, 1 out of 10 grants you submit will have a chance (YMMV of course). 🫠
Writing 2 grants at the same time while watching this (which seems equally fun)
✨🧠Excited to have had the opportunity to present our work titled 'Diffusion Bridge Models for 3D Medical Image Translation' in IEEE #embc2025 conference. Some of the important points of discussion from the paper are in this 🧵
I agree with your analysis 100% - in fact, I predicted this on March 1st and everything I predicted has actually happened since then ( x.com/PTenigma/statu… ). They even have published some formulas for the effect on new grants ( x.com/PTenigma/statu… ) but none of these has…
"A 7.14% decrease in the budget leads to a 28.57% fall in the success rate." Here's the paper I was trying to find yesterday when NIH's websites were down [1,2]. If NIH's budget is cut 20% on March 14, the success rate would decrease by 80%.* [1] Simple explainer -…
ASL CBF changes with AD stages, indicating the value of ASL for detecting and monitoring AD progression
🌟 New week, new animation 🧠 Research by our @loft_lab uses noninvasive ASL MRI to show that brain blood flow decreases even in the earliest stages of Alzheimer’s — before memory problems appear. This could help doctors catch the disease earlier and track treatment over time.
I'm curious if @stevenstrogatz or anyone in MRI physics has already used Kuramoto's model to describe the time-evolution of phase distributions in MRI (as the same math underlies MRI fid (free induction decay)+ the coherence loss in a 0-coupling Kuramoto ensemble)? The rotating…