James Olzmann
@OlzmannLab
Professor of Molecular Therapeutics and Metabolic Biology at UC Berkeley; Departments of Molecular & Cell Biology and Nutritional Sciences & Toxicology
Excited to share our new preprint! Exceptional work by postdoc @MikeLange identifies the first #LipidDroplet lipid quality control pathway! Droplet-localized FSP1 safeguards stored neutral lipids, blocking their peroxidation & #ferroptosis induction.🤩biorxiv.org/content/10.110…
check out our new paper measuring intracellular forces: Nodal modulator (NOMO) is a force-bearing transmembrane protein contributing to a dynamic network of organelle-shaping proteins rupress.org/jcb/article/22…
we suggest that multiple, weak ER spacer interactions create a system that is sufficiently dynamic to allow for secretion and passage of bulky cargo, yet avidity effects support organelle integrity and force buffering
check out our new paper measuring intracellular forces: Nodal modulator (NOMO) is a force-bearing transmembrane protein contributing to a dynamic network of organelle-shaping proteins rupress.org/jcb/article/22…
Arrived in Scottsdale Arizona for the @FASEBorg #Ferroptosis conference!! Who is excited?! Me!!! See you soon my friends! 🌵 #Ferroptosis25



Thankful for these wonderful colleagues @BerkeleyMetBio. ☺️ @gparlakgul @Ale_Ferrari1 @apsarruda @Denis_V_Titov et al.

Thank you @ZouYilong and Charles David for this thoughtful commentary on our recent study connecting PCSK9 status with PDAC metastatic tropism
New online! A marker for sterol-dependent metastatic tropism bit.ly/4kIhqOc
General Sherman in Sequoia National Park in California, the world’s largest tree! Wow! Those specks at the base are people! 🤩 Height = 274.9 feet (83.8 meters) Diameter at the base = 36.5 feet (11.1 meters) Estimated Age: 2,200 years


Tenure-track faculty search of the @Ucsf_Biochem Department is open for applications! We are looking for creative, innovative scientists asking fundamental questions in any area of biology. Join our vibrant, collaborative, and supportive community! aprecruit.ucsf.edu/JPF05702
It’s great to see our @RapeLab paper being highlighted @CellChemBiol . Thank you @LanderLab for your comments!!
Silencing stress: Structural insights into ISR termination by the SIFI ubiquitin ligase dlvr.it/TM03Rt
Grateful to everyone who brought #BayAreaBiotechDay to life yesterday at @UCBerkeley! It was incredible to see the energy in the room and the cutting-edge advances shared by leaders in both academia and industry. Excited to see what’s next for biotech!
After a couple years of tons of work.. very excited to see that the pre-order for the 5th edition of Biochemical, Physiological and Molecular Aspects of Human Nutrition is live! This 5th Edition has a ton of updates in terms of both content and figures and I think continues to…
Backed by a $100M gift from Joan and Sandy Weill, UCSF and @StanfordMed @StanfordCancer are launching Weill Cancer Hub West, a $200M initiative in team science to accelerate cancer research and improve care over the next decade. tiny.ucsf.edu/ppVRqt
Launched today- the Weill Cancer Hub West -supporting transformative cancer research collaborations btw @UCSF & @Stanford. Honored to co-lead, with @longlabstanford, our team who will study the impact of diet on pancreatic cancer initiation, progression and therapy response.
Backed by a $100M gift from Joan and Sandy Weill, UCSF and @StanfordMed @StanfordCancer are launching Weill Cancer Hub West, a $200M initiative in team science to accelerate cancer research and improve care over the next decade. tiny.ucsf.edu/ppVRqt
More on the Weill Cancer Hub West in the SF Chronicle 👇
This cancer center, the largest of its kind on the West Coast, aims to dramatically improve prevention and treatment over the next decade, with a focus on data-driven AI methods. sfchronicle.com/health/article…
We have an Open Rank tenure-track faculty position in the Department of Nutrition & Integrative Physiology! Looking for a new colleague interested in making the Univ. of Utah their new home to build a metabolic research program. Please share! @uofunuip jobs.sciencecareers.org/job/674355
1/ Better late than never, here’s a long thread of threads summarizing our MOSAIC preprint. If you’re curious about the process by which a new microscope is conceived and brought into the world, this is the thread for you. If you’ve come for eye candy, there’s plenty of that too…
Silencing stress: Structural insights into ISR termination by the SIFI ubiquitin ligase dlvr.it/TM03Rt
The count down has begun! 1-week until the 1st FASEB Ferroptosis conference! Looking forward to seeing everyone at the meeting. Get excited!! 🤩 events.faseb.org/event/11797f9e…

Exciting event coming to @berkeleyMCB ,#MolecularTherapeutics, @MTI_UCB !
🚨 Bay Area Biotech Day hits @UCBerkeley next week (7/22)! Hear Nobel laureate Carolyn Bertozzi + leaders from Denali, Calico, Frontier, Nurix, Arcus & more on the next wave of drug discovery. 🧬 Posters, panels & networking. #Biotech #DrugDiscovery #UCBerkeley
What could be more fun that connecting @UCBerkeley students and trailblazing biotechs, and hearing @CarolynBertozzi deliver an inspiring Keynote?
🚨 Bay Area Biotech Day hits @UCBerkeley next week (7/22)! Hear Nobel laureate Carolyn Bertozzi + leaders from Denali, Calico, Frontier, Nurix, Arcus & more on the next wave of drug discovery. 🧬 Posters, panels & networking. #Biotech #DrugDiscovery #UCBerkeley
Congratulations @SvenssonLab @Gemma_MZ on the discovery of a mammalian fructose sensor👏🏻 cell.com/cell-reports/f…